Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BLNK
  • Mouse genes Blnk
  • Rat genes Blnk
  • Zfish genes blnk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Blnk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	BLNK	IPI	UniProtKB:P19174	Human	PMID:9697839
Molecular Function	GO:0008289	lipid binding	BLNK	EXP		Human	PMID:25140054
Molecular Function	GO:0043274	phospholipase binding	BLNK	IPI	UniProtKB:P16885	Human	PMID:11606584
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:P62993	Human	PMID:16912232
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:Q06187	Human	PMID:16969585
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:P62993	Human	PMID:21822214
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:Q5ZMQ7	Human	PMID:21822214
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:Q9Y5K6	Human	PMID:21822214
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:Q6UWF3	Human	PMID:21930792
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:P10275	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:P15498	Human	PMID:9697839
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:P16333	Human	PMID:9697839
Molecular Function	GO:0005515	protein binding	BLNK	IPI	UniProtKB:P62993	Human	PMID:9697839
Molecular Function	GO:0005515	protein binding	Blnk	IPI	UniProtKB:Q3UU41	Mouse	MGI:MGI:6317162|PMID:28290451
Molecular Function	GO:0005515	protein binding	Blnk	IPI	UniProtKB:Q3UU41	Mouse	MGI:MGI:5300118|PMID:21930792
Molecular Function	GO:0005515	protein binding	Blnk	IPI	PR:Q99LJ5	Mouse	PMID:15196959
Molecular Function	GO:0005515	protein binding	Blnk	IPI	PR:P23611	Mouse	PMID:25331958
Molecular Function	GO:0019901	protein kinase binding	BLNK	IPI	UniProtKB:P43405	Human	PMID:11606584
Molecular Function	GO:1990782	protein tyrosine kinase binding	BLNK	IPI	UniProtKB:F1N9Y5	Human	PMID:9697839
Molecular Function	GO:0042169	SH2 domain binding	BLNK	IDA		Human	PMID:9697839
Molecular Function	GO:0035591	signaling adaptor activity	BLNK	IDA		Human	PMID:11606584
Molecular Function	GO:0035591	signaling adaptor activity	BLNK	IDA		Human	PMID:9697839
Cellular Component	GO:0005737	cytoplasm	Blnk	IDA		Mouse	PMID:15196959
Cellular Component	GO:0005829	cytosol	BLNK	IDA		Human	PMID:9697839
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	BLNK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	BLNK	IDA		Human	PMID:9697839
Cellular Component	GO:0005886	plasma membrane	BLNK	IDA		Human	GO_REF:0000052
Biological Process	GO:0050853	B cell receptor signaling pathway	BLNK	IMP		Human	PMID:11606584
Biological Process	GO:0050853	B cell receptor signaling pathway	BLNK	IDA		Human	PMID:9697839
Biological Process	GO:0035556	intracellular signal transduction	BLNK	IDA		Human	PMID:11606584
Biological Process	GO:0035556	intracellular signal transduction	BLNK	IDA		Human	PMID:9341187
Biological Process	GO:0010628	positive regulation of gene expression	Blnk	IMP		Mouse	MGI:MGI:5444793|PMID:22949502

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern