Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BLOC1S2
  • Mouse genes Bloc1s2
  • Rat genes Bloc1s2
  • Zfish genes bloc1s2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bloc1s2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043015	gamma-tubulin binding	BLOC1S2	IDA		Human	PMID:15381421
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:O95295	Human	PMID:15102850
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:P78537	Human	PMID:15102850
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q6QNY0	Human	PMID:15102850
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q9NWB7	Human	PMID:18188704
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q9NPI1	Human	PMID:18329849
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:O95295	Human	PMID:22203680
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:P78537	Human	PMID:22203680
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:O95295	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:O95295,UniProtKB:P78537,UniProtKB:Q969J3,UniProtKB:Q96B45,UniProtKB:Q96FH0,UniProtKB:Q96GS4,UniProtKB:Q9BQD3	Human	PMID:25898167
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q8N7C3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q9Y3C0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:A1L4H1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:O95257	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:O95295	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:P24863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:P32856-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:P53365	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:P55040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q13515	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q13561	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q7Z3Y9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q7Z4N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q8IYE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q8IYI6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q8N7C3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q8TD31-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q96DN0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q96MY7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q9H788	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q9UI47-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BLOC1S2	IPI	UniProtKB:Q9Y3C0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Bloc1s2	IPI	PR:Q9Z266	Mouse	PMID:15102850
Molecular Function	GO:0005515	protein binding	Bloc1s2	IPI	PR:Q5U5M8	Mouse	PMID:15102850
Molecular Function	GO:0005515	protein binding	Bloc1s2	IPI	PR:O55102	Mouse	PMID:15102850
Cellular Component	GO:0031083	BLOC-1 complex	BLOC1S2	IPI		Human	PMID:22203680
Cellular Component	GO:0031083	BLOC-1 complex	BLOC1S2	IDA		Human	PMID:15102850
Cellular Component	GO:0031083	BLOC-1 complex	BLOC1S2	IDA		Human	PMID:22203680
Cellular Component	GO:0031083	BLOC-1 complex	Bloc1s2	IDA		Mouse	PMID:15102850
Cellular Component	GO:0099078	BORC complex	BLOC1S2	IPI		Human	PMID:25898167
Cellular Component	GO:0099078	BORC complex	BLOC1S2	IDA		Human	PMID:25898167
Cellular Component	GO:0005813	centrosome	Bloc1s2	IDA		Rat	PMID:17552904|RGD:2302153
Cellular Component	GO:0005737	cytoplasm	Bloc1s2	IDA		Rat	PMID:16176350|RGD:2302154
Cellular Component	GO:0005829	cytosol	Bloc1s2	IDA		Mouse	PMID:15102850
Cellular Component	GO:0000930	gamma-tubulin complex	BLOC1S2	IDA		Human	PMID:15381421
Cellular Component	GO:0005739	mitochondrion	BLOC1S2	IDA		Human	PMID:18188704
Cellular Component	GO:0005634	nucleus	Bloc1s2	IDA		Rat	PMID:17552904|RGD:2302153
Cellular Component	GO:0055037	recycling endosome	Bloc1s2	IDA		Rat	PMID:17552904|RGD:2302153
Biological Process	GO:0008089	anterograde axonal transport	Bloc1s2	IMP		Mouse	MGI:MGI:5437407|PMID:21998198
Biological Process	GO:0048490	anterograde synaptic vesicle transport	Bloc1s2	IMP		Mouse	MGI:MGI:5437407|PMID:21998198
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	BLOC1S2	IDA		Human	PMID:18188704
Biological Process	GO:0032418	lysosome localization	BLOC1S2	IMP		Human	PMID:25898167
Biological Process	GO:0097345	mitochondrial outer membrane permeabilization	BLOC1S2	IDA		Human	PMID:18188704
Biological Process	GO:1905457	negative regulation of lymphoid progenitor cell differentiation	bloc1s2	IMP	ZFIN:ZDB-GENO-170202-18	Zfish	PMID:27719760
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	bloc1s2	IMP	ZFIN:ZDB-GENO-170202-18	Zfish	PMID:27719760
Biological Process	GO:1902038	positive regulation of hematopoietic stem cell differentiation	bloc1s2	IMP	ZFIN:ZDB-GENO-170202-18	Zfish	PMID:27719760
Biological Process	GO:1905455	positive regulation of myeloid progenitor cell differentiation	bloc1s2	IMP	ZFIN:ZDB-GENO-170202-18	Zfish	PMID:27719760
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bloc1s2	IMP		Rat	PMID:17552904|RGD:2302153

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern