Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BMP1
  • Mouse genes Bmp1
  • Rat genes Bmp1
  • Zfish genes bmp1a,bmp1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bmp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	BMP1	IPI	UniProtKB:P13497	Human	PMID:19429706
Molecular Function	GO:0004222	metalloendopeptidase activity	Bmp1	IDA		Mouse	PMID:19079247
Molecular Function	GO:0008233	peptidase activity	BMP1	IDA		Human	PMID:12393877
Molecular Function	GO:0008233	peptidase activity	BMP1	IDA		Human	PMID:16824737
Molecular Function	GO:0008233	peptidase activity	bmp1a	IDA		Zfish	PMID:16518392
Molecular Function	GO:0008233	peptidase activity	bmp1a	IDA		Zfish	PMID:16824737
Molecular Function	GO:0005515	protein binding	BMP1	IPI	UniProtKB:Q9H2X0	Human	PMID:19429706
Molecular Function	GO:0005515	protein binding	BMP1	IPI	UniProtKB:Q9H2X0	Human	PMID:20043912
Molecular Function	GO:0005515	protein binding	BMP1	IPI	UniProtKB:Q15113	Human	PMID:20207734
Molecular Function	GO:0005515	protein binding	BMP1	IPI	UniProtKB:P20908	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	BMP1	IPI	UniProtKB:Q15113	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	BMP1	IPI	UniProtKB:O14793	Human	PMID:23829672
Molecular Function	GO:0005515	protein binding	BMP1	IPI	UniProtKB:O14793	Human	PMID:25543063
Molecular Function	GO:0005515	protein binding	Bmp1	IPI	PR:P97299	Mouse	PMID:19079247
Molecular Function	GO:0005515	protein binding	bmp1a	IPI	ZFIN:ZDB-GENE-030530-1	Zfish	PMID:16518392
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Bmp1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005615	extracellular space	Bmp1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Bmp1	IDA		Rat	PMID:18758911|RGD:2301841
Cellular Component	GO:0031982	vesicle	Bmp1	IDA		Rat	PMID:18758911|RGD:2301841
Biological Process	GO:0032964	collagen biosynthetic process	bmp1a	IMP	ZFIN:ZDB-GENO-180622-2	Zfish	PMID:30082390
Biological Process	GO:0048264	determination of ventral identity	bmp1a	IMP	ZFIN:ZDB-MRPHLNO-060818-1	Zfish	PMID:16518392
Biological Process	GO:0048264	determination of ventral identity	bmp1a	IMP	ZFIN:ZDB-MRPHLNO-060818-3	Zfish	PMID:16518392
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp1a	IGI	ZFIN:ZDB-MRPHLNO-041217-9,ZFIN:ZDB-MRPHLNO-050221-6,ZFIN:ZDB-MRPHLNO-060818-1	Zfish	PMID:20886103
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp1a	IGI	ZFIN:ZDB-MRPHLNO-060818-1,ZFIN:ZDB-MRPHLNO-060818-2	Zfish	PMID:16518392
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp1a	IGI	ZFIN:ZDB-MRPHLNO-041217-9,ZFIN:ZDB-MRPHLNO-060818-1,ZFIN:ZDB-MRPHLNO-060818-2	Zfish	PMID:20886103
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp1a	IGI	ZFIN:ZDB-MRPHLNO-041217-9,ZFIN:ZDB-MRPHLNO-060818-1	Zfish	PMID:16518392
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp1a	IMP	ZFIN:ZDB-MRPHLNO-060818-4	Zfish	PMID:16824737
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp1a	IGI	ZFIN:ZDB-MRPHLNO-060818-4,ZFIN:ZDB-MRPHLNO-060818-7	Zfish	PMID:16824737
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp1a	IGI	ZFIN:ZDB-MRPHLNO-041217-9,ZFIN:ZDB-MRPHLNO-060818-1,ZFIN:ZDB-MRPHLNO-060818-2	Zfish	PMID:16518392
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp1a	IMP	ZFIN:ZDB-MRPHLNO-060818-6	Zfish	PMID:16824737
Biological Process	GO:0033333	fin development	bmp1a	IMP		Zfish	PMID:9007245
Biological Process	GO:0001503	ossification	bmp1a	IMP	ZFIN:ZDB-GENO-111013-6	Zfish	PMID:22482805
Biological Process	GO:0061036	positive regulation of cartilage development	BMP1	IDA		Human	PMID:3201241
Biological Process	GO:0006508	proteolysis	BMP1	IDA		Human	PMID:16824737
Biological Process	GO:0006508	proteolysis	bmp1a	IDA		Zfish	PMID:16518392
Biological Process	GO:0006508	proteolysis	bmp1a	IDA		Zfish	PMID:16824737
Biological Process	GO:0001501	skeletal system development	bmp1a	IMP	ZFIN:ZDB-GENO-180622-2	Zfish	PMID:28884682

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern