Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BMP10
  • Mouse genes Bmp10
  • Rat genes Bmp10
  • Zfish genes bmp10,bmp10l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bmp10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005179	hormone activity	BMP10	IDA		Human	PMID:17921333
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P37023	Human	PMID:17068149
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:O15273	Human	PMID:17921333
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P35555	Human	PMID:18339631
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P35556	Human	PMID:18339631
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:J3KQ12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:O43557	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:O75208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:O95424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P02730	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P08034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P12314	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P20138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P26715	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P26951	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P30040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P32971	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P43628	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P43629	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:P57738	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q12999	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q5VZY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q6NSX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q6P531	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q6Q788	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q8N386	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q8N5K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q8WZ55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q96B21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q96HJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q96PJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9H2H9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9H7M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9HCJ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9NPE6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9Y3P8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9Y676	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP10	IPI	UniProtKB:Q9Y680	Human	PMID:32296183
Molecular Function	GO:0033612	receptor serine/threonine kinase binding	BMP10	IDA		Human	PMID:17068149
Molecular Function	GO:0031433	telethonin binding	BMP10	IPI	UniProtKB:O15273	Human	PMID:17921333
Cellular Component	GO:0009986	cell surface	BMP10	IDA		Human	PMID:17921333
Cellular Component	GO:0005737	cytoplasm	BMP10	IDA		Human	PMID:17921333
Cellular Component	GO:0005615	extracellular space	BMP10	IDA		Human	PMID:17921333
Cellular Component	GO:0030018	Z disc	BMP10	IDA		Human	PMID:17921333
Biological Process	GO:0032924	activin receptor signaling pathway	BMP10	IDA		Human	PMID:16049014
Biological Process	GO:0032924	activin receptor signaling pathway	BMP10	IDA		Human	PMID:17068149
Biological Process	GO:0007512	adult heart development	Bmp10	IMP		Mouse	MGI:MGI:3695247|PMID:16798733
Biological Process	GO:0060840	artery development	bmp10	IGI	ZFIN:ZDB-MRPHLNO-131001-3,ZFIN:ZDB-MRPHLNO-131003-7	Zfish	PMID:23863480
Biological Process	GO:0060840	artery development	bmp10l	IGI	ZFIN:ZDB-MRPHLNO-131001-3,ZFIN:ZDB-MRPHLNO-131003-7	Zfish	PMID:23863480
Biological Process	GO:0055009	atrial cardiac muscle tissue morphogenesis	Bmp10	IEP		Mouse	MGI:MGI:1332872|PMID:10072785
Biological Process	GO:0030509	BMP signaling pathway	BMP10	IDA		Human	PMID:16049014
Biological Process	GO:0030509	BMP signaling pathway	BMP10	IDA		Human	PMID:17068149
Biological Process	GO:0060038	cardiac muscle cell proliferation	Bmp10	IMP		Mouse	MGI:MGI:3040529|PMID:15073151
Biological Process	GO:0007507	heart development	Bmp10	IMP	MGI:MGI:3042354	Mouse	PMID:15073151
Biological Process	GO:0060347	heart trabecula formation	Bmp10	IMP		Mouse	MGI:MGI:3040529|PMID:15073151
Biological Process	GO:0001822	kidney development	Bmp10	IMP	MGI:MGI:5616117	Mouse	PMID:27002738
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	Bmp10	IMP		Mouse	MGI:MGI:3695247|PMID:16798733
Biological Process	GO:0030308	negative regulation of cell growth	BMP10	IDA		Human	PMID:17068149
Biological Process	GO:0030336	negative regulation of cell migration	BMP10	IDA		Human	PMID:17068149
Biological Process	GO:0010596	negative regulation of endothelial cell migration	BMP10	IDA		Human	PMID:17068149
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	BMP10	IDA		Human	PMID:16049014
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	BMP10	IDA		Human	PMID:17068149
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	Bmp10	IDA		Mouse	MGI:MGI:3695247|PMID:16798733
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	Bmp10	IMP		Mouse	MGI:MGI:3701380|PMID:17336907
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	BMP10	IMP		Human	PMID:17921333
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	Bmp10	IMP		Rat	PMID:17921333|RGD:2302083
Biological Process	GO:0061036	positive regulation of cartilage development	Bmp10	IDA		Mouse	MGI:MGI:5621263|PMID:19956691
Biological Process	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	Bmp10	IGI	UniProtKB:P31266	Mouse	MGI:MGI:3701380|PMID:17336907
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BMP10	IDA		Human	PMID:16049014
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BMP10	IDA		Human	PMID:17068149
Biological Process	GO:0010628	positive regulation of gene expression	Bmp10	IDA		Mouse	PMID:22783020
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP10	IDA		Human	PMID:16049014
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP10	IDA		Human	PMID:17068149
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP10	IDA		Human	PMID:19903896
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	Bmp10	IDA		Mouse	MGI:MGI:3695247|PMID:16798733
Biological Process	GO:0060298	positive regulation of sarcomere organization	BMP10	IDA		Human	PMID:17921333
Biological Process	GO:0055117	regulation of cardiac muscle contraction	BMP10	IMP		Human	PMID:17921333
Biological Process	GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	BMP10	IDA		Human	PMID:17921333
Biological Process	GO:0045214	sarcomere organization	Bmp10	IMP		Rat	PMID:17921333|RGD:2302083
Biological Process	GO:0055015	ventricular cardiac muscle cell development	Bmp10	IDA		Mouse	MGI:MGI:3695247|PMID:16798733
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	Bmp10	IMP		Mouse	MGI:MGI:3701380|PMID:17336907
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	Bmp10	IMP		Mouse	MGI:MGI:3040529|PMID:15073151

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern