Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BMP2
  • Mouse genes Bmp2
  • Rat genes Bmp2
  • Zfish genes bmp2a,bmp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bmp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070700	BMP receptor binding	BMP2	IDA		Human	PMID:7811286
Molecular Function	GO:0039706	co-receptor binding	BMP2	IPI	UniProtKB:Q7TQ32	Human	PMID:16604073
Molecular Function	GO:0039706	co-receptor binding	BMP2	IPI	UniProtKB:Q6ZVN8	Human	PMID:18335997
Molecular Function	GO:0005125	cytokine activity	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Molecular Function	GO:0008083	growth factor activity	Bmp2	IDA		Rat	PMID:12398941|RGD:631753
Molecular Function	GO:0042802	identical protein binding	Bmp2	IPI	RGD:2211	Rat	PMID:12871556|RGD:1600787
Molecular Function	GO:0042802	identical protein binding	bmp2b	IPI	ZFIN:ZDB-GENE-980526-474	Zfish	PMID:19377468
Molecular Function	GO:0019211	phosphatase activator activity	BMP2	IDA		Human	PMID:9213002
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P36894	Human	PMID:10881198
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P36894	Human	PMID:15064755
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P27038	Human	PMID:16672363
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P36894	Human	PMID:16672363
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P98066	Human	PMID:16771708
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q18530	Human	PMID:17240342
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:O00238	Human	PMID:18184661
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P36894	Human	PMID:18184661
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q03167	Human	PMID:18184661
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q6ZVN8	Human	PMID:18335997
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P35555	Human	PMID:18339631
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P35556	Human	PMID:18339631
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:O00238	Human	PMID:19229295
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P36894	Human	PMID:19804412
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q13253	Human	PMID:19804412
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P25304	Human	PMID:20505824
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P36894	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q12841	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P36894	Human	PMID:21054789
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P36894	Human	PMID:25938661
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q6NW40	Human	PMID:25938661
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q6ZVN8-1	Human	PMID:25938661
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q96B86-1	Human	PMID:25938661
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q8IX30	Human	PMID:33308444
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:G8JY02	Human	PMID:8413626
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:P50488	Human	PMID:8413626
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q8ITX8	Human	PMID:8413626
Molecular Function	GO:0005515	protein binding	BMP2	IPI	UniProtKB:Q13253	Human	PMID:8752214
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	UniProtKB:Q9QZJ6	Mouse	MGI:MGI:5529228|PMID:23963447
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	UniProtKB:Q99MQ4	Mouse	MGI:MGI:3722035|PMID:17522060
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	UniProtKB:O95388	Mouse	MGI:MGI:5304253|PMID:20684029
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	PR:P11087	Mouse	PMID:17018525
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	PR:Q9R0G6	Mouse	PMID:21350216
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	PR:Q8CJ69	Mouse	PMID:12897139
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	PR:Q8VEA6	Mouse	PMID:14660436
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	PR:Q6PCX7	Mouse	PMID:15975920
Molecular Function	GO:0005515	protein binding	Bmp2	IPI	PR:Q9CQN4	Mouse	PMID:14623234
Molecular Function	GO:0019904	protein domain specific binding	Bmp2	IPI	RGD:3088	Rat	PMID:12871556|RGD:1600787
Molecular Function	GO:0046982	protein heterodimerization activity	bmp2b	IPI	UniProtKB:Q9PTF9	Zfish	PMID:19377468
Molecular Function	GO:0048018	receptor ligand activity	Bmp2	IDA		Mouse	PMID:7798324
Molecular Function	GO:0048018	receptor ligand activity	Bmp2	IDA		Mouse	PMID:21976273
Molecular Function	GO:0046332	SMAD binding	BMP2	IDA		Human	PMID:18184661
Cellular Component	GO:0070724	BMP receptor complex	BMP2	IDA		Human	PMID:16604073
Cellular Component	GO:0009986	cell surface	BMP2	IDA		Human	PMID:22227436
Cellular Component	GO:0005737	cytoplasm	Bmp2	IDA		Rat	PMID:15589212|RGD:2289014
Cellular Component	GO:0005576	extracellular region	Bmp2	IDA		Mouse	PMID:21976273
Cellular Component	GO:0005615	extracellular space	BMP2	IDA		Human	PMID:16604073
Cellular Component	GO:0005615	extracellular space	Bmp2	IDA		Mouse	PMID:15110716
Cellular Component	GO:0005615	extracellular space	Bmp2	IDA		Rat	PMID:18758911|RGD:2301841
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	BMP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Bmp2	IDA		Mouse	PMID:7798324
Cellular Component	GO:0032991	protein-containing complex	Bmp2	IDA		Rat	PMID:12871556|RGD:1600787
Cellular Component	GO:0031982	vesicle	Bmp2	IDA		Rat	PMID:18758911|RGD:2301841
Biological Process	GO:0036305	ameloblast differentiation	Bmp2	IDA		Mouse	PMID:15525533
Biological Process	GO:0009887	animal organ morphogenesis	Bmp2	IMP	MGI:MGI:1857894	Mouse	PMID:8898212
Biological Process	GO:0003176	aortic valve development	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0048708	astrocyte differentiation	Bmp2	IDA		Mouse	PMID:15882580
Biological Process	GO:0048708	astrocyte differentiation	Bmp2	IGI	MGI:MGI:99414	Mouse	PMID:15882580
Biological Process	GO:1905222	atrioventricular canal morphogenesis	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0003181	atrioventricular valve morphogenesis	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IMP		Human	PMID:17472960
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IDA		Human	PMID:16049014
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IEP		Human	PMID:16194878
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IDA		Human	PMID:16771708
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IMP		Human	PMID:18326817
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IDA		Human	PMID:18382765
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IDA		Human	PMID:18436533
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IMP		Human	PMID:19664780
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IDA		Human	PMID:20427544
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IDA		Human	PMID:20843790
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IGI	RNAcentral:URS0000574A2C_9606	Human	PMID:22450430
Biological Process	GO:0030509	BMP signaling pathway	BMP2	IMP		Human	PMID:24778011
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Mouse	MGI:MGI:3795340|PMID:18382765
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Mouse	PMID:7798324
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Mouse	PMID:21976273
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Mouse	PMID:20065295
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Mouse	PMID:19208758
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IGI	MGI:MGI:2679262	Mouse	PMID:15975920
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Mouse	PMID:19852960
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Mouse	PMID:25100727
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Mouse	PMID:14623234
Biological Process	GO:0030509	BMP signaling pathway	Bmp2	IDA		Rat	PMID:12398941|RGD:631753
Biological Process	GO:0030509	BMP signaling pathway	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-050902-2	Zfish	PMID:19377468
Biological Process	GO:0061312	BMP signaling pathway involved in heart development	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0003130	BMP signaling pathway involved in heart induction	BMP2	IDA		Human	PMID:19736317
Biological Process	GO:0060348	bone development	Bmp2	IMP	MGI:MGI:3696052	Mouse	PMID:20551513
Biological Process	GO:0030282	bone mineralization	Bmp2	IGI	MGI:MGI:1922667	Mouse	PMID:19213727
Biological Process	GO:0030282	bone mineralization	Bmp2	IDA		Mouse	PMID:19213727
Biological Process	GO:0030282	bone mineralization	Bmp2	IGI	MGI:MGI:101948	Mouse	PMID:19213727
Biological Process	GO:0030282	bone mineralization	Bmp2	IDA		Mouse	PMID:15657444
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Bmp2	IGI	MGI:MGI:104903	Mouse	PMID:15925496
Biological Process	GO:0003210	cardiac atrium formation	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0060317	cardiac epithelial to mesenchymal transition	BMP2	IDA		Human	PMID:18184661
Biological Process	GO:1905072	cardiac jelly development	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0055007	cardiac muscle cell differentiation	BMP2	IMP		Human	PMID:21311046
Biological Process	GO:0055007	cardiac muscle cell differentiation	Bmp2	IGI	UniProtKB:P21275	Mouse	MGI:MGI:4939577|PMID:21145505
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0035051	cardiocyte differentiation	BMP2	IDA		Human	PMID:15110716
Biological Process	GO:0035051	cardiocyte differentiation	BMP2	IMP		Human	PMID:19736317
Biological Process	GO:0045165	cell fate commitment	Bmp2	IMP		Mouse	PMID:12421925
Biological Process	GO:0042074	cell migration involved in gastrulation	bmp2b	IGI	ZFIN:ZDB-GENO-980202-1488,ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0045168	cell-cell signaling involved in cell fate commitment	bmp2b	IMP		Zfish	PMID:9409664
Biological Process	GO:0071773	cellular response to BMP stimulus	BMP2	IMP		Human	PMID:18326817
Biological Process	GO:0071773	cellular response to BMP stimulus	BMP2	IDA		Human	PMID:20843790
Biological Process	GO:0071773	cellular response to BMP stimulus	Bmp2	IEP		Rat	PMID:9246083|RGD:8699515
Biological Process	GO:0071363	cellular response to growth factor stimulus	Bmp2	IDA		Mouse	PMID:7848824
Biological Process	GO:0071260	cellular response to mechanical stimulus	Bmp2	IEP		Rat	PMID:20877159|RGD:9068439
Biological Process	GO:0071407	cellular response to organic cyclic compound	Bmp2	IDA		Mouse	PMID:19103752
Biological Process	GO:0002062	chondrocyte differentiation	BMP2	IDA		Human	PMID:16194878
Biological Process	GO:0060128	corticotropin hormone secreting cell differentiation	Bmp2	IDA		Mouse	PMID:9463347
Biological Process	GO:0007368	determination of left/right symmetry	bmp2b	IMP	ZFIN:ZDB-GENO-070710-1	Zfish	PMID:17395172
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IMP	ZFIN:ZDB-GENO-980202-960	Zfish	PMID:11222140
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IGI	ZFIN:ZDB-MRPHLNO-050902-2,ZFIN:ZDB-MRPHLNO-050902-3	Zfish	PMID:16527746
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-050902-2	Zfish	PMID:24525188
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IMP		Zfish	PMID:9007231
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IDA		Zfish	PMID:11091070
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IDA		Zfish	PMID:21145463
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-050902-2	Zfish	PMID:16527746
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IDA		Zfish	PMID:11222140
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-050902-2	Zfish	PMID:11477698
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IDA		Zfish	PMID:9076679
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IMP	ZFIN:ZDB-GENO-980202-1071	Zfish	PMID:12601179
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-041217-6	Zfish	PMID:11222140
Biological Process	GO:0048264	determination of ventral identity	bmp2b	IGI	ZFIN:ZDB-GENE-020812-3	Zfish	PMID:15525664
Biological Process	GO:0060030	dorsal convergence	bmp2b	IGI	ZFIN:ZDB-MRPHLNO-060930-5	Zfish	PMID:17331724
Biological Process	GO:0060030	dorsal convergence	bmp2b	IGI	ZFIN:ZDB-GENE-990415-171	Zfish	PMID:17331724
Biological Process	GO:0060030	dorsal convergence	bmp2b	IDA		Zfish	PMID:17331724
Biological Process	GO:0060030	dorsal convergence	bmp2b	IGI	ZFIN:ZDB-MRPHLNO-050221-6	Zfish	PMID:17331724
Biological Process	GO:0009950	dorsal/ventral axis specification	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-050902-2	Zfish	PMID:24308972
Biological Process	GO:0009950	dorsal/ventral axis specification	bmp2b	IMP	ZFIN:ZDB-GENO-140210-10	Zfish	PMID:24204286
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-041217-6	Zfish	PMID:32064309
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IMP	ZFIN:ZDB-GENO-980202-1488	Zfish	PMID:11969259
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IMP	ZFIN:ZDB-GENO-081224-1	Zfish	PMID:11748837
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IGI	ZFIN:ZDB-GENO-100422-2	Zfish	PMID:11748837
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IDA		Zfish	PMID:16775002
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IMP	ZFIN:ZDB-GENO-980202-1488	Zfish	PMID:15269175
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IEP		Zfish	PMID:9076679
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IGI	ZFIN:ZDB-GENO-980202-1488,ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-041217-6	Zfish	PMID:24332754
Biological Process	GO:0009790	embryo development	Bmp2	IMP	MGI:MGI:1857894	Mouse	PMID:8898212
Biological Process	GO:0035054	embryonic heart tube anterior/posterior pattern specification	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	bmp2b	IGI	ZFIN:ZDB-GENE-081006-2	Zfish	PMID:27130837
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	bmp2b	IMP		Zfish	PMID:27130837
Biological Process	GO:0003272	endocardial cushion formation	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0003203	endocardial cushion morphogenesis	Bmp2	IMP		Mouse	MGI:MGI:4837019|PMID:20890042
Biological Process	GO:0003203	endocardial cushion morphogenesis	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0048484	enteric nervous system development	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-101112-1	Zfish	PMID:31849612
Biological Process	GO:0001837	epithelial to mesenchymal transition	BMP2	IDA		Human	PMID:15110716
Biological Process	GO:0001837	epithelial to mesenchymal transition	BMP2	IDA		Human	PMID:18184661
Biological Process	GO:0001837	epithelial to mesenchymal transition	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0001837	epithelial to mesenchymal transition	Bmp2	IMP		Mouse	MGI:MGI:5299248|PMID:21983003
Biological Process	GO:0031017	exocrine pancreas development	bmp2a	IGI	ZFIN:ZDB-GENE-041011-3	Zfish	PMID:31705616
Biological Process	GO:0010467	gene expression	Bmp2	IDA		Mouse	PMID:12397106
Biological Process	GO:0007507	heart development	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0090008	hypoblast development	bmp2b	IMP		Zfish	PMID:9076679
Biological Process	GO:0001701	in utero embryonic development	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0006954	inflammatory response	Bmp2	IEP		Mouse	MGI:MGI:3693397|PMID:12151307
Biological Process	GO:0048839	inner ear development	Bmp2	IDA		Mouse	PMID:21795542
Biological Process	GO:0001889	liver development	bmp2b	IMP	ZFIN:ZDB-GENO-070712-2	Zfish	PMID:17507405
Biological Process	GO:0021703	locus ceruleus development	bmp2b	IMP	ZFIN:ZDB-GENO-081107-2	Zfish	PMID:10595509
Biological Process	GO:0048762	mesenchymal cell differentiation	BMP2	IDA		Human	PMID:9693150
Biological Process	GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	Bmp2	IMP		Mouse	MGI:MGI:3583399|PMID:15925496
Biological Process	GO:0060485	mesenchyme development	BMP2	IMP		Human	PMID:20890042
Biological Process	GO:0001710	mesodermal cell fate commitment	bmp2b	IGI	ZFIN:ZDB-GENO-980202-1488,ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0032348	negative regulation of aldosterone biosynthetic process	BMP2	IDA		Human	PMID:19584291
Biological Process	GO:0051042	negative regulation of calcium-independent cell-cell adhesion	BMP2	IDA		Human	PMID:16194878
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	BMP2	IEP		Human	PMID:17202865
Biological Process	GO:2000726	negative regulation of cardiac muscle cell differentiation	BMP2	IDA		Human	PMID:18545679
Biological Process	GO:0045786	negative regulation of cell cycle	BMP2	IDA		Human	PMID:11502704
Biological Process	GO:0008285	negative regulation of cell population proliferation	BMP2	IDA		Human	PMID:9187146
Biological Process	GO:0008285	negative regulation of cell population proliferation	BMP2	IDA		Human	PMID:19584291
Biological Process	GO:0008285	negative regulation of cell population proliferation	Bmp2	IGI	MGI:MGI:104903	Mouse	PMID:15925496
Biological Process	GO:2000065	negative regulation of cortisol biosynthetic process	BMP2	IDA		Human	PMID:19584291
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BMP2	IDA		Human	PMID:15254224
Biological Process	GO:0042664	negative regulation of endodermal cell fate specification	bmp2b	IGI	ZFIN:ZDB-GENE-000208-25,ZFIN:ZDB-GENE-980528-2059	Zfish	PMID:16672336
Biological Process	GO:0045599	negative regulation of fat cell differentiation	BMP2	IDA		Human	PMID:23399447
Biological Process	GO:0010629	negative regulation of gene expression	BMP2	IDA		Human	PMID:23399447
Biological Process	GO:0010629	negative regulation of gene expression	BMP2	IDA		Human	PMID:28124060
Biological Process	GO:0010629	negative regulation of gene expression	Bmp2	IDA		Mouse	PMID:15322112
Biological Process	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	BMP2	IDA		Human	PMID:19584291
Biological Process	GO:0043407	negative regulation of MAP kinase activity	BMP2	IDA		Human	PMID:18382765
Biological Process	GO:0051148	negative regulation of muscle cell differentiation	Bmp2	IDA		Mouse	PMID:7798324
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	BMP2	IDA		Human	PMID:18382765
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	BMP2	IGI	UniProtKB:P01137	Human	PMID:28467929
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	Bmp2	IGI	UniProtKB:P37238	Mouse	MGI:MGI:3795340|PMID:18382765
Biological Process	GO:0010894	negative regulation of steroid biosynthetic process	BMP2	IDA		Human	PMID:19584291
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	BMP2	IDA		Human	PMID:9187146
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	BMP2	IDA		Human	PMID:19736317
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bmp2	IMP		Mouse	MGI:MGI:3611958|PMID:16314491
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bmp2	IDA		Mouse	PMID:9585504
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	BMP2	IGI	UniProtKB:P01137	Human	PMID:28467929
Biological Process	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development	BMP2	IDA		Human	PMID:18545679
Biological Process	GO:1901166	neural crest cell migration involved in autonomic nervous system development	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-101112-1	Zfish	PMID:31849612
Biological Process	GO:0022008	neurogenesis	bmp2b	IMP	ZFIN:ZDB-GENO-980202-1071	Zfish	PMID:10529416
Biological Process	GO:0007219	Notch signaling pathway	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0030903	notochord development	bmp2b	IGI	ZFIN:ZDB-GENO-980202-1488,ZFIN:ZDB-MRPHLNO-060130-10,ZFIN:ZDB-MRPHLNO-060130-7,ZFIN:ZDB-MRPHLNO-060130-8,ZFIN:ZDB-MRPHLNO-060130-9	Zfish	PMID:16216234
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Bmp2	IDA		Mouse	PMID:15525533
Biological Process	GO:0001649	osteoblast differentiation	BMP2	IDA		Human	PMID:15150273
Biological Process	GO:0001649	osteoblast differentiation	BMP2	IDA		Human	PMID:22705305
Biological Process	GO:0001649	osteoblast differentiation	BMP2	IDA		Human	PMID:15254224
Biological Process	GO:0001649	osteoblast differentiation	BMP2	IDA		Human	PMID:18436533
Biological Process	GO:0001649	osteoblast differentiation	BMP2	IDA		Human	PMID:20576608
Biological Process	GO:0001649	osteoblast differentiation	BMP2	IDA		Human	PMID:23399447
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IDA		Mouse	PMID:7798324
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IDA		Mouse	PMID:20551513
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IDA		Mouse	PMID:19208758
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IGI	MGI:MGI:1922667	Mouse	PMID:19213727
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IGI	MGI:MGI:99829	Mouse	PMID:15565649
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IGI	MGI:MGI:88182	Mouse	PMID:16109715
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IGI	MGI:MGI:101948	Mouse	PMID:19213727
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IGI	MGI:MGI:96440	Mouse	PMID:19208758
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IGI	MGI:MGI:87986	Mouse	PMID:19208758
Biological Process	GO:0001649	osteoblast differentiation	Bmp2	IDA		Mouse	PMID:19213727
Biological Process	GO:0030316	osteoclast differentiation	BMP2	IMP		Human	PMID:27860183
Biological Process	GO:0042698	ovulation cycle	Bmp2	IEP		Rat	PMID:15283681|RGD:2289021
Biological Process	GO:0061131	pancreas field specification	bmp2b	IDA		Zfish	PMID:24530296
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	BMP2	IDA		Human	PMID:16049014
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	BMP2	IDA		Human	PMID:18184661
Biological Process	GO:0060039	pericardium development	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0043065	positive regulation of apoptotic process	BMP2	IDA		Human	PMID:9187146
Biological Process	GO:0048711	positive regulation of astrocyte differentiation	Bmp2	IDA		Mouse	PMID:10486560
Biological Process	GO:0048711	positive regulation of astrocyte differentiation	Bmp2	IGI	MGI:MGI:99414	Mouse	PMID:15882580
Biological Process	GO:0048711	positive regulation of astrocyte differentiation	Bmp2	IDA		Mouse	PMID:15882580
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	bmp2a	IDA		Zfish	PMID:26341094
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	bmp2b	IDA		Zfish	PMID:26341094
Biological Process	GO:0030501	positive regulation of bone mineralization	BMP2	IDA		Human	PMID:18436533
Biological Process	GO:0030501	positive regulation of bone mineralization	BMP2	IDA		Human	PMID:20576608
Biological Process	GO:0030501	positive regulation of bone mineralization	Bmp2	IDA		Mouse	MGI:MGI:5009350|PMID:20675382
Biological Process	GO:1900159	positive regulation of bone mineralization involved in bone maturation	BMP2	IDA		Human	PMID:16433617
Biological Process	GO:0061036	positive regulation of cartilage development	BMP2	IDA		Human	PMID:3201241
Biological Process	GO:0061036	positive regulation of cartilage development	Bmp2	IDA		Mouse	PMID:10684250
Biological Process	GO:0030335	positive regulation of cell migration	Bmp2	IMP		Mouse	MGI:MGI:5009350|PMID:20675382
Biological Process	GO:0008284	positive regulation of cell population proliferation	BMP2	IMP		Human	PMID:24778011
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	BMP2	IDA		Human	PMID:18382765
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BMP2	IDA		Human	PMID:16049014
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BMP2	IDA		Human	PMID:16243309
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	BMP2	IDA		Human	PMID:17992660
Biological Process	GO:0030858	positive regulation of epithelial cell differentiation	Bmp2	IDA		Mouse	PMID:15525533
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	BMP2	IDA		Human	PMID:20890042
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	BMP2	IMP		Human	PMID:19664780
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	BMP2	IDA		Human	PMID:22540193
Biological Process	GO:0003331	positive regulation of extracellular matrix constituent secretion	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Bmp2	IDA		Mouse	PMID:15175325
Biological Process	GO:0010628	positive regulation of gene expression	BMP2	IDA		Human	PMID:18382765
Biological Process	GO:0010628	positive regulation of gene expression	BMP2	IMP		Human	PMID:23399447
Biological Process	GO:0010628	positive regulation of gene expression	BMP2	IMP		Human	PMID:27860183
Biological Process	GO:0010628	positive regulation of gene expression	BMP2	IDA		Human	PMID:16243309
Biological Process	GO:0010628	positive regulation of gene expression	BMP2	IGI	RNAcentral:URS0000574A2C_9606	Human	PMID:22450430
Biological Process	GO:0010628	positive regulation of gene expression	BMP2	IDA		Human	PMID:22579779
Biological Process	GO:0010628	positive regulation of gene expression	BMP2	IDA		Human	PMID:28124060
Biological Process	GO:0010628	positive regulation of gene expression	BMP2	IDA		Human	PMID:28467929
Biological Process	GO:0010628	positive regulation of gene expression	Bmp2	IDA		Mouse	MGI:MGI:3795340|PMID:18382765
Biological Process	GO:0010628	positive regulation of gene expression	Bmp2	IMP		Mouse	MGI:MGI:3640731|PMID:16730346
Biological Process	GO:0010628	positive regulation of gene expression	Bmp2	IDA		Mouse	PMID:21624478
Biological Process	GO:0043410	positive regulation of MAPK cascade	BMP2	IDA		Human	PMID:22540193
Biological Process	GO:1902895	positive regulation of miRNA transcription	Bmp2	IGI	UniProtKB:P21275	Mouse	MGI:MGI:4939577|PMID:21145505
Biological Process	GO:0050769	positive regulation of neurogenesis	Bmp2	IDA		Rat	PMID:8616889|RGD:8553354
Biological Process	GO:0045666	positive regulation of neuron differentiation	Bmp2	IDA		Mouse	PMID:9786991
Biological Process	GO:0042482	positive regulation of odontogenesis	Bmp2	IDA		Mouse	PMID:7848824
Biological Process	GO:0045778	positive regulation of ossification	BMP2	IDA		Human	PMID:9213002
Biological Process	GO:0045778	positive regulation of ossification	Bmp2	IDA		Mouse	PMID:21324897
Biological Process	GO:0045778	positive regulation of ossification	Bmp2	IDA		Mouse	PMID:15820682
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Bmp2	IMP		Mouse	MGI:MGI:5009350|PMID:20675382
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Bmp2	IDA		Mouse	PMID:16099986
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Bmp2	IDA		Mouse	PMID:15175325
Biological Process	GO:0033690	positive regulation of osteoblast proliferation	Bmp2	IMP		Mouse	MGI:MGI:5009350|PMID:20675382
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	BMP2	IDA		Human	PMID:22540193
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP2	IDA		Human	PMID:16049014
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP2	IDA		Human	PMID:17244894
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP2	IMP		Human	PMID:17992660
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP2	IMP		Human	PMID:19664780
Biological Process	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	BMP2	IGI	UniProtKB:P01137,UniProtKB:P37231	Human	PMID:28467929
Biological Process	GO:0010922	positive regulation of phosphatase activity	BMP2	IDA		Human	PMID:9213002
Biological Process	GO:0032092	positive regulation of protein binding	BMP2	IDA		Human	PMID:16604073
Biological Process	GO:0001934	positive regulation of protein phosphorylation	BMP2	IDA		Human	PMID:17472960
Biological Process	GO:0001934	positive regulation of protein phosphorylation	BMP2	IDA		Human	PMID:8653785
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	BMP2	IDA		Human	PMID:18382765
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	BMP2	IDA		Human	PMID:20427544
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	BMP2	IMP		Human	PMID:24778011
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	Bmp2	IDA		Mouse	MGI:MGI:3795340|PMID:18382765
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BMP2	IDA		Human	PMID:9187146
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BMP2	IDA		Human	PMID:16433617
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BMP2	IDA		Human	PMID:16604073
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BMP2	IGI	UniProtKB:Q6ZVN8	Human	PMID:18326817
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BMP2	IDA		Human	PMID:19736317
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BMP2	IDA		Human	PMID:20890042
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp2	IMP		Mouse	MGI:MGI:4837019|PMID:20890042
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp2	IDA		Mouse	PMID:8769660
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp2	IDA		Mouse	PMID:20042692
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp2	IDA		Mouse	PMID:9769173
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp2	IDA		Mouse	PMID:1468569
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp2	IDA		Mouse	PMID:10391928
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp2	IDA		Rat	PMID:8616889|RGD:8553354
Biological Process	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	BMP2	IDA		Human	PMID:20843790
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	Bmp2	IDA		Mouse	PMID:14627707
Biological Process	GO:0060804	positive regulation of Wnt signaling pathway by BMP signaling pathway	Bmp2	IDA		Mouse	PMID:19213727
Biological Process	GO:0031648	protein destabilization	Bmp2	IGI	MGI:MGI:96396	Mouse	PMID:15322112
Biological Process	GO:0031648	protein destabilization	Bmp2	IDA		Mouse	PMID:15322112
Biological Process	GO:0006468	protein phosphorylation	BMP2	IDA		Human	PMID:22540193
Biological Process	GO:0065003	protein-containing complex assembly	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-050902-2	Zfish	PMID:19377468
Biological Process	GO:0006029	proteoglycan metabolic process	Bmp2	IGI	MGI:MGI:96533	Mouse	PMID:16935278
Biological Process	GO:0006355	regulation of DNA-templated transcription	BMP2	IDA		Human	PMID:15671031
Biological Process	GO:0042487	regulation of odontogenesis of dentin-containing tooth	Bmp2	IGI	MGI:MGI:99604	Mouse	PMID:9244299
Biological Process	GO:0042487	regulation of odontogenesis of dentin-containing tooth	Bmp2	IGI	MGI:MGI:88180	Mouse	PMID:9244299
Biological Process	GO:0009617	response to bacterium	Bmp2	IEP		Mouse	PMID:23012479
Biological Process	GO:0001666	response to hypoxia	Bmp2	IMP	MGI:MGI:1857894	Mouse	PMID:20042692
Biological Process	GO:0009612	response to mechanical stimulus	Bmp2	IEP		Rat	PMID:10404008|RGD:2289026
Biological Process	GO:0032526	response to retinoic acid	Bmp2	IEP		Rat	PMID:8385738|RGD:2289028
Biological Process	GO:0060876	semicircular canal formation	bmp2b	IMP	ZFIN:ZDB-GENO-080731-2	Zfish	PMID:21129728
Biological Process	GO:0048752	semicircular canal morphogenesis	bmp2b	IMP	ZFIN:ZDB-GENO-081224-1	Zfish	PMID:19190757
Biological Process	GO:0048752	semicircular canal morphogenesis	bmp2b	IMP	ZFIN:ZDB-GENO-090609-1	Zfish	PMID:19190757
Biological Process	GO:0048752	semicircular canal morphogenesis	bmp2b	IMP	ZFIN:ZDB-GENO-081107-2	Zfish	PMID:19190757
Biological Process	GO:0060395	SMAD protein signal transduction	BMP2	IDA		Human	PMID:17244894
Biological Process	GO:0021537	telencephalon development	BMP2	IDA		Human	PMID:9187146
Biological Process	GO:0021978	telencephalon regionalization	Bmp2	IGI	MGI:MGI:96785	Mouse	PMID:11719201
Biological Process	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation	Bmp2	IDA		Mouse	PMID:9463347
Biological Process	GO:0006366	transcription by RNA polymerase II	Bmp2	IDA		Mouse	PMID:10391928
Biological Process	GO:0006366	transcription by RNA polymerase II	Bmp2	IMP	MGI:MGI:3583785	Mouse	PMID:16314491
Biological Process	GO:0055015	ventricular cardiac muscle cell development	bmp2b	IMP	ZFIN:ZDB-MRPHLNO-070620-4	Zfish	PMID:17367767
Biological Process	GO:0016055	Wnt signaling pathway	Bmp2	IDA		Mouse	PMID:19213727

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern