Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BMP7
  • Mouse genes Bmp7
  • Rat genes Bmp7
  • Zfish genes bmp7a,bmp7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bmp7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	Bmp7	IDA		Rat	PMID:12927798|RGD:737843
Molecular Function	GO:0042802	identical protein binding	bmp7a	IPI	ZFIN:ZDB-GENE-000208-25	Zfish	PMID:19377468
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:Q03167	Human	PMID:18184661
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P35555	Human	PMID:18339631
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P35556	Human	PMID:18339631
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P14373	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P60411	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:Q5VWX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:Q86Z20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:Q9BUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:Q9BYQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:Q9BYR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:Q8IX30	Human	PMID:33308444
Molecular Function	GO:0005515	protein binding	BMP7	IPI	UniProtKB:P17813	Human	PMID:9872992
Molecular Function	GO:0005515	protein binding	Bmp7	IPI	UniProtKB:Q8CF09	Mouse	PMID:14623234
Molecular Function	GO:0005515	protein binding	Bmp7	IPI	PR:Q3U492	Mouse	PMID:15793581
Molecular Function	GO:0005515	protein binding	Bmp7	IPI	PR:Q8VEA6	Mouse	PMID:14660436
Molecular Function	GO:0005515	protein binding	Bmp7	IPI	UniProtKB:Q9ERN7	Mouse	PMID:15843411
Molecular Function	GO:0005515	protein binding	Bmp7	IPI	PR:P43029	Mouse	PMID:12741987
Molecular Function	GO:0046982	protein heterodimerization activity	bmp7a	IPI	UniProtKB:O13108	Zfish	PMID:19377468
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Bmp7	IDA		Rat	PMID:9626398|RGD:2289041
Cellular Component	GO:0005615	extracellular space	BMP7	IDA		Human	PMID:17977014
Cellular Component	GO:0005615	extracellular space	Bmp7	IDA		Mouse	PMID:12741987
Cellular Component	GO:0005615	extracellular space	Bmp7	IDA		Rat	PMID:18758911|RGD:2301841
Cellular Component	GO:0031982	vesicle	Bmp7	IDA		Rat	PMID:18758911|RGD:2301841
Biological Process	GO:1905069	allantois development	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0036305	ameloblast differentiation	Bmp7	IDA		Mouse	PMID:15525533
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:16854970
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:10049573
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Bmp7	IMP	MGI:MGI:2136986	Mouse	PMID:17878916
Biological Process	GO:0009887	animal organ morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:7590254
Biological Process	GO:0007411	axon guidance	Bmp7	IDA		Mouse	PMID:12741987
Biological Process	GO:0030509	BMP signaling pathway	BMP7	IDA		Human	PMID:16049014
Biological Process	GO:0030509	BMP signaling pathway	BMP7	IMP		Human	PMID:18326817
Biological Process	GO:0030509	BMP signaling pathway	BMP7	IDA		Human	PMID:18436533
Biological Process	GO:0030509	BMP signaling pathway	BMP7	IDA		Human	PMID:20427544
Biological Process	GO:0030509	BMP signaling pathway	Bmp7	IDA		Mouse	PMID:14623234
Biological Process	GO:0030509	BMP signaling pathway	bmp7a	IMP	ZFIN:ZDB-GENO-100415-21	Zfish	PMID:32897189
Biological Process	GO:0030509	BMP signaling pathway	bmp7a	IMP		Zfish	PMID:9676195
Biological Process	GO:0030509	BMP signaling pathway	bmp7a	IMP	ZFIN:ZDB-GENO-050216-1	Zfish	PMID:19377468
Biological Process	GO:0003303	BMP signaling pathway involved in heart jogging	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:9334285
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:11731698
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	Bmp7	IDA		Mouse	PMID:15831470
Biological Process	GO:0048593	camera-type eye morphogenesis	Bmp7	IMP	MGI:MGI:2136986	Mouse	PMID:16154126
Biological Process	GO:0048593	camera-type eye morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:16854970
Biological Process	GO:0048738	cardiac muscle tissue development	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0060411	cardiac septum morphogenesis	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0048468	cell development	Bmp7	IDA		Mouse	PMID:15831470
Biological Process	GO:0008283	cell population proliferation	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:16854970
Biological Process	GO:0071773	cellular response to BMP stimulus	BMP7	IMP		Human	PMID:18326817
Biological Process	GO:0060710	chorio-allantoic fusion	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0007368	determination of left/right symmetry	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:9334285
Biological Process	GO:0048264	determination of ventral identity	bmp7a	IMP	ZFIN:ZDB-GENO-980202-960	Zfish	PMID:11222140
Biological Process	GO:0048264	determination of ventral identity	bmp7a	IMP	ZFIN:ZDB-MRPHLNO-050902-3	Zfish	PMID:16527746
Biological Process	GO:0048264	determination of ventral identity	bmp7a	IDA		Zfish	PMID:11222140
Biological Process	GO:0048264	determination of ventral identity	bmp7a	IMP	ZFIN:ZDB-MRPHLNO-050902-3	Zfish	PMID:11477698
Biological Process	GO:0048264	determination of ventral identity	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:12601179
Biological Process	GO:0048264	determination of ventral identity	bmp7a	IGI	ZFIN:ZDB-MRPHLNO-050902-2,ZFIN:ZDB-MRPHLNO-050902-3	Zfish	PMID:16527746
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:11748837
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:11969259
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp7a	IEP		Zfish	PMID:9676195
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmp7a	IGI	ZFIN:ZDB-GENO-100422-2	Zfish	PMID:11748837
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:10049573
Biological Process	GO:0003143	embryonic heart tube morphogenesis	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:9334285
Biological Process	GO:0030326	embryonic limb morphogenesis	Bmp7	IGI	MGI:MGI:88180	Mouse	PMID:9664686
Biological Process	GO:0030326	embryonic limb morphogenesis	Bmp7	IMP	MGI:MGI:1934010	Mouse	PMID:9664686
Biological Process	GO:0009880	embryonic pattern specification	Bmp7	IMP		Mouse	PMID:10049573
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Bmp7	IMP	MGI:MGI:1934010	Mouse	PMID:9664686
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Bmp7	IGI	MGI:MGI:88180	Mouse	PMID:9664686
Biological Process	GO:0003272	endocardial cushion formation	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0030855	epithelial cell differentiation	Bmp7	IMP	MGI:MGI:2136986	Mouse	PMID:17878916
Biological Process	GO:0001654	eye development	Bmp7	IMP		Mouse	MGI:MGI:3610441|PMID:16154126
Biological Process	GO:0001947	heart looping	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:9334285
Biological Process	GO:0061384	heart trabecula morphogenesis	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0030902	hindbrain development	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0001822	kidney development	Bmp7	IMP	MGI:MGI:2136986	Mouse	PMID:16154126
Biological Process	GO:0021703	locus ceruleus development	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:10595509
Biological Process	GO:1901145	mesenchymal cell apoptotic process involved in nephron morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:9056639
Biological Process	GO:0048762	mesenchymal cell differentiation	BMP7	IDA		Human	PMID:9693150
Biological Process	GO:0060485	mesenchyme development	Bmp7	IMP		Mouse	MGI:MGI:1289719|PMID:9693150
Biological Process	GO:0001707	mesoderm formation	Bmp7	IGI	MGI:MGI:2137520	Mouse	PMID:15843411
Biological Process	GO:0001823	mesonephros development	BMP7	IEP		Human	PMID:18437684
Biological Process	GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	Bmp7	IGI	UniProtKB:P97471	Mouse	MGI:MGI:3623046|PMID:15342483
Biological Process	GO:0072133	metanephric mesenchyme morphogenesis	Bmp7	IGI	UniProtKB:P97471	Mouse	MGI:MGI:3623046|PMID:15342483
Biological Process	GO:0001656	metanephros development	BMP7	IEP		Human	PMID:18437684
Biological Process	GO:0070487	monocyte aggregation	BMP7	IDA		Human	PMID:15100360
Biological Process	GO:0045786	negative regulation of cell cycle	BMP7	IDA		Human	PMID:11502704
Biological Process	GO:0060548	negative regulation of cell death	BMP7	IDA		Human	PMID:12631064
Biological Process	GO:0008285	negative regulation of cell population proliferation	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:16854970
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BMP7	IDA		Human	PMID:15100360
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BMP7	IDA		Human	PMID:17244894
Biological Process	GO:0042664	negative regulation of endodermal cell fate specification	bmp7a	IGI	ZFIN:ZDB-GENE-980526-474,ZFIN:ZDB-GENE-980528-2059	Zfish	PMID:16672336
Biological Process	GO:0072125	negative regulation of glomerular mesangial cell proliferation	BMP7	IDA		Human	PMID:17244894
Biological Process	GO:0043407	negative regulation of MAP kinase activity	BMP7	IDA		Human	PMID:17244894
Biological Process	GO:0072040	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:9056639
Biological Process	GO:0045839	negative regulation of mitotic nuclear division	BMP7	IDA		Human	PMID:17244894
Biological Process	GO:0050768	negative regulation of neurogenesis	Bmp7	IDA		Mouse	PMID:17699604
Biological Process	GO:0045665	negative regulation of neuron differentiation	BMP7	IDA		Human	PMID:16325379
Biological Process	GO:0045665	negative regulation of neuron differentiation	Bmp7	IMP		Mouse	PMID:16325379
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	Bmp7	IGI	MGI:MGI:1099809	Mouse	PMID:16324690
Biological Process	GO:0042326	negative regulation of phosphorylation	BMP7	IDA		Human	PMID:17244894
Biological Process	GO:0060686	negative regulation of prostatic bud formation	Bmp7	IDA		Mouse	PMID:16324690
Biological Process	GO:0072134	nephrogenic mesenchyme morphogenesis	Bmp7	IGI	UniProtKB:P97471	Mouse	MGI:MGI:3623046|PMID:15342483
Biological Process	GO:0021502	neural fold elevation formation	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0048812	neuron projection morphogenesis	BMP7	IDA		Human	PMID:16325379
Biological Process	GO:0048812	neuron projection morphogenesis	Bmp7	IMP		Mouse	PMID:16325379
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Bmp7	IDA		Mouse	PMID:15525533
Biological Process	GO:0007389	pattern specification process	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:7590254
Biological Process	GO:0003344	pericardium morphogenesis	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0060037	pharyngeal system development	Bmp7	IGI	UniProtKB:P49003	Mouse	MGI:MGI:1332253|PMID:10079236
Biological Process	GO:0043065	positive regulation of apoptotic process	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:16854970
Biological Process	GO:0030501	positive regulation of bone mineralization	BMP7	IDA		Human	PMID:18436533
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	BMP7	IMP		Human	PMID:27923061
Biological Process	GO:1905312	positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	Bmp7	IGI	UniProtKB:P21275	Mouse	MGI:MGI:5502250|PMID:23863481
Biological Process	GO:0010942	positive regulation of cell death	Bmp7	IGI	UniProtKB:P97471	Mouse	MGI:MGI:3623046|PMID:15342483
Biological Process	GO:1900006	positive regulation of dendrite development	BMP7	IDA		Human	PMID:11580864
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BMP7	IDA		Human	PMID:14517293
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BMP7	IDA		Human	PMID:15100360
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BMP7	IDA		Human	PMID:16049014
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BMP7	IMP		Human	PMID:27923061
Biological Process	GO:0030858	positive regulation of epithelial cell differentiation	Bmp7	IDA		Mouse	PMID:15525533
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	Bmp7	IGI	UniProtKB:P21275	Mouse	MGI:MGI:5502250|PMID:23863481
Biological Process	GO:0010628	positive regulation of gene expression	BMP7	IDA		Human	PMID:28124060
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	BMP7	IDA		Human	PMID:15100360
Biological Process	GO:1900106	positive regulation of hyaluranon cable assembly	BMP7	IDA		Human	PMID:15100360
Biological Process	GO:0045666	positive regulation of neuron differentiation	Bmp7	IDA		Mouse	PMID:9786991
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	BMP7	IDA		Human	PMID:18436533
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP7	IDA		Human	PMID:16049014
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP7	IDA		Human	PMID:17244894
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP7	IDA		Human	PMID:19736306
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	BMP7	IDA		Human	PMID:9311995
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	BMP7	IDA		Human	PMID:19736306
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	BMP7	IDA		Human	PMID:20427544
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp7	IGI	MGI:MGI:1919200	Mouse	PMID:16801560
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bmp7	IGI	MGI:MGI:1276116	Mouse	PMID:16801560
Biological Process	GO:0036342	post-anal tail morphogenesis	bmp7a	IMP	ZFIN:ZDB-GENO-980202-1043	Zfish	PMID:21610036
Biological Process	GO:0034504	protein localization to nucleus	BMP7	IDA		Human	PMID:17244894
Biological Process	GO:0065003	protein-containing complex assembly	bmp7a	IMP	ZFIN:ZDB-GENO-050216-1	Zfish	PMID:19377468
Biological Process	GO:0060687	regulation of branching involved in prostate gland morphogenesis	Bmp7	IMP	MGI:MGI:2136986	Mouse	PMID:16324690
Biological Process	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	BMP7	IDA		Human	PMID:16049014
Biological Process	GO:0042325	regulation of phosphorylation	Bmp7	IMP		Rat	PMID:12927798|RGD:737843
Biological Process	GO:0032355	response to estradiol	Bmp7	IEP		Rat	PMID:15680359|RGD:1643594
Biological Process	GO:0043434	response to peptide hormone	Bmp7	IEP		Rat	PMID:15728789|RGD:2289040
Biological Process	GO:0033280	response to vitamin D	Bmp7	IEP		Rat	PMID:17554252|RGD:2289035
Biological Process	GO:0007435	salivary gland morphogenesis	Bmp7	IMP	MGI:MGI:1857654	Mouse	PMID:11731698
Biological Process	GO:0060395	SMAD protein signal transduction	BMP7	IDA		Human	PMID:17244894
Biological Process	GO:0043401	steroid hormone mediated signaling pathway	BMP7	IMP		Human	PMID:17244894
Biological Process	GO:0035239	tube morphogenesis	Bmp7	IDA		Mouse	PMID:15831470
Biological Process	GO:0001657	ureteric bud development	Bmp7	IMP		Mouse	MGI:MGI:1289719|PMID:9693150

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern