Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BMPR1B
  • Mouse genes Bmpr1b
  • Rat genes Bmpr1b
  • Zfish genes bmpr1ba,bmpr1bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bmpr1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	BMPR1B	IDA		Human	PMID:12065756
Molecular Function	GO:0036122	BMP binding	Bmpr1b	IDA		Mouse	PMID:11714695
Molecular Function	GO:0098821	BMP receptor activity	Bmpr1b	IDA		Mouse	PMID:11714695
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:Q16671	Human	PMID:10854429
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:Q8N6C5	Human	PMID:11266516
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:O60749	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:Q16671	Human	PMID:11549681
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:P43026	Human	PMID:16127465
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:P12643	Human	PMID:18184661
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:P12643	Human	PMID:19229295
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:P43026	Human	PMID:19229295
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:P43026	Human	PMID:21976273
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:Q13873	Human	PMID:21976273
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:P43026	Human	PMID:24098149
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:Q30201	Human	PMID:24904118
Molecular Function	GO:0005515	protein binding	BMPR1B	IPI	UniProtKB:Q8IX30	Human	PMID:33308444
Molecular Function	GO:0005515	protein binding	Bmpr1b	IPI	UniProtKB:O88307	Mouse	MGI:MGI:5704270|PMID:26584636
Molecular Function	GO:0005515	protein binding	Bmpr1b	IPI	UniProtKB:O35182	Mouse	MGI:MGI:5508676|PMID:23455153
Molecular Function	GO:0005515	protein binding	Bmpr1b	IPI	UniProtKB:O35182	Mouse	MGI:MGI:5512842|PMID:17118358
Molecular Function	GO:0005515	protein binding	Bmpr1b	IPI	PR:Q922H7	Mouse	PMID:15239668
Molecular Function	GO:0004674	protein serine/threonine kinase activity	BMPR1B	IDA		Human	PMID:12065756
Molecular Function	GO:0046332	SMAD binding	BMPR1B	IDA		Human	PMID:12065756
Molecular Function	GO:0005025	transforming growth factor beta receptor activity, type I	Bmpr1b	IMP		Mouse	PMID:11376112
Molecular Function	GO:0004675	transmembrane receptor protein serine/threonine kinase activity	Bmpr1b	IMP		Mouse	MGI:MGI:6827203|PMID:14523231
Cellular Component	GO:0030425	dendrite	Bmpr1b	IDA		Rat	PMID:21185359|RGD:5129479
Cellular Component	GO:0043025	neuronal cell body	Bmpr1b	IDA		Rat	PMID:21185359|RGD:5129479
Cellular Component	GO:0005886	plasma membrane	Bmpr1b	IDA		Mouse	MGI:MGI:5751671|PMID:24129431
Biological Process	GO:0030509	BMP signaling pathway	BMPR1B	IDA		Human	PMID:18436533
Biological Process	GO:0030509	BMP signaling pathway	Bmpr1b	IDA		Mouse	MGI:MGI:5751671|PMID:24129431
Biological Process	GO:0030509	BMP signaling pathway	Bmpr1b	IDA		Mouse	PMID:11714695
Biological Process	GO:0030509	BMP signaling pathway	Bmpr1b	IGI	MGI:MGI:1916835	Mouse	PMID:16604073
Biological Process	GO:0030509	BMP signaling pathway	Bmpr1b	IMP		Mouse	PMID:11376112
Biological Process	GO:0030509	BMP signaling pathway	Bmpr1b	IGI	MGI:MGI:88177	Mouse	PMID:16604073
Biological Process	GO:0030509	BMP signaling pathway	Bmpr1b	IGI	MGI:MGI:95690	Mouse	PMID:16049014
Biological Process	GO:0030509	BMP signaling pathway	Bmpr1b	IGI	MGI:MGI:95689	Mouse	PMID:16049014
Biological Process	GO:0030509	BMP signaling pathway	Bmpr1b	IGI	MGI:MGI:109452	Mouse	PMID:16604073
Biological Process	GO:0030509	BMP signaling pathway	bmpr1bb	IGI	ZFIN:ZDB-MRPHLNO-090609-2,ZFIN:ZDB-MRPHLNO-090609-3,ZFIN:ZDB-MRPHLNO-090609-5,ZFIN:ZDB-MRPHLNO-090610-1	Zfish	PMID:19377468
Biological Process	GO:0030509	BMP signaling pathway	bmpr1bb	IMP	ZFIN:ZDB-GENO-111220-2	Zfish	PMID:21775673
Biological Process	GO:0030509	BMP signaling pathway	bmpr1ba	IGI	ZFIN:ZDB-MRPHLNO-090609-2,ZFIN:ZDB-MRPHLNO-090609-3,ZFIN:ZDB-MRPHLNO-090609-5,ZFIN:ZDB-MRPHLNO-090610-1	Zfish	PMID:19377468
Biological Process	GO:0060348	bone development	Bmpr1b	IMP	MGI:MGI:3696052	Mouse	PMID:20551513
Biological Process	GO:0043010	camera-type eye development	Bmpr1b	IGI	MGI:MGI:1338938	Mouse	PMID:15673568
Biological Process	GO:0001502	cartilage condensation	Bmpr1b	IMP	MGI:MGI:2158498	Mouse	PMID:10631181
Biological Process	GO:0030154	cell differentiation	Bmpr1b	IMP		Mouse	PMID:12117821
Biological Process	GO:0071773	cellular response to BMP stimulus	BMPR1B	IMP		Human	PMID:18326817
Biological Process	GO:0071363	cellular response to growth factor stimulus	Bmpr1b	IDA		Mouse	MGI:MGI:5751671|PMID:24129431
Biological Process	GO:0021953	central nervous system neuron differentiation	Bmpr1b	IGI	MGI:MGI:1338938	Mouse	PMID:15469980
Biological Process	GO:0002062	chondrocyte differentiation	Bmpr1b	IMP		Mouse	MGI:MGI:5522580|PMID:24098149
Biological Process	GO:0002062	chondrocyte differentiation	Bmpr1b	IGI	MGI:MGI:1927616	Mouse	PMID:18363966
Biological Process	GO:0002062	chondrocyte differentiation	Bmpr1b	IGI	MGI:MGI:95688	Mouse	PMID:18363966
Biological Process	GO:0048263	determination of dorsal identity	bmpr1ba	IMP	ZFIN:ZDB-GENO-980202-960	Zfish	PMID:11222140
Biological Process	GO:0009953	dorsal/ventral pattern formation	Bmpr1b	IGI	MGI:MGI:1338938	Mouse	PMID:15673568
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmpr1bb	IGI	ZFIN:ZDB-MRPHLNO-090609-2,ZFIN:ZDB-MRPHLNO-090609-3,ZFIN:ZDB-MRPHLNO-090610-1	Zfish	PMID:19377468
Biological Process	GO:0009953	dorsal/ventral pattern formation	bmpr1ba	IGI	ZFIN:ZDB-MRPHLNO-090609-2,ZFIN:ZDB-MRPHLNO-090609-3,ZFIN:ZDB-MRPHLNO-090609-5	Zfish	PMID:19377468
Biological Process	GO:0001654	eye development	Bmpr1b	IMP		Mouse	PMID:12117821
Biological Process	GO:0042078	germ-line stem cell division	bmpr1bb	IMP	ZFIN:ZDB-GENO-111220-2	Zfish	PMID:21775673
Biological Process	GO:0006954	inflammatory response	Bmpr1b	IEP		Mouse	MGI:MGI:3693397|PMID:12151307
Biological Process	GO:0001649	osteoblast differentiation	BMPR1B	IMP		Human	PMID:28214897
Biological Process	GO:0001649	osteoblast differentiation	Bmpr1b	IDA		Mouse	PMID:20551513
Biological Process	GO:0001550	ovarian cumulus expansion	Bmpr1b	IMP		Mouse	MGI:MGI:2136692|PMID:11416163
Biological Process	GO:0042698	ovulation cycle	Bmpr1b	IMP		Mouse	MGI:MGI:2136692|PMID:11416163
Biological Process	GO:0030501	positive regulation of bone mineralization	BMPR1B	IMP		Human	PMID:18436533
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Bmpr1b	IGI	MGI:MGI:1927616	Mouse	PMID:18363966
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Bmpr1b	IGI	MGI:MGI:95484	Mouse	PMID:18363966
Biological Process	GO:0010628	positive regulation of gene expression	BMPR1B	IMP		Human	PMID:28214897
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	BMPR1B	IMP		Human	PMID:18436533
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BMPR1B	IMP		Human	PMID:18326817
Biological Process	GO:0006468	protein phosphorylation	BMPR1B	IDA		Human	PMID:12065756
Biological Process	GO:0060041	retina development in camera-type eye	Bmpr1b	IMP	MGI:MGI:2158497	Mouse	PMID:12654290
Biological Process	GO:0031290	retinal ganglion cell axon guidance	Bmpr1b	IMP	MGI:MGI:2158497	Mouse	PMID:12654290
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Bmpr1b	IGI	MGI:MGI:1346865	Mouse	PMID:18363966
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Bmpr1b	IGI	MGI:MGI:1927616	Mouse	PMID:18363966
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Bmpr1b	IGI	MGI:MGI:95688	Mouse	PMID:18363966

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern