Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BNIP3
  • Mouse genes Bnip3
  • Rat genes Bnip3
  • Zfish genes bnip3,bnip4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bnip3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051020	GTPase binding	BNIP3	IPI	UniProtKB:O60313	Human	PMID:20436456
Molecular Function	GO:0042802	identical protein binding	BNIP3	IPI	UniProtKB:Q12983	Human	PMID:10381623
Molecular Function	GO:0042802	identical protein binding	BNIP3	IPI	UniProtKB:Q12983	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	BNIP3	IPI	UniProtKB:Q12983	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	BNIP3	IPI	UniProtKB:Q12983	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	BNIP3	IPI	UniProtKB:Q12983	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Bnip3	IPI	PR:O55003	Mouse	PMID:22044588
Molecular Function	GO:0042802	identical protein binding	Bnip3	IPI	RGD:620800	Rat	PMID:25436615|RGD:11561967
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:10381623
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P03247	Human	PMID:10381623
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P10415	Human	PMID:10381623
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9UMX3	Human	PMID:15868100
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P17152	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q5ZSD5	Human	PMID:17360363
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P42765	Human	PMID:18371312
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60313	Human	PMID:20436456
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q8TC71	Human	PMID:22292033
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P17152	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q5T700	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q86UP2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q969F0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9BXN2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P17152	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q8NI37	Human	PMID:27499296
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P17152	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q8NI37	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O00559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O15432	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O60238	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:O95484	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P05981	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P07766	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P17152	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P38484	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P78383	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q04941	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q12982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q15436	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q5T700	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q6P5S7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q6UW68	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q86UP2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q86WK6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q8NI37	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q92520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96CE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96D05-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96HJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96IK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q96MV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9BRK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9BVX2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9BXN2-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9BZL3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9H1V8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9H2S6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9HBV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9Y225-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P03247	Human	PMID:7954800
Molecular Function	GO:0005515	protein binding	BNIP3	IPI	UniProtKB:P10415	Human	PMID:7954800
Molecular Function	GO:0005515	protein binding	Bnip3	IPI	UniProtKB:P10417	Mouse	MGI:MGI:3796473|PMID:18281291
Molecular Function	GO:0005515	protein binding	Bnip3	IPI	RGD:621575	Rat	PMID:25436615|RGD:11561967
Molecular Function	GO:0042803	protein homodimerization activity	BNIP3	IDA		Human	PMID:10381623
Molecular Function	GO:0042803	protein homodimerization activity	BNIP3	IDA		Human	PMID:9396766
Cellular Component	GO:0005737	cytoplasm	Bnip3	IDA		Rat	PMID:14972662|RGD:2314028
Cellular Component	GO:0030425	dendrite	Bnip3	IDA		Rat	PMID:14972662|RGD:2314028
Cellular Component	GO:0031966	mitochondrial membrane	BNIP3	IDA		Human	PMID:10891486
Cellular Component	GO:0031966	mitochondrial membrane	BNIP3	IMP		Human	PMID:9396766
Cellular Component	GO:0031966	mitochondrial membrane	Bnip3	IDA		Mouse	MGI:MGI:3687820|PMID:10891486
Cellular Component	GO:0005741	mitochondrial outer membrane	BNIP3	IDA		Human	PMID:10891486
Cellular Component	GO:0005741	mitochondrial outer membrane	BNIP3	IDA		Human	PMID:22292033
Cellular Component	GO:0005739	mitochondrion	BNIP3	IDA		Human	PMID:18371312
Cellular Component	GO:0005739	mitochondrion	BNIP3	IDA		Human	PMID:7954800
Cellular Component	GO:0005739	mitochondrion	BNIP3	IDA		Human	PMID:9396766
Cellular Component	GO:0005739	mitochondrion	Bnip3	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Bnip3	IDA		Rat	PMID:17980495|RGD:11561965
Cellular Component	GO:0005635	nuclear envelope	BNIP3	IDA		Human	PMID:7954800
Cellular Component	GO:0005654	nucleoplasm	Bnip3	IDA		Rat	PMID:14972662|RGD:2314028
Cellular Component	GO:0005634	nucleus	Bnip3	IDA		Rat	PMID:14972662|RGD:2314028
Cellular Component	GO:0014069	postsynaptic density	Bnip3	IDA		Mouse	PMID:17114649
Biological Process	GO:0048102	autophagic cell death	Bnip3	IMP		Rat	PMID:19539716|RGD:5128797
Biological Process	GO:0050873	brown fat cell differentiation	Bnip3	IDA		Mouse	PMID:18492766
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	Bnip3	IMP		Rat	PMID:12226479|RGD:632019
Biological Process	GO:0008219	cell death	Bnip3	IDA		Rat	PMID:14972662|RGD:2314028
Biological Process	GO:0071279	cellular response to cobalt ion	BNIP3	IMP		Human	PMID:20436456
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Bnip3	IMP		Rat	PMID:19539716|RGD:5128797
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Bnip3	IEP		Rat	PMID:28661226|RGD:155260328
Biological Process	GO:0071456	cellular response to hypoxia	BNIP3	IGI	UniProtKB:O60238	Human	PMID:19273585
Biological Process	GO:0071456	cellular response to hypoxia	BNIP3	IMP		Human	PMID:20436456
Biological Process	GO:0071456	cellular response to hypoxia	Bnip3	IEP		Rat	PMID:17379825|RGD:9685412
Biological Process	GO:0071260	cellular response to mechanical stimulus	BNIP3	IEP		Human	PMID:19593445
Biological Process	GO:0021987	cerebral cortex development	Bnip3	IEP		Rat	PMID:16765336|RGD:11561980
Biological Process	GO:0051607	defense response to virus	BNIP3	IDA		Human	PMID:9973195
Biological Process	GO:0140507	granzyme-mediated programmed cell death signaling pathway	BNIP3	IDA		Human	PMID:9396766
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	Bnip3	IMP		Mouse	PMID:16954213
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	Bnip3	IGI	MGI:MGI:96224	Mouse	PMID:16954213
Biological Process	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia	BNIP3	IMP		Human	PMID:20436456
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	BNIP3	IDA		Human	PMID:20436456
Biological Process	GO:0097345	mitochondrial outer membrane permeabilization	BNIP3	IDA		Human	PMID:18371312
Biological Process	GO:0035694	mitochondrial protein catabolic process	BNIP3	IMP		Human	PMID:22292033
Biological Process	GO:0043066	negative regulation of apoptotic process	Bnip3	IGI	UniProtKB:Q61221	Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0060548	negative regulation of cell death	BNIP3	IGI	UniProtKB:O60238	Human	PMID:19273585
Biological Process	GO:0045837	negative regulation of membrane potential	BNIP3	IDA		Human	PMID:10891486
Biological Process	GO:0010637	negative regulation of mitochondrial fusion	BNIP3	IDA		Human	PMID:20436456
Biological Process	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process	Bnip3	IMP		Rat	PMID:17980495|RGD:11561965
Biological Process	GO:0010917	negative regulation of mitochondrial membrane potential	Bnip3	IMP		Rat	PMID:17980495|RGD:11561965
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	Bnip3	IGI	UniProtKB:Q61221	Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0051402	neuron apoptotic process	Bnip3	IDA		Rat	PMID:14972662|RGD:2314028
Biological Process	GO:0048709	oligodendrocyte differentiation	Bnip3	IEP		Rat	PMID:12787069|RGD:631874
Biological Process	GO:0043065	positive regulation of apoptotic process	BNIP3	IDA		Human	PMID:10381623
Biological Process	GO:0043065	positive regulation of apoptotic process	BNIP3	IDA		Human	PMID:9973195
Biological Process	GO:0043065	positive regulation of apoptotic process	Bnip3	IMP		Rat	PMID:16645637|RGD:11561983
Biological Process	GO:0043065	positive regulation of apoptotic process	Bnip3	IMP		Rat	PMID:17980495|RGD:11561965
Biological Process	GO:1903599	positive regulation of autophagy of mitochondrion	Bnip3	IMP		Rat	PMID:23698117|RGD:11561968
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	Bnip3	IDA		Rat	PMID:23028672|RGD:10047368
Biological Process	GO:0016239	positive regulation of macroautophagy	BNIP3	IGI	UniProtKB:O60238	Human	PMID:19273585
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	Bnip3	IMP		Rat	PMID:25489073|RGD:11561978
Biological Process	GO:0090141	positive regulation of mitochondrial fission	BNIP3	IDA		Human	PMID:20436456
Biological Process	GO:0010940	positive regulation of necrotic cell death	Bnip3	IMP		Rat	PMID:25489073|RGD:11561978
Biological Process	GO:0043068	positive regulation of programmed cell death	BNIP3	IDA		Human	PMID:10891486
Biological Process	GO:0043243	positive regulation of protein-containing complex disassembly	BNIP3	IDA		Human	PMID:20436456
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	BNIP3	IDA		Human	PMID:20436456
Biological Process	GO:0072593	reactive oxygen species metabolic process	BNIP3	IDA		Human	PMID:10891486
Biological Process	GO:1903715	regulation of aerobic respiration	Bnip3	IMP		Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	BNIP3	IDA		Human	PMID:10891486
Biological Process	GO:0010821	regulation of mitochondrion organization	Bnip3	IMP		Mouse	MGI:MGI:3796473|PMID:18281291
Biological Process	GO:0048678	response to axon injury	Bnip3	IEP		Rat	PMID:22639046|RGD:14398458
Biological Process	GO:0009617	response to bacterium	Bnip3	IEP		Mouse	PMID:23012479
Biological Process	GO:0055093	response to hyperoxia	Bnip3	IEP		Rat	PMID:20157446|RGD:5128796
Biological Process	GO:0001666	response to hypoxia	Bnip3	IDA		Rat	PMID:14972662|RGD:2314028
Biological Process	GO:0090649	response to oxygen-glucose deprivation	Bnip3	IEP		Rat	PMID:22639046|RGD:14398458
Biological Process	GO:1901998	toxin transport	Bnip3	IMP		Mouse	PMID:23716698

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern