Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BPIFA1
  • Mouse genes Bpifa1
  • Rat genes Bpifa1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bpifa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:A0A0C4DGQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:A8MUP2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:O00241-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:O14770-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:O43447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:O43711	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P08631-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P0CG20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P12035	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P17482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P27658	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P28676	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P35680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P41970	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P53672	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:P78337	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q01085-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q14D33	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q6NZ36-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q7L2R6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q7Z3B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q8TAE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q8WU58	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q92734	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q96LI6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q96N21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q96NU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q99706	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q99743	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9BRG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9BTL3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9BV90	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9BVN2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9H596	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9HBE1-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9NQB0-10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9NRY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9NXW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9UBV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9UHP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BPIFA1	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Cellular Component	GO:0005576	extracellular region	BPIFA1	IDA		Human	PMID:11425234
Cellular Component	GO:0005615	extracellular space	BPIFA1	IDA		Human	PMID:21805676
Cellular Component	GO:0005615	extracellular space	BPIFA1	IDA		Human	PMID:24124190
Cellular Component	GO:0005902	microvillus	Bpifa1	IDA		Rat	PMID:11821380|RGD:625372
Biological Process	GO:0019731	antibacterial humoral response	BPIFA1	IDA		Human	PMID:23499554
Biological Process	GO:0019731	antibacterial humoral response	Bpifa1	IMP		Mouse	MGI:MGI:5484728|PMID:23499554
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	BPIFA1	IEP		Human	PMID:21805676
Biological Process	GO:0051607	defense response to virus	BPIFA1	IEP		Human	PMID:21805676
Biological Process	GO:0002395	immune response in nasopharyngeal-associated lymphoid tissue	BPIFA1	IEP		Human	PMID:21805676
Biological Process	GO:0045087	innate immune response	BPIFA1	IDA		Human	PMID:23499554
Biological Process	GO:0045087	innate immune response	Bpifa1	IMP		Mouse	MGI:MGI:5484728|PMID:23499554
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	BPIFA1	IDA		Human	PMID:24124190
Biological Process	GO:1900229	negative regulation of single-species biofilm formation in or on host organism	BPIFA1	IMP		Human	PMID:23499554
Biological Process	GO:1900229	negative regulation of single-species biofilm formation in or on host organism	Bpifa1	IMP		Mouse	MGI:MGI:5484728|PMID:23499554
Biological Process	GO:1902305	regulation of sodium ion transmembrane transport	BPIFA1	IDA		Human	PMID:24124190
Biological Process	GO:0043129	surfactant homeostasis	BPIFA1	IDA		Human	PMID:23499554

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern