Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BRCA1
  • Mouse genes Brca1
  • Rat genes Brca1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Brca1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Brca1	IDA		Rat	PMID:15574597|RGD:9586065
Molecular Function	GO:0003684	damaged DNA binding	Brca1	IDA		Mouse	PMID:11934988
Molecular Function	GO:0019899	enzyme binding	BRCA1	IPI	UniProtKB:P11388	Human	PMID:15965487
Molecular Function	GO:0042802	identical protein binding	BRCA1	IPI	UniProtKB:P38398	Human	PMID:29656893
Molecular Function	GO:0042802	identical protein binding	BRCA1	IPI	UniProtKB:P38398	Human	PMID:34591612
Molecular Function	GO:0042802	identical protein binding	BRCA1	IPI	UniProtKB:P38398	Human	PMID:8944023
Molecular Function	GO:0002039	p53 binding	BRCA1	IDA		Human	PMID:15571721
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:10477523
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P06400	Human	PMID:10518542
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P55072	Human	PMID:10855792
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9GZX5	Human	PMID:11090615
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:11301010
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q8WX92	Human	PMID:11739404
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99708	Human	PMID:11739404
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P61969	Human	PMID:11751867
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:O14757	Human	PMID:11836499
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q14683	Human	PMID:11877377
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P51587	Human	PMID:12242698
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q06609	Human	PMID:12242698
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:O15360	Human	PMID:12354784
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P16104	Human	PMID:12419185
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q14676	Human	PMID:12607005
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q14192	Human	PMID:14550570
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:14576433
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q16666	Human	PMID:14654789
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9UHK0	Human	PMID:15107825
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:15125843
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:15133502
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:15265711
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P03372	Human	PMID:15674350
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P11388	Human	PMID:15965487
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q13085	Human	PMID:16326698
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q6PJG6	Human	PMID:16452482
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P24385	Human	PMID:17334399
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P36873	Human	PMID:17511879
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P62136	Human	PMID:17511879
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P62140	Human	PMID:17511879
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P24864	Human	PMID:17525332
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q12888	Human	PMID:17525332
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q14676	Human	PMID:17525332
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q6NZY4	Human	PMID:17525332
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q6UWZ7	Human	PMID:17525340
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q96RL1	Human	PMID:17525340
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99708	Human	PMID:17525340
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:17525340
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:17581638
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q6UWZ7	Human	PMID:17643121
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q96RL1-1	Human	PMID:17643121
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:17873885
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P16104	Human	PMID:18001824
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q12888	Human	PMID:18001824
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P16104	Human	PMID:18001825
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99708	Human	PMID:18285836
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:18285836
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99708	Human	PMID:18716619
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q92560	Human	PMID:19117993
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q6UWZ7	Human	PMID:19261748
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q86YC2	Human	PMID:19369211
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99708	Human	PMID:19369211
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:19369211
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:19369211
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P61956	Human	PMID:20016594
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P63165	Human	PMID:20016594
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P61956	Human	PMID:20016603
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q8N163	Human	PMID:20160719
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q04323	Human	PMID:20351172
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:21240188
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P78347	Human	PMID:21407215
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q15004	Human	PMID:21673012
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q92731	Human	PMID:21951318
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P10809	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q14192	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:O75330	Human	PMID:22110403
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:22110403
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P16104	Human	PMID:22193777
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q86YC2	Human	PMID:22193777
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:22792074
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q12888	Human	PMID:22884692
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q61188	Human	PMID:23624935
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:23680151
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q86YC2	Human	PMID:26649820
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P49959,UniProtKB:Q99708,UniProtKB:Q9NVH0	Human	PMID:26807646
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P28715	Human	PMID:26833090
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q86YC2	Human	PMID:28319063
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q12888	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q14676	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q6UWZ7	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q86YC2	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q96RL1	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99708	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q13085	Human	PMID:29899443
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P03372	Human	PMID:31527615
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q6UWZ7	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q96RL1	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q96SB3	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99708	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q9BX63	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99728	Human	PMID:8944023
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P52292	Human	PMID:9497340
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q7Z569	Human	PMID:9497340
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q92560	Human	PMID:9528852
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q08211	Human	PMID:9662397
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:P51587	Human	PMID:9774970
Molecular Function	GO:0005515	protein binding	BRCA1	IPI	UniProtKB:Q99708	Human	PMID:9811458
Molecular Function	GO:0005515	protein binding	Brca1	IPI	RGD:3959	Rat	PMID:19074549|RGD:10059411
Molecular Function	GO:0003723	RNA binding	BRCA1	IDA		Human	PMID:12419249
Molecular Function	GO:0070063	RNA polymerase binding	BRCA1	IDA		Human	PMID:9662397
Molecular Function	GO:0000976	transcription cis-regulatory region binding	BRCA1	IDA		Human	PMID:20820192
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Brca1	IDA		Mouse	MGI:MGI:5009779|PMID:20820192
Molecular Function	GO:0003713	transcription coactivator activity	BRCA1	IMP		Human	PMID:9662397
Molecular Function	GO:0031625	ubiquitin protein ligase binding	BRCA1	IPI	UniProtKB:P61086	Human	PMID:17873885
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BRCA1	IDA		Human	PMID:12890688
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BRCA1	IDA		Human	PMID:17349954
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BRCA1	IDA		Human	PMID:19117993
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BRCA1	IDA		Human	PMID:20351172
Cellular Component	GO:0070531	BRCA1-A complex	BRCA1	IDA		Human	PMID:17525340
Cellular Component	GO:0070531	BRCA1-A complex	BRCA1	IDA		Human	PMID:17525341
Cellular Component	GO:0070531	BRCA1-A complex	BRCA1	IDA		Human	PMID:17525342
Cellular Component	GO:0070531	BRCA1-A complex	BRCA1	IDA		Human	PMID:19261748
Cellular Component	GO:0070531	BRCA1-A complex	BRCA1	IDA		Human	PMID:19261749
Cellular Component	GO:0070532	BRCA1-B complex	BRCA1	IPI		Human	PMID:16391231
Cellular Component	GO:0031436	BRCA1-BARD1 complex	BRCA1	IPI		Human	PMID:11573085
Cellular Component	GO:0031436	BRCA1-BARD1 complex	BRCA1	IDA		Human	PMID:12890688
Cellular Component	GO:0031436	BRCA1-BARD1 complex	BRCA1	IDA		Human	PMID:15265711
Cellular Component	GO:0031436	BRCA1-BARD1 complex	BRCA1	IDA		Human	PMID:19117993
Cellular Component	GO:0031436	BRCA1-BARD1 complex	BRCA1	IDA		Human	PMID:20351172
Cellular Component	GO:0070533	BRCA1-C complex	BRCA1	IPI		Human	PMID:16391231
Cellular Component	GO:0005694	chromosome	Brca1	IDA		Mouse	MGI:MGI:5465514|PMID:23039116
Cellular Component	GO:0005694	chromosome	Brca1	IDA		Mouse	MGI:MGI:5319701|PMID:22549958
Cellular Component	GO:0000793	condensed chromosome	Brca1	IDA		Mouse	PMID:12913077
Cellular Component	GO:0000794	condensed nuclear chromosome	Brca1	IDA		Mouse	PMID:20551173
Cellular Component	GO:0000794	condensed nuclear chromosome	Brca1	IDA		Mouse	PMID:26490168
Cellular Component	GO:0005737	cytoplasm	BRCA1	IDA		Human	PMID:20160719
Cellular Component	GO:0005737	cytoplasm	Brca1	IDA		Mouse	PMID:11172592
Cellular Component	GO:1990391	DNA repair complex	BRCA1	IPI		Human	PMID:19369211
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	BRCA1	IDA		Human	PMID:9008167
Cellular Component	GO:0000800	lateral element	BRCA1	IDA		Human	PMID:9774970
Cellular Component	GO:0001673	male germ cell nucleus	Brca1	IDA		Mouse	PMID:31839538
Cellular Component	GO:0005759	mitochondrial matrix	Brca1	IDA		Rat	PMID:15591126|RGD:1599499
Cellular Component	GO:0016604	nuclear body	BRCA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000152	nuclear ubiquitin ligase complex	BRCA1	IDA		Human	PMID:14636569
Cellular Component	GO:0005654	nucleoplasm	BRCA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	BRCA1	IDA		Human	PMID:14636569
Cellular Component	GO:0005634	nucleus	BRCA1	IDA		Human	PMID:17525340
Cellular Component	GO:0005634	nucleus	BRCA1	IDA		Human	PMID:17643121
Cellular Component	GO:0005634	nucleus	BRCA1	IDA		Human	PMID:20160719
Cellular Component	GO:0005634	nucleus	BRCA1	IDA		Human	PMID:26833090
Cellular Component	GO:0005634	nucleus	BRCA1	IDA		Human	PMID:9342365
Cellular Component	GO:0005634	nucleus	BRCA1	IDA		Human	PMID:23855721
Cellular Component	GO:0005886	plasma membrane	BRCA1	IDA		Human	PMID:21282464
Cellular Component	GO:0032991	protein-containing complex	BRCA1	IDA		Human	PMID:9774970
Cellular Component	GO:1990904	ribonucleoprotein complex	BRCA1	IDA		Human	PMID:18809582
Cellular Component	GO:0001741	XY body	Brca1	IDA		Mouse	PMID:31839538
Biological Process	GO:0007420	brain development	Brca1	IEP		Rat	PMID:12605402|RGD:634640
Biological Process	GO:0071681	cellular response to indole-3-methanol	BRCA1	IDA		Human	PMID:10868478
Biological Process	GO:0071479	cellular response to ionizing radiation	BRCA1	IMP		Human	PMID:14636569
Biological Process	GO:0071356	cellular response to tumor necrosis factor	BRCA1	IMP		Human	PMID:23415688
Biological Process	GO:0007098	centrosome cycle	Brca1	IGI	MGI:MGI:107799	Mouse	PMID:15123655
Biological Process	GO:0043009	chordate embryonic development	Brca1	IMP	MGI:MGI:1930613	Mouse	PMID:9171368
Biological Process	GO:0007059	chromosome segregation	BRCA1	IMP		Human	PMID:15965487
Biological Process	GO:0006974	DNA damage response	Brca1	IMP	MGI:MGI:3696057	Mouse	PMID:23271346
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	Brca1	IDA		Mouse	PMID:12419249
Biological Process	GO:0006302	double-strand break repair	BRCA1	IMP		Human	PMID:17525340
Biological Process	GO:0006302	double-strand break repair	BRCA1	IMP		Human	PMID:17643121
Biological Process	GO:0006302	double-strand break repair	BRCA1	IMP		Human	PMID:19261748
Biological Process	GO:0006302	double-strand break repair	BRCA1	IDA		Human	PMID:22186889
Biological Process	GO:0006302	double-strand break repair	Brca1	IMP		Mouse	MGI:MGI:5545964|PMID:22186889
Biological Process	GO:0000724	double-strand break repair via homologous recombination	BRCA1	IDA		Human	PMID:17349954
Biological Process	GO:0000724	double-strand break repair via homologous recombination	BRCA1	IDA		Human	PMID:28398198
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	BRCA1	IDA		Human	PMID:14654789
Biological Process	GO:0051179	localization	BRCA1	IDA		Human	PMID:9008167
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	BRCA1	IMP		Human	PMID:17525340
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	BRCA1	IMP		Human	PMID:17643121
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	BRCA1	IMP		Human	PMID:19261748
Biological Process	GO:0044818	mitotic G2/M transition checkpoint	Brca1	IMP		Mouse	PMID:15254237
Biological Process	GO:0030308	negative regulation of cell growth	BRCA1	IMP		Human	PMID:10518542
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BRCA1	IDA		Human	PMID:16288014
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	BRCA1	IMP		Human	PMID:23415688
Biological Process	GO:0045717	negative regulation of fatty acid biosynthetic process	BRCA1	IMP		Human	PMID:16326698
Biological Process	GO:0035067	negative regulation of histone acetylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0051572	negative regulation of histone H3-K4 methylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0051573	negative regulation of histone H3-K9 methylation	BRCA1	IDA		Human	PMID:20820192
Biological Process	GO:0051573	negative regulation of histone H3-K9 methylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	BRCA1	IMP		Human	PMID:17505062
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	BRCA1	IMP		Human	PMID:23415688
Biological Process	GO:0045766	positive regulation of angiogenesis	BRCA1	IMP		Human	PMID:23415688
Biological Process	GO:0045739	positive regulation of DNA repair	BRCA1	IMP		Human	PMID:17525340
Biological Process	GO:0045739	positive regulation of DNA repair	BRCA1	IMP		Human	PMID:17643121
Biological Process	GO:0045739	positive regulation of DNA repair	BRCA1	IMP		Human	PMID:19261748
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BRCA1	IMP		Human	PMID:12080089
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	BRCA1	IDA		Human	PMID:20160719
Biological Process	GO:0010628	positive regulation of gene expression	BRCA1	IMP		Human	PMID:23415688
Biological Process	GO:0035066	positive regulation of histone acetylation	BRCA1	IDA		Human	PMID:20820192
Biological Process	GO:0035066	positive regulation of histone acetylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	BRCA1	IDA		Human	PMID:20820192
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:2000617	positive regulation of histone H3-K9 acetylation	BRCA1	IDA		Human	PMID:20820192
Biological Process	GO:2000617	positive regulation of histone H3-K9 acetylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0051574	positive regulation of histone H3-K9 methylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:2000620	positive regulation of histone H4-K16 acetylation	BRCA1	IDA		Human	PMID:20820192
Biological Process	GO:2000620	positive regulation of histone H4-K16 acetylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0070512	positive regulation of histone H4-K20 methylation	BRCA1	IDA		Human	PMID:20820192
Biological Process	GO:0070512	positive regulation of histone H4-K20 methylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Brca1	IMP		Rat	PMID:19074549|RGD:10059411
Biological Process	GO:0031398	positive regulation of protein ubiquitination	BRCA1	IDA		Human	PMID:15965487
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BRCA1	IDA		Human	PMID:16331276
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BRCA1	IMP		Human	PMID:20820192
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	BRCA1	IMP		Human	PMID:23415688
Biological Process	GO:0006301	postreplication repair	BRCA1	IDA		Human	PMID:17349954
Biological Process	GO:0051865	protein autoubiquitination	BRCA1	IDA		Human	PMID:12890688
Biological Process	GO:0051865	protein autoubiquitination	BRCA1	IDA		Human	PMID:20351172
Biological Process	GO:0085020	protein K6-linked ubiquitination	BRCA1	IDA		Human	PMID:12890688
Biological Process	GO:0085020	protein K6-linked ubiquitination	BRCA1	IDA		Human	PMID:20351172
Biological Process	GO:0000209	protein polyubiquitination	BRCA1	IDA		Human	PMID:12485996
Biological Process	GO:0016567	protein ubiquitination	BRCA1	IDA		Human	PMID:17349954
Biological Process	GO:0051726	regulation of cell cycle	BRCA1	IDA		Human	PMID:21102443
Biological Process	GO:0044030	regulation of DNA methylation	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	Brca1	IMP		Mouse	MGI:MGI:5009779|PMID:20820192
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	BRCA1	IMP		Human	PMID:9662397
Biological Process	GO:0032355	response to estradiol	Brca1	IEP		Rat	PMID:14729590|RGD:1599501
Biological Process	GO:0043627	response to estrogen	BRCA1	IDA		Human	PMID:8895509
Biological Process	GO:0010212	response to ionizing radiation	BRCA1	IMP		Human	PMID:17525340
Biological Process	GO:0010212	response to ionizing radiation	BRCA1	IMP		Human	PMID:17643121
Biological Process	GO:0010212	response to ionizing radiation	BRCA1	IMP		Human	PMID:19261748
Biological Process	GO:0033993	response to lipid	Brca1	IEP		Rat	PMID:17342305|RGD:2293189
Biological Process	GO:0007584	response to nutrient	Brca1	IEP		Rat	PMID:17044772|RGD:1599498
Biological Process	GO:0010033	response to organic substance	Brca1	IEP		Rat	PMID:14729590|RGD:1599501

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern