Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BRD7
  • Mouse genes Brd7
  • Rat genes Brd7
  • Zfish genes brd7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Brd7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042393	histone binding	BRD7	IDA		Human	PMID:12489984
Molecular Function	GO:0070577	lysine-acetylated histone binding	BRD7	IDA		Human	PMID:16265664
Molecular Function	GO:0002039	p53 binding	BRD7	IPI	UniProtKB:P04637	Human	PMID:20228809
Molecular Function	GO:0005515	protein binding	BRD7	IPI	UniProtKB:Q9BUJ2	Human	PMID:12489984
Molecular Function	GO:0005515	protein binding	BRD7	IPI	UniProtKB:Q6QNY1	Human	PMID:18329849
Molecular Function	GO:0005515	protein binding	BRD7	IPI	UniProtKB:Q6QNY1-1	Human	PMID:18329849
Molecular Function	GO:0005515	protein binding	BRD7	IPI	UniProtKB:P04637	Human	PMID:20228809
Molecular Function	GO:0005515	protein binding	BRD7	IPI	UniProtKB:Q09472	Human	PMID:20228809
Molecular Function	GO:0005515	protein binding	BRD7	IPI	UniProtKB:P04637	Human	PMID:20660729
Molecular Function	GO:0005515	protein binding	BRD7	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Brd7	IPI	UniProtKB:Q64127	Mouse	MGI:MGI:4835371|PMID:19909775
Molecular Function	GO:0005515	protein binding	Brd7	IPI	UniProtKB:O08908|UniProtKB:P26450	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Brd7	IPI	PR:Q64512	Mouse	PMID:10526152
Molecular Function	GO:0000976	transcription cis-regulatory region binding	BRD7	IDA		Human	PMID:20228809
Molecular Function	GO:0003713	transcription coactivator activity	BRD7	IDA		Human	PMID:20228809
Molecular Function	GO:0003714	transcription corepressor activity	BRD7	IDA		Human	PMID:16265664
Molecular Function	GO:0003714	transcription corepressor activity	Brd7	IDA		Mouse	MGI:MGI:4835371|PMID:19909775
Cellular Component	GO:0005829	cytosol	BRD7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	BRD7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	BRD7	IDA		Human	PMID:11025449
Cellular Component	GO:0005634	nucleus	BRD7	IDA		Human	PMID:12489984
Cellular Component	GO:0005634	nucleus	BRD7	IDA		Human	PMID:16265664
Cellular Component	GO:0005634	nucleus	BRD7	IDA		Human	PMID:20228809
Cellular Component	GO:0005634	nucleus	BRD7	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	BRD7	IDA		Human	PMID:25593309
Cellular Component	GO:0005634	nucleus	Brd7	IPI	UniProtKB:Q9NPI1	Mouse	PMID:10526152
Cellular Component	GO:0070603	SWI/SNF superfamily-type complex	Brd7	IDA		Mouse	PMID:24335282
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BRD7	IDA		Human	PMID:16265664
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	BRD7	IDA		Human	PMID:16265664
Biological Process	GO:0007346	regulation of mitotic cell cycle	BRD7	IMP		Human	PMID:20228809
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	BRD7	IDA		Human	PMID:12489984
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	BRD7	IMP		Human	PMID:20228809

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern