Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BRD8
  • Mouse genes Brd8
  • Rat genes Brd8
  • Zfish genes brd8a,brd8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Brd8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030374	nuclear receptor coactivator activity	BRD8	IDA		Human	PMID:9368056
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	BRD8	IPI	UniProtKB:P10828	Human	PMID:9368056
Molecular Function	GO:0005515	protein binding	BRD8	IPI	UniProtKB:Q9H2F5	Human	PMID:27153538
Cellular Component	GO:0005739	mitochondrion	BRD8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	BRD8	IDA		Human	PMID:27153538
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	BRD8	IDA		Human	PMID:14966270
Cellular Component	GO:0005654	nucleoplasm	BRD8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000786	nucleosome	BRD8	IDA		Human	PMID:27153538
Cellular Component	GO:0005634	nucleus	BRD8	IDA		Human	PMID:25593309
Cellular Component	GO:0000812	Swr1 complex	BRD8	IDA		Human	PMID:24463511
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	BRD8	IDA		Human	PMID:9368056
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	brd8b	IMP		Zfish	PMID:24240475
Biological Process	GO:0043968	histone H2A acetylation	BRD8	IDA		Human	PMID:27153538
Biological Process	GO:0043967	histone H4 acetylation	BRD8	IDA		Human	PMID:27153538
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	BRD8	IDA		Human	PMID:27153538
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BRD8	IDA		Human	PMID:9368056
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Brd8	IDA		Rat	PMID:17014737|RGD:9587765
Biological Process	GO:0051726	regulation of cell cycle	BRD8	IMP		Human	PMID:27153538

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern