Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BRF1
  • Mouse genes Brf1
  • Rat genes Brf1
  • Zfish genes brf1a,brf1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Brf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	BRF1	IPI	UniProtKB:Q9H063	Human	PMID:18377933
Biological Process	GO:0021549	cerebellum development	brf1b	IMP	ZFIN:ZDB-MRPHLNO-150416-3	Zfish	PMID:25561519
Biological Process	GO:0021549	cerebellum development	brf1b	IMP	ZFIN:ZDB-CRISPR-150416-1	Zfish	PMID:25561519
Biological Process	GO:0021549	cerebellum development	brf1b	IMP	ZFIN:ZDB-MRPHLNO-150416-4	Zfish	PMID:25561519
Biological Process	GO:0030099	myeloid cell differentiation	brf1a	IMP	ZFIN:ZDB-MRPHLNO-141013-8	Zfish	PMID:25010335
Biological Process	GO:0030223	neutrophil differentiation	brf1a	IMP	ZFIN:ZDB-MRPHLNO-141013-8	Zfish	PMID:25010335
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	Brf1	IMP		Rat	PMID:18456653|RGD:9586716
Biological Process	GO:0043488	regulation of mRNA stability	Brf1	IMP		Mouse	PMID:14976220
Biological Process	GO:0002574	thrombocyte differentiation	brf1b	IMP	ZFIN:ZDB-MRPHLNO-141013-10	Zfish	PMID:25010335

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern