Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BRIP1
  • Mouse genes Brip1
  • Rat genes Brip1
  • Zfish genes brip1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Brip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043139	5'-3' DNA helicase activity	BRIP1	IDA		Human	PMID:14983014
Molecular Function	GO:0003682	chromatin binding	Brip1	IDA		Rat	PMID:22212472|RGD:11252153
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:11301010
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:14576433
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:15125843
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:15133502
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:17525340
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:17581638
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P40692	Human	PMID:17581638
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:18285836
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:19369211
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:21240188
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P54132	Human	PMID:21240188
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:22792074
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P40692	Human	PMID:22792074
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P40692	Human	PMID:23585563
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:Q96T76	Human	PMID:23585563
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P40692	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:Q9BPX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P38398	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	BRIP1	IPI	UniProtKB:P40692	Human	PMID:34591612
Cellular Component	GO:0070532	BRCA1-B complex	BRIP1	IPI		Human	PMID:16391231
Cellular Component	GO:0005737	cytoplasm	BRIP1	IDA		Human	PMID:14504288
Cellular Component	GO:0005737	cytoplasm	BRIP1	IDA		Human	PMID:23585563
Cellular Component	GO:0005737	cytoplasm	Brip1	IDA		Rat	PMID:16771696|RGD:2326085
Cellular Component	GO:0031965	nuclear membrane	BRIP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	BRIP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	BRIP1	IDA		Human	PMID:14504288
Cellular Component	GO:0005634	nucleus	BRIP1	IDA		Human	PMID:23585563
Cellular Component	GO:0005634	nucleus	Brip1	IDA		Rat	PMID:16771696|RGD:2326085
Biological Process	GO:1904385	cellular response to angiotensin	Brip1	IEP		Rat	PMID:26503970|RGD:11053113
Biological Process	GO:0071456	cellular response to hypoxia	Brip1	IEP		Rat	PMID:12511571|RGD:11251702
Biological Process	GO:0071295	cellular response to vitamin	Brip1	IEP		Rat	PMID:16771696|RGD:2326085
Biological Process	GO:0051026	chiasma assembly	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168
Biological Process	GO:1990918	double-strand break repair involved in meiotic recombination	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168
Biological Process	GO:0008584	male gonad development	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168
Biological Process	GO:0010705	meiotic DNA double-strand break processing involved in reciprocal meiotic recombination	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168
Biological Process	GO:0008285	negative regulation of cell population proliferation	Brip1	IDA		Rat	PMID:16771696|RGD:2326085
Biological Process	GO:0010629	negative regulation of gene expression	Brip1	IDA		Rat	PMID:12511571|RGD:11251702
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	BRIP1	IDA		Human	PMID:14504288
Biological Process	GO:0009636	response to toxic substance	Brip1	IEP		Rat	PMID:24243707|RGD:9831190
Biological Process	GO:0072520	seminiferous tubule development	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168
Biological Process	GO:0007286	spermatid development	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168
Biological Process	GO:0007283	spermatogenesis	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168
Biological Process	GO:0007284	spermatogonial cell division	Brip1	IMP	MGI:MGI:4129733	Mouse	PMID:26490168

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern