Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BST2
  • Mouse genes Bst2
  • Rat genes Bst2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bst2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	BST2	IPI	UniProtKB:Q10589	Human	PMID:19879838
Molecular Function	GO:0042802	identical protein binding	BST2	IPI	UniProtKB:Q10589	Human	PMID:20880831
Molecular Function	GO:0042802	identical protein binding	BST2	IPI	UniProtKB:Q10589	Human	PMID:20940320
Molecular Function	GO:0008191	metalloendopeptidase inhibitor activity	BST2	IDA		Human	PMID:22065321
Molecular Function	GO:0005515	protein binding	BST2	IPI	UniProtKB:A9QPL9	Human	PMID:19179289
Molecular Function	GO:0005515	protein binding	BST2	IPI	UniProtKB:P59901	Human	PMID:19564354
Molecular Function	GO:0005515	protein binding	BST2	IPI	UniProtKB:P50281	Human	PMID:22065321
Molecular Function	GO:0005515	protein binding	BST2	IPI	UniProtKB:P69699	Human	PMID:22072710
Molecular Function	GO:0005515	protein binding	BST2	IPI	UniProtKB:P35585	Human	PMID:24843023
Molecular Function	GO:0005515	protein binding	BST2	IPI	UniProtKB:P60033	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Bst2	IPI	UniProtKB:Q17R89	Rat	PMID:19273615|RGD:8553706
Molecular Function	GO:0042803	protein homodimerization activity	BST2	IPI	UniProtKB:Q10589	Human	PMID:20399176
Molecular Function	GO:0003723	RNA binding	BST2	HDA		Human	PMID:22658674
Cellular Component	GO:0016324	apical plasma membrane	Bst2	IDA		Rat	PMID:12956872|RGD:1302912
Cellular Component	GO:0016324	apical plasma membrane	Bst2	IDA		Rat	PMID:19273615|RGD:8553706
Cellular Component	GO:0009986	cell surface	BST2	IMP		Human	PMID:22072966
Cellular Component	GO:0009986	cell surface	Bst2	IDA		Mouse	MGI:MGI:5448513|PMID:21919738
Cellular Component	GO:0009986	cell surface	Bst2	IDA		Mouse	MGI:MGI:5437405|PMID:22284121
Cellular Component	GO:0009986	cell surface	Bst2	IDA		Rat	PMID:19273615|RGD:8553706
Cellular Component	GO:0005737	cytoplasm	BST2	IDA		Human	PMID:22065321
Cellular Component	GO:0070062	extracellular exosome	BST2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	BST2	HDA		Human	PMID:20458337
Cellular Component	GO:0005794	Golgi apparatus	BST2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	BST2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	BST2	HDA		Human	PMID:19946888
Cellular Component	GO:0005771	multivesicular body	BST2	IMP		Human	PMID:22072966
Cellular Component	GO:0005886	plasma membrane	BST2	IDA		Human	PMID:19036818
Cellular Component	GO:0005886	plasma membrane	BST2	IDA		Human	PMID:20399176
Cellular Component	GO:0005886	plasma membrane	BST2	IDA		Human	PMID:20686043
Cellular Component	GO:0005886	plasma membrane	BST2	IDA		Human	PMID:20943977
Biological Process	GO:0051607	defense response to virus	BST2	IDA		Human	PMID:20399176
Biological Process	GO:0045087	innate immune response	BST2	IDA		Human	PMID:19036818
Biological Process	GO:0045087	innate immune response	Bst2	IMP		Mouse	MGI:MGI:5448513|PMID:21919738
Biological Process	GO:0030308	negative regulation of cell growth	BST2	IDA		Human	PMID:22065321
Biological Process	GO:0030336	negative regulation of cell migration	BST2	IDA		Human	PMID:22065321
Biological Process	GO:1901253	negative regulation of intracellular transport of viral material	BST2	IDA		Human	PMID:19036818
Biological Process	GO:1901253	negative regulation of intracellular transport of viral material	BST2	IDA		Human	PMID:20686043
Biological Process	GO:1901253	negative regulation of intracellular transport of viral material	BST2	IDA		Human	PMID:20943977
Biological Process	GO:1901253	negative regulation of intracellular transport of viral material	Bst2	IMP		Mouse	MGI:MGI:5437405|PMID:22284121
Biological Process	GO:1901253	negative regulation of intracellular transport of viral material	Bst2	IDA		Mouse	MGI:MGI:5437427|PMID:20686043
Biological Process	GO:1901253	negative regulation of intracellular transport of viral material	Bst2	IMP		Mouse	MGI:MGI:5448513|PMID:21919738
Biological Process	GO:0002737	negative regulation of plasmacytoid dendritic cell cytokine production	BST2	IDA		Human	PMID:19564354
Biological Process	GO:0045071	negative regulation of viral genome replication	BST2	IDA		Human	PMID:20943977
Biological Process	GO:0045071	negative regulation of viral genome replication	Bst2	IMP		Mouse	MGI:MGI:5437405|PMID:22284121
Biological Process	GO:0045071	negative regulation of viral genome replication	Bst2	IMP		Mouse	MGI:MGI:5448513|PMID:21919738
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	BST2	HMP		Human	PMID:12761501
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Bst2	IMP		Rat	PMID:19273615|RGD:8553706
Biological Process	GO:0035455	response to interferon-alpha	Bst2	IDA		Mouse	MGI:MGI:5437405|PMID:22284121
Biological Process	GO:0035456	response to interferon-beta	Bst2	IDA		Mouse	MGI:MGI:5448513|PMID:21919738
Biological Process	GO:0034341	response to type II interferon	Bst2	IDA		Mouse	MGI:MGI:5448513|PMID:21919738
Biological Process	GO:0009615	response to virus	BST2	IDA		Human	PMID:19036818
Biological Process	GO:0009615	response to virus	BST2	IDA		Human	PMID:20686043
Biological Process	GO:0009615	response to virus	BST2	IDA		Human	PMID:20943977
Biological Process	GO:0009615	response to virus	Bst2	IDA		Mouse	MGI:MGI:5448513|PMID:21919738
Biological Process	GO:0009615	response to virus	Bst2	IDA		Mouse	MGI:MGI:5437427|PMID:20686043
Biological Process	GO:0009615	response to virus	Bst2	IDA		Mouse	MGI:MGI:5437405|PMID:22284121

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern