Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BTRC
  • Mouse genes Btrc
  • Rat genes Btrc
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Btrc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	BTRC	IDA		Human	PMID:12820959
Molecular Function	GO:0008013	beta-catenin binding	Btrc	IDA		Mouse	MGI:MGI:1336762|PMID:10228155
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P18848	Human	PMID:11238952
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:12609982
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13616	Human	PMID:12609982
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9UKT4	Human	PMID:12791267
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P35222	Human	PMID:12820959
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:12820959
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q12959	Human	PMID:12902344
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q62696	Human	PMID:12902344
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P30291	Human	PMID:15070733
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:15070733
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O95863	Human	PMID:15448698
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O15534	Human	PMID:15917222
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O70361	Human	PMID:15917222
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9C026	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P10071	Human	PMID:16371461
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P35222	Human	PMID:16376880
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13485	Human	PMID:16865698
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9HAW4	Human	PMID:16885022
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13616	Human	PMID:17318178
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q15843	Human	PMID:17318178
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q5JTC6	Human	PMID:17510365
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P35222	Human	PMID:18354482
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13127	Human	PMID:18354482
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13616	Human	PMID:18354482
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13127	Human	PMID:18354483
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q6PGQ7	Human	PMID:18521620
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q00613	Human	PMID:18794143
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P35222	Human	PMID:18805092
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:19159283
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P04637	Human	PMID:19196987
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O95863	Human	PMID:19411070
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13616	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13616	Human	PMID:19945379
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q96K76	Human	PMID:19966869
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O95863	Human	PMID:20389281
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P35222	Human	PMID:20531388
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q00987	Human	PMID:20708156
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13616	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q7L5N1	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q5D1E8	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P18848	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q5D1E8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13651	Human	PMID:22087322
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q60793	Human	PMID:22307056
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:22632967
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q02750	Human	PMID:24211253
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q5D1E8	Human	PMID:24270572
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P35222	Human	PMID:24561623
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q99952	Human	PMID:25081058
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q99952-1	Human	PMID:25081058
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O75410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P18848	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q16621	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q8WWW0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9C026	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O00444	Human	PMID:25503564
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q76N32	Human	PMID:25503564
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P10070	Human	PMID:25670079
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P35222	Human	PMID:25873176
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q7L5N1	Human	PMID:26267535
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O00444	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O75410-7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P18848	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q8WWW0-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9C026-5	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q3KP66	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P18848	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P63208	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O75410	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P18848	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q8WWW0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9C026-5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O75410-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P18848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q13651	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q5HYW2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9C026	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9NQ86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q9Y2T1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P49821	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	BTRC	IPI	UniProtKB:P25963	Human	PMID:9859996
Molecular Function	GO:0005515	protein binding	Btrc	IPI	UniProtKB:P63208	Mouse	MGI:MGI:5705222|PMID:18929646
Molecular Function	GO:0005515	protein binding	Btrc	IPI	UniProtKB:Q61985:PRO_0000443104	Mouse	MGI:MGI:5299399|PMID:21911472
Molecular Function	GO:0005515	protein binding	Btrc	IPI	UniProtKB:Q9Z301	Mouse	MGI:MGI:4844267|PMID:18782782
Molecular Function	GO:0005515	protein binding	Btrc	IPI	UniProtKB:P10071	Mouse	MGI:MGI:4943406|PMID:16371461
Molecular Function	GO:0005515	protein binding	Btrc	IPI	UniProtKB:Q60793	Mouse	MGI:MGI:6149282|PMID:29593216
Molecular Function	GO:0005515	protein binding	Btrc	IPI	PR:Q0VGT2	Mouse	PMID:16611981
Molecular Function	GO:0005515	protein binding	Btrc	IPI	PR:P42225	Mouse	PMID:18378670
Molecular Function	GO:0005515	protein binding	Btrc	IPI	PR:Q9EPK5	Mouse	PMID:17636028
Molecular Function	GO:0005515	protein binding	Btrc	IPI	PR:Q9WV60	Mouse	PMID:19047045
Molecular Function	GO:0005515	protein binding	Btrc	IPI	PR:Q04887	Mouse	PMID:19047045
Molecular Function	GO:0005515	protein binding	Btrc	IPI	PR:O70552	Mouse	PMID:32558204
Molecular Function	GO:0045309	protein phosphorylated amino acid binding	Btrc	IDA		Mouse	MGI:MGI:1336762|PMID:10228155
Molecular Function	GO:1990757	ubiquitin ligase activator activity	BTRC	IDA		Human	PMID:12820959
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	BTRC	IDA		Human	PMID:10066435
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	BTRC	IDA		Human	PMID:12820959
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Btrc	IDA		Mouse	MGI:MGI:1336762|PMID:10228155
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	BTRC	IDA		Human	PMID:15448698
Cellular Component	GO:0005737	cytoplasm	Btrc	IDA		Mouse	MGI:MGI:5705222|PMID:18929646
Cellular Component	GO:0005634	nucleus	Btrc	IDA		Mouse	MGI:MGI:5705222|PMID:18929646
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	BTRC	IDA		Human	PMID:12820959
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	BTRC	IDA		Human	PMID:19966869
Biological Process	GO:0060444	branching involved in mammary gland duct morphogenesis	Btrc	IMP	MGI:MGI:3055737	Mouse	PMID:15340078
Biological Process	GO:0071407	cellular response to organic cyclic compound	Btrc	IDA		Mouse	PMID:19103752
Biological Process	GO:0033598	mammary gland epithelial cell proliferation	Btrc	IMP	MGI:MGI:3055737	Mouse	PMID:15340078
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	BTRC	IMP		Human	PMID:19966869
Biological Process	GO:0038061	NIK/NF-kappaB signaling	BTRC	IDA		Human	PMID:10066435
Biological Process	GO:0042753	positive regulation of circadian rhythm	Btrc	IMP		Mouse	MGI:MGI:4844267|PMID:18782782
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Btrc	IMP		Mouse	MGI:MGI:4844267|PMID:18782782
Biological Process	GO:0045862	positive regulation of proteolysis	BTRC	IMP		Human	PMID:16885022
Biological Process	GO:1904668	positive regulation of ubiquitin protein ligase activity	BTRC	IDA		Human	PMID:12820959
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BTRC	IDA		Human	PMID:15917222
Biological Process	GO:0030163	protein catabolic process	Btrc	IMP	MGI:MGI:2669949	Mouse	PMID:12843402
Biological Process	GO:0006470	protein dephosphorylation	Btrc	IDA		Mouse	MGI:MGI:4844267|PMID:18782782
Biological Process	GO:0031648	protein destabilization	BTRC	IMP		Human	PMID:16885022
Biological Process	GO:0070936	protein K48-linked ubiquitination	Btrc	IDA		Mouse	PMID:29593216
Biological Process	GO:0000209	protein polyubiquitination	BTRC	IDA		Human	PMID:12820959
Biological Process	GO:0000209	protein polyubiquitination	BTRC	IMP		Human	PMID:12820959
Biological Process	GO:0000209	protein polyubiquitination	Btrc	IDA		Mouse	MGI:MGI:1336762|PMID:10228155
Biological Process	GO:0016567	protein ubiquitination	BTRC	IDA		Human	PMID:16885022
Biological Process	GO:0016567	protein ubiquitination	BTRC	IDA		Human	PMID:18354482
Biological Process	GO:0016567	protein ubiquitination	BTRC	IMP		Human	PMID:21258371
Biological Process	GO:0016567	protein ubiquitination	Btrc	IDA		Mouse	PMID:32558204
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	Btrc	IDA		Mouse	MGI:MGI:5705222|PMID:18929646
Biological Process	GO:0051726	regulation of cell cycle	Btrc	IMP	MGI:MGI:3055737	Mouse	PMID:12791266
Biological Process	GO:0042752	regulation of circadian rhythm	BTRC	IDA		Human	PMID:15917222
Biological Process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	Btrc	IMP	MGI:MGI:2669949	Mouse	PMID:12843402
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	Btrc	IDA		Mouse	PMID:19103752
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Btrc	IDA		Mouse	MGI:MGI:5299399|PMID:21911472
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Btrc	IDA		Mouse	PMID:32558204
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	BTRC	IDA		Human	PMID:15448698

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern