Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C1R
  • Mouse genes C1rb
  • Rat genes C1r
  • Zfish genes c1r
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set C1rb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	C1R	IDA		Human	PMID:20178990
Molecular Function	GO:0042802	identical protein binding	C1R	IPI	UniProtKB:P00736	Human	PMID:20970424
Molecular Function	GO:0042802	identical protein binding	C1R	IPI	UniProtKB:P00736	Human	PMID:31749804
Molecular Function	GO:0140313	molecular sequestering activity	C1R	EXP		Human	PMID:20178990
Molecular Function	GO:0005515	protein binding	C1R	IPI	UniProtKB:P09871	Human	PMID:12788922
Molecular Function	GO:0005515	protein binding	C1R	IPI	UniProtKB:P09871	Human	PMID:17996945
Molecular Function	GO:0005515	protein binding	C1R	IPI	UniProtKB:P09871	Human	PMID:2387866
Molecular Function	GO:0005515	protein binding	C1R	IPI	UniProtKB:P09871	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	C1R	IPI	UniProtKB:P05155	Human	PMID:28742139
Molecular Function	GO:0005515	protein binding	C1R	IPI	UniProtKB:P09871	Human	PMID:31749804
Molecular Function	GO:0004252	serine-type endopeptidase activity	C1R	EXP		Human	PMID:11823416
Cellular Component	GO:0072562	blood microparticle	C1R	HDA		Human	PMID:22516433
Cellular Component	GO:0070062	extracellular exosome	C1R	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	C1R	IDA		Human	PMID:20178990
Biological Process	GO:0031638	zymogen activation	C1R	IDA		Human	PMID:20178990

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern