Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C6
  • Mouse genes C6
  • Rat genes C6
  • Zfish genes c6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set C6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	C6	IPI	UniProtKB:P16333	Human	PMID:17474147
Cellular Component	GO:0070062	extracellular exosome	C6	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	C6	IDA		Rat	PMID:8089494|RGD:1600681
Cellular Component	GO:0005579	membrane attack complex	C6	IPI		Human	PMID:30552328
Cellular Component	GO:0005579	membrane attack complex	C6	IDA		Human	PMID:22832194
Biological Process	GO:0006956	complement activation	C6	IDA		Human	PMID:2808363
Biological Process	GO:0042742	defense response to bacterium	c6	IDA		Zfish	PMID:29572872
Biological Process	GO:0006955	immune response	c6	IDA		Zfish	PMID:29572872
Biological Process	GO:0001701	in utero embryonic development	C6	IGI	MGI:MGI:88513	Mouse	PMID:18947875
Biological Process	GO:0001970	positive regulation of activation of membrane attack complex	C6	IMP		Mouse	MGI:MGI:4430818|PMID:15611275
Biological Process	GO:0045766	positive regulation of angiogenesis	C6	IMP		Mouse	MGI:MGI:4430818|PMID:15611275
Biological Process	GO:0043065	positive regulation of apoptotic process	C6	IMP		Rat	PMID:10807586|RGD:1600489
Biological Process	GO:0045917	positive regulation of complement activation	C6	IMP		Mouse	MGI:MGI:4430818|PMID:15611275

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern