Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CACNA1G
  • Mouse genes Cacna1g
  • Rat genes Cacna1g
  • Zfish genes cacna1g
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacna1g

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	CACNA1G	IDA		Human	PMID:21084288
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	CACNA1G	IDA		Human	PMID:26456284
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	CACNA1G	IDA		Human	PMID:26715324
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	Cacna1g	IDA		Mouse	PMID:16690884
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	Cacna1g	IDA		Rat	PMID:16935432|RGD:7207257
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	Cacna1g	IDA		Rat	PMID:18759855|RGD:2308879
Molecular Function	GO:0008332	low voltage-gated calcium channel activity	Cacna1g	IDA		Rat	PMID:18760992|RGD:7175320
Molecular Function	GO:0005515	protein binding	Cacna1g	IPI	PR:P51637	Mouse	PMID:21084288
Molecular Function	GO:0097110	scaffold protein binding	CACNA1G	IPI	UniProtKB:P56539	Human	PMID:21084288
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacna1g	IDA		Mouse	PMID:11230107
Molecular Function	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Molecular Function	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Cellular Component	GO:0044297	cell body	Cacna1g	IDA		Rat	PMID:10400082|RGD:7175537
Cellular Component	GO:0005737	cytoplasm	CACNA1G	IDA		Human	PMID:26715324
Cellular Component	GO:0030425	dendrite	Cacna1g	IDA		Rat	PMID:17100846|RGD:2308880
Cellular Component	GO:0016020	membrane	Cacna1g	IDA		Rat	PMID:18759855|RGD:2308879
Cellular Component	GO:0043025	neuronal cell body	Cacna1g	IDA		Rat	PMID:17100846|RGD:2308880
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Cacna1g	IDA		Rat	PMID:18759855|RGD:2308879
Cellular Component	GO:0005886	plasma membrane	CACNA1G	IDA		Human	PMID:26715324
Cellular Component	GO:0005886	plasma membrane	Cacna1g	IDA		Mouse	PMID:11230107
Cellular Component	GO:0005886	plasma membrane	Cacna1g	IDA		Mouse	PMID:16690884
Cellular Component	GO:0005886	plasma membrane	Cacna1g	IDA		Rat	PMID:12555202|RGD:727502
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacna1g	IDA		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0001508	action potential	Cacna1g	IMP	MGI:MGI:3530501	Mouse	PMID:17761775
Biological Process	GO:0014824	artery smooth muscle contraction	Cacna1g	IMP		Rat	PMID:18759855|RGD:2308879
Biological Process	GO:0086016	AV node cell action potential	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0086027	AV node cell to bundle of His cell signaling	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0070509	calcium ion import	CACNA1G	IDA		Human	PMID:21084288
Biological Process	GO:0070509	calcium ion import	Cacna1g	IDA		Rat	PMID:16935432|RGD:7207257
Biological Process	GO:0070588	calcium ion transmembrane transport	CACNA1G	IDA		Human	PMID:26456284
Biological Process	GO:0070588	calcium ion transmembrane transport	CACNA1G	IDA		Human	PMID:26715324
Biological Process	GO:0070588	calcium ion transmembrane transport	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0060402	calcium ion transport into cytosol	Cacna1g	IDA		Rat	PMID:18760992|RGD:7175320
Biological Process	GO:0086002	cardiac muscle cell action potential involved in contraction	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Cacna1g	IEP		Rat	PMID:18820838|RGD:2316203
Biological Process	GO:0007268	chemical synaptic transmission	Cacna1g	IGI	MGI:MGI:95808	Mouse	PMID:19657020
Biological Process	GO:0086045	membrane depolarization during AV node cell action potential	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0086046	membrane depolarization during SA node cell action potential	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Cacna1g	IMP		Rat	PMID:17172292|RGD:2316206
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Cacna1g	IMP		Rat	PMID:11577029|RGD:2308878
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Cacna1g	IMP		Rat	PMID:18759855|RGD:2308879
Biological Process	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization	Cacna1g	IMP	MGI:MGI:2182962	Mouse	PMID:16690884
Biological Process	GO:0051924	regulation of calcium ion transport	Cacna1g	IMP		Rat	PMID:17172292|RGD:2316206
Biological Process	GO:0002027	regulation of heart rate	Cacna1g	IMP	MGI:MGI:2182962	Mouse	PMID:16690884
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0042391	regulation of membrane potential	CACNA1G	IDA		Human	PMID:21084288
Biological Process	GO:0010045	response to nickel cation	Cacna1g	IMP	MGI:MGI:2182962	Mouse	PMID:16690884
Biological Process	GO:0086015	SA node cell action potential	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884
Biological Process	GO:0086018	SA node cell to atrial cardiac muscle cell signaling	Cacna1g	IMP		Mouse	MGI:MGI:3714901|PMID:16690884

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern