Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cacnb3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CACNB3
- Mouse genes Cacnb3
- Rat genes Cacnb3
- Zfish genes cacnb3a,cacnb3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacnb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005246	calcium channel regulator activity	Cacnb3	IMP		Rat	PMID:10666413\|RGD:13673808
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	Cacnb3	IDA		Rat	PMID:25527503\|RGD:11059598
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:Q13936	Human	PMID:18535142
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:P50221	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:P55040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:Q15477	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:Q6FI81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:Q8TAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CACNB3	IPI	UniProtKB:Q9H1P6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cacnb3	IPI	PR:O55017	Mouse	PMID:10328888
Molecular Function	GO:0005515	protein binding	Cacnb3	IPI	PR:P97445	Mouse	PMID:10328888
Molecular Function	GO:0005515	protein binding	Cacnb3	IPI	UniProtKB:P22002	Rat	PMID:15170217\|RGD:11558004
Molecular Function	GO:0005515	protein binding	Cacnb3	IPI	UniProtKB:Q05152	Rat	PMID:16049174\|RGD:8553837
Molecular Function	GO:0005515	protein binding	Cacnb3	IPI	UniProtKB:P55040	Rat	PMID:20679232\|RGD:13432322
Molecular Function	GO:0005515	protein binding	Cacnb3	IPI	UniProtKB:Q66L44	Rat	PMID:24751537\|RGD:10047103
Molecular Function	GO:0019901	protein kinase binding	Cacnb3	IDA		Rat	PMID:18205403\|RGD:7175532
Molecular Function	GO:0005245	voltage-gated calcium channel activity	CACNB3	IDA		Human	PMID:11160515
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Cacnb3	IMP		Rat	PMID:14559910\|RGD:1358466
Cellular Component	GO:0016324	apical plasma membrane	Cacnb3	IDA		Rat	PMID:17272350\|RGD:2308883
Cellular Component	GO:1990454	L-type voltage-gated calcium channel complex	Cacnb3	IMP		Rat	PMID:10666413\|RGD:13673808
Cellular Component	GO:1990454	L-type voltage-gated calcium channel complex	Cacnb3	IDA		Rat	PMID:15170217\|RGD:11558004
Cellular Component	GO:1990454	L-type voltage-gated calcium channel complex	Cacnb3	IDA		Rat	PMID:25527503\|RGD:11059598
Cellular Component	GO:0016020	membrane	CACNB3	IDA		Human	PMID:16525042
Cellular Component	GO:0005891	voltage-gated calcium channel complex	CACNB3	IDA		Human	PMID:11160515
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacnb3	IDA		Mouse	PMID:10328888
Cellular Component	GO:0005891	voltage-gated calcium channel complex	Cacnb3	IDA		Rat	PMID:7685340\|RGD:634680
Biological Process	GO:0070588	calcium ion transmembrane transport	Cacnb3	IDA		Rat	PMID:25527503\|RGD:11059598
Biological Process	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	Cacnb3	IDA		Rat	PMID:15170217\|RGD:11558004
Biological Process	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	Cacnb3	IDA		Rat	PMID:25527503\|RGD:11059598
Biological Process	GO:0006816	calcium ion transport	CACNB3	IDA		Human	PMID:11160515
Biological Process	GO:0060402	calcium ion transport into cytosol	Cacnb3	IDA		Rat	PMID:25527503\|RGD:11059598
Biological Process	GO:0090650	cellular response to oxygen-glucose deprivation	Cacnb3	IEP		Rat	PMID:23421680\|RGD:13514095
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	Cacnb3	IMP		Rat	PMID:22187436\|RGD:13514092
Biological Process	GO:1905788	negative regulation of detection of mechanical stimulus involved in sensory perception of touch	Cacnb3	IMP		Rat	PMID:22187436\|RGD:13514092
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	Cacnb3	IDA		Rat	PMID:15024042\|RGD:13514097
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Cacnb3	IMP		Rat	PMID:22187436\|RGD:13514092
Biological Process	GO:1901843	positive regulation of high voltage-gated calcium channel activity	Cacnb3	IMP		Rat	PMID:10666413\|RGD:13673808
Biological Process	GO:1901843	positive regulation of high voltage-gated calcium channel activity	Cacnb3	IMP		Rat	PMID:22187436\|RGD:13514092
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Cacnb3	IMP		Rat	PMID:20478999\|RGD:13514093
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	Cacnb3	IDA		Rat	PMID:15024042\|RGD:13514097
Biological Process	GO:0072659	protein localization to plasma membrane	Cacnb3	IDA		Rat	PMID:25527503\|RGD:11059598
Biological Process	GO:1902630	regulation of membrane hyperpolarization	Cacnb3	IDA		Rat	PMID:15024042\|RGD:13514097
Biological Process	GO:0098903	regulation of membrane repolarization during action potential	Cacnb3	IDA		Rat	PMID:25527503\|RGD:11059598
Biological Process	GO:0050852	T cell receptor signaling pathway	Cacnb3	IMP	MGI:MGI:2389248	Mouse	PMID:17028169

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.