Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CACNG8
  • Mouse genes Cacng8
  • Rat genes Cacng8
  • Zfish genes cacng8a,cacng8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacng8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005246	calcium channel regulator activity	Cacng8	IDA		Mouse	MGI:MGI:6164122|PMID:21127204
Molecular Function	GO:0005246	calcium channel regulator activity	Cacng8	IDA		Mouse	PMID:29490264
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Cacng8	IDA		Rat	PMID:12771129|RGD:13515082
Molecular Function	GO:0005515	protein binding	Cacng8	IPI	RGD:61862	Rat	PMID:24418105|RGD:8553314
Molecular Function	GO:0005515	protein binding	Cacng8	IPI	RGD:621531	Rat	PMID:24418105|RGD:8553314
Molecular Function	GO:0005515	protein binding	Cacng8	IPI	UniProtKB:P63329	Rat	PMID:24418105|RGD:8553314
Molecular Function	GO:0005515	protein binding	Cacng8	IPI	UniProtKB:Q08209	Rat	PMID:24418105|RGD:8553314
Molecular Function	GO:0030346	protein phosphatase 2B binding	Cacng8	IPI	RGD:3382	Rat	PMID:24418105|RGD:8553314
Molecular Function	GO:0030346	protein phosphatase 2B binding	Cacng8	IPI	RGD:3383	Rat	PMID:24418105|RGD:8553314
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Cacng8	IDA		Rat	PMID:19265014|RGD:8554136
Cellular Component	GO:0032590	dendrite membrane	Cacng8	IDA		Rat	PMID:24418105|RGD:8553314
Cellular Component	GO:0098978	glutamatergic synapse	Cacng8	IMP		Mouse	PMID:17074043
Cellular Component	GO:0098978	glutamatergic synapse	Cacng8	IDA		Mouse	PMID:17074043
Cellular Component	GO:0098978	glutamatergic synapse	Cacng8	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:1990454	L-type voltage-gated calcium channel complex	Cacng8	IDA		Mouse	MGI:MGI:6164122|PMID:21127204
Cellular Component	GO:0014069	postsynaptic density	Cacng8	IDA		Mouse	MGI:MGI:4879039|PMID:21172611
Cellular Component	GO:0014069	postsynaptic density	Cacng8	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng8	IDA		Mouse	PMID:27076426
Cellular Component	GO:0098839	postsynaptic density membrane	Cacng8	IDA		Rat	PMID:12771129|RGD:13515082
Cellular Component	GO:0045211	postsynaptic membrane	Cacng8	IDA		Rat	PMID:24418105|RGD:8553314
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cacng8	IDA		Mouse	PMID:27076426
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cacng8	IMP		Mouse	PMID:17074043
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cacng8	IDA		Mouse	PMID:17074043
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	Cacng8	IDA		Rat	PMID:12771129|RGD:13515082
Biological Process	GO:2000311	regulation of AMPA receptor activity	CACNG8	IDA		Human	PMID:20805473
Biological Process	GO:2000311	regulation of AMPA receptor activity	CACNG8	IDA		Human	PMID:21172611
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng8	IDA		Mouse	MGI:MGI:4879039|PMID:21172611
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng8	IDA		Mouse	PMID:29490264
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng8	IDA		Rat	PMID:17880894|RGD:8553817
Biological Process	GO:2000311	regulation of AMPA receptor activity	Cacng8	IDA		Rat	PMID:19234459|RGD:8554069
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Cacng8	IMP		Mouse	PMID:17074043
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Cacng8	IDA		Mouse	PMID:17074043

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern