Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CACYBP
  • Mouse genes Cacybp
  • Rat genes Cacybp
  • Zfish genes cacybp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cacybp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0060090	molecular adaptor activity	Cacybp	EXP		Mouse	MGI:MGI:5882894|PMID:15996101
Molecular Function	GO:0005515	protein binding	CACYBP	IPI	UniProtKB:Q8IUQ4	Human	PMID:16085652
Molecular Function	GO:0005515	protein binding	CACYBP	IPI	UniProtKB:P04626	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	CACYBP	IPI	UniProtKB:P06703	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	CACYBP	IPI	UniProtKB:P26447	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	CACYBP	IPI	UniProtKB:P33763	Human	PMID:31837246
Molecular Function	GO:0005515	protein binding	CACYBP	IPI	UniProtKB:P04626	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Cacybp	IPI	UniProtKB:Q9QWV4	Mouse	MGI:MGI:2388865|PMID:12176995
Molecular Function	GO:0005515	protein binding	Cacybp	IPI	UniProtKB:P02638|UniProtKB:P02639|UniProtKB:P14069|UniProtKB:P25815	Mouse	MGI:MGI:5486571|PMID:12042313
Molecular Function	GO:0005515	protein binding	Cacybp	IPI	PR:P14069	Mouse	PMID:9572262
Molecular Function	GO:0019904	protein domain specific binding	Cacybp	IPI	UniProtKB:P63208	Mouse	MGI:MGI:5882894|PMID:15996101
Molecular Function	GO:0042803	protein homodimerization activity	CACYBP	IPI	UniProtKB:Q9HB71	Human	PMID:16085652
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Cacybp	IPI	UniProtKB:P61092	Mouse	MGI:MGI:5882894|PMID:15996101
Cellular Component	GO:0030877	beta-catenin destruction complex	CACYBP	IDA		Human	PMID:16085652
Cellular Component	GO:0044297	cell body	Cacybp	IDA		Rat	PMID:18506390|RGD:2326112
Cellular Component	GO:0005737	cytoplasm	Cacybp	IDA		Mouse	PMID:11927578
Cellular Component	GO:0005737	cytoplasm	Cacybp	IDA		Rat	PMID:18506390|RGD:2326112
Cellular Component	GO:0005829	cytosol	CACYBP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	CACYBP	HDA		Human	PMID:20458337
Cellular Component	GO:0043005	neuron projection	Cacybp	IDA		Rat	PMID:18506390|RGD:2326112
Cellular Component	GO:0005641	nuclear envelope lumen	Cacybp	IDA		Mouse	PMID:11927578
Cellular Component	GO:0005654	nucleoplasm	CACYBP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Cacybp	IDA		Rat	PMID:18506390|RGD:2326112
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	Cacybp	IMP		Mouse	MGI:MGI:5882894|PMID:15996101
Biological Process	GO:0007568	aging	Cacybp	IEP		Rat	PMID:18506390|RGD:2326112
Biological Process	GO:0055007	cardiac muscle cell differentiation	Cacybp	IDA		Rat	PMID:16440310|RGD:2326117
Biological Process	GO:0071277	cellular response to calcium ion	Cacybp	IEP		Rat	PMID:11927578|RGD:625428
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Cacybp	IEP		Mouse	PMID:20439489
Biological Process	GO:0007507	heart development	Cacybp	IEP		Rat	PMID:16440310|RGD:2326117
Biological Process	GO:0045740	positive regulation of DNA replication	Cacybp	IDA		Rat	PMID:16440310|RGD:2326117
Biological Process	GO:0060416	response to growth hormone	Cacybp	IMP		Rat	PMID:18985281|RGD:2315627

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern