Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CADM1
  • Mouse genes Cadm1
  • Rat genes Cadm1
  • Zfish genes cadm1a,cadm1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cadm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	Cadm1	IPI	RGD:1313848	Rat	PMID:18003830|RGD:2289094
Molecular Function	GO:0050839	cell adhesion molecule binding	Cadm1	IPI	RGD:1322221	Rat	PMID:18003830|RGD:2289094
Molecular Function	GO:0030165	PDZ domain binding	Cadm1	IPI	UniProtKB:Q9JLB0	Mouse	MGI:MGI:2675176|PMID:12826663
Molecular Function	GO:0005515	protein binding	CADM1	IPI	UniProtKB:Q9Y2J2	Human	PMID:12234973
Molecular Function	GO:0005515	protein binding	CADM1	IPI	UniProtKB:O35696	Human	PMID:20479255
Molecular Function	GO:0005515	protein binding	CADM1	IPI	UniProtKB:Q64690	Human	PMID:20479255
Molecular Function	GO:0005515	protein binding	CADM1	IPI	UniProtKB:O95727-1	Human	PMID:23871486
Molecular Function	GO:0005515	protein binding	CADM1	IPI	UniProtKB:Q13368	Human	PMID:24503895
Molecular Function	GO:0005515	protein binding	CADM1	IPI	UniProtKB:P60900	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CADM1	IPI	UniProtKB:Q13368	Human	PMID:29099056
Molecular Function	GO:0005515	protein binding	Cadm1	IPI	UniProtKB:P16144	Mouse	MGI:MGI:5317999|PMID:21880726
Molecular Function	GO:0005515	protein binding	Cadm1	IPI	UniProtKB:Q8BLQ9	Mouse	MGI:MGI:2675176|PMID:12826663
Molecular Function	GO:0005515	protein binding	Cadm1	IPI	PR:Q99NH2	Mouse	PMID:18055550
Molecular Function	GO:0005515	protein binding	Cadm1	IPI	PR:O70589	Mouse	PMID:12202822
Molecular Function	GO:0005515	protein binding	Cadm1	IPI	PR:Q9D8B7	Mouse	PMID:18055550
Molecular Function	GO:0005515	protein binding	Cadm1	IPI	UniProtKB:D3ZAA9	Rat	PMID:27756895|RGD:12790644
Molecular Function	GO:0042803	protein homodimerization activity	Cadm1	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Molecular Function	GO:0005102	signaling receptor binding	CADM1	IPI	UniProtKB:O95727	Human	PMID:15811952
Molecular Function	GO:0005102	signaling receptor binding	Cadm1	IPI	UniProtKB:Q149L7	Mouse	MGI:MGI:3689781|PMID:15811952
Cellular Component	GO:0030424	axon	Cadm1	IDA		Mouse	PMID:15707673
Cellular Component	GO:0016323	basolateral plasma membrane	Cadm1	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Cellular Component	GO:0005911	cell-cell junction	Cadm1	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Cellular Component	GO:0005911	cell-cell junction	Cadm1	IDA		Mouse	PMID:22512338
Cellular Component	GO:0030425	dendrite	Cadm1	IDA		Mouse	PMID:15707673
Cellular Component	GO:0030425	dendrite	Cadm1	IDA		Rat	PMID:23769722|RGD:152975632
Cellular Component	GO:0098978	glutamatergic synapse	Cadm1	IDA		Mouse	PMID:12202822
Cellular Component	GO:0098978	glutamatergic synapse	Cadm1	IMP		Mouse	PMID:12202822
Cellular Component	GO:0043005	neuron projection	Cadm1	IDA		Rat	PMID:18003830|RGD:2289094
Cellular Component	GO:0005886	plasma membrane	CADM1	IDA		Human	PMID:15811952
Cellular Component	GO:0005886	plasma membrane	Cadm1	IDA		Mouse	MGI:MGI:5581366|PMID:24687959
Cellular Component	GO:0005886	plasma membrane	Cadm1	IDA		Mouse	PMID:15707673
Cellular Component	GO:0005886	plasma membrane	Cadm1	IDA		Rat	PMID:18003830|RGD:2289094
Cellular Component	GO:0014069	postsynaptic density	Cadm1	IDA		Rat	PMID:27756895|RGD:12790644
Cellular Component	GO:0045211	postsynaptic membrane	Cadm1	IDA		Mouse	PMID:26687224
Cellular Component	GO:0042734	presynaptic membrane	Cadm1	IDA		Mouse	PMID:26687224
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cadm1	IDA		Mouse	PMID:21145003
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cadm1	IMP		Mouse	PMID:21145003
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cadm1	IDA		Mouse	PMID:26687224
Cellular Component	GO:0045202	synapse	Cadm1	IDA		Mouse	PMID:12202822
Cellular Component	GO:0008021	synaptic vesicle	Cadm1	IDA		Mouse	PMID:12202822
Biological Process	GO:0060348	bone development	Cadm1	IMP		Mouse	PMID:22876197
Biological Process	GO:0007420	brain development	Cadm1	IEP		Rat	PMID:18003830|RGD:2289094
Biological Process	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	Cadm1	IDA		Mouse	PMID:12202822
Biological Process	GO:0007155	cell adhesion	Cadm1	IDA		Mouse	PMID:12202822
Biological Process	GO:0008037	cell recognition	CADM1	IDA		Human	PMID:15811952
Biological Process	GO:0008037	cell recognition	Cadm1	IDA		Mouse	MGI:MGI:3689781|PMID:15811952
Biological Process	GO:0051606	detection of stimulus	CADM1	IDA		Human	PMID:15811952
Biological Process	GO:0051606	detection of stimulus	Cadm1	IDA		Mouse	MGI:MGI:3689781|PMID:15811952
Biological Process	GO:0021782	glial cell development	cadm1b	IMP	ZFIN:ZDB-CRISPR-191008-20,ZFIN:ZDB-CRISPR-191008-21	Zfish	PMID:30924555
Biological Process	GO:0021782	glial cell development	cadm1a	IMP	ZFIN:ZDB-CRISPR-191009-80,ZFIN:ZDB-CRISPR-191009-81	Zfish	PMID:30924555
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Cadm1	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Cadm1	IMP		Mouse	MGI:MGI:5581366|PMID:24687959
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	Cadm1	IDA		Mouse	MGI:MGI:2675176|PMID:12826663
Biological Process	GO:0001889	liver development	Cadm1	IMP		Rat	PMID:17326163|RGD:2289097
Biological Process	GO:0097021	lymphocyte migration into lymphoid organs	Cadm1	IMP		Mouse	MGI:MGI:5581366|PMID:24687959
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Cadm1	IDA		Mouse	PMID:21145003
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Cadm1	IMP		Mouse	PMID:21145003
Biological Process	GO:0120154	negative regulation of ERBB4 signaling pathway	Cadm1	IMP		Rat	PMID:23769722|RGD:152975632
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Cadm1	IMP		Rat	PMID:23769722|RGD:152975632
Biological Process	GO:0001819	positive regulation of cytokine production	CADM1	IDA		Human	PMID:15811952
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	CADM1	IDA		Human	PMID:15811952
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	Cadm1	IDA		Mouse	MGI:MGI:3689781|PMID:15811952
Biological Process	GO:0099054	presynapse assembly	Cadm1	IDA		Mouse	PMID:12202822
Biological Process	GO:0099054	presynapse assembly	Cadm1	IMP		Mouse	PMID:12202822
Biological Process	GO:0060041	retina development in camera-type eye	cadm1b	IMP	ZFIN:ZDB-CRISPR-191008-20,ZFIN:ZDB-CRISPR-191008-21	Zfish	PMID:30924555
Biological Process	GO:0060041	retina development in camera-type eye	cadm1a	IMP	ZFIN:ZDB-CRISPR-191009-80,ZFIN:ZDB-CRISPR-191009-81	Zfish	PMID:30924555
Biological Process	GO:0098942	retrograde trans-synaptic signaling by trans-synaptic protein complex	Cadm1	IMP		Mouse	PMID:23209303
Biological Process	GO:0098942	retrograde trans-synaptic signaling by trans-synaptic protein complex	Cadm1	IDA		Mouse	PMID:23209303
Biological Process	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	CADM1	IDA		Human	PMID:15811952
Biological Process	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	Cadm1	IDA		Mouse	MGI:MGI:3689781|PMID:15811952
Biological Process	GO:0007416	synapse assembly	Cadm1	IDA		Mouse	PMID:12202822
Biological Process	GO:0007416	synapse assembly	Cadm1	IDA		Mouse	PMID:21145003
Biological Process	GO:0007416	synapse assembly	Cadm1	IMP		Mouse	PMID:21145003
Biological Process	GO:0099560	synaptic membrane adhesion	Cadm1	IPI		Mouse	PMID:18003830
Biological Process	GO:0099560	synaptic membrane adhesion	Cadm1	IDA		Mouse	PMID:18003830
Biological Process	GO:0099560	synaptic membrane adhesion	Cadm1	IEP		Mouse	PMID:18003830
Biological Process	GO:0009826	unidimensional cell growth	Cadm1	IMP	MGI:MGI:3769418	Mouse	PMID:18055550

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern