Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CADPS
  • Mouse genes Cadps
  • Rat genes Cadps
  • Zfish genes cadpsa,cadpsb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cadps

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Cadps	IDA		Rat	PMID:9289490|RGD:1299539
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Cadps	IDA		Rat	PMID:9525942|RGD:10047153
Molecular Function	GO:0005515	protein binding	CADPS	IPI	UniProtKB:Q5SSG5	Human	PMID:17984325
Molecular Function	GO:0005515	protein binding	Cadps	IPI	PR:P11531	Mouse	PMID:12659812
Molecular Function	GO:0005515	protein binding	Cadps	IPI	UniProtKB:P32851	Rat	PMID:19805029|RGD:13432245
Molecular Function	GO:0019901	protein kinase binding	Cadps	IPI	UniProtKB:Q5S007	Mouse	MGI:MGI:4941068|PMID:21307259
Cellular Component	GO:0031410	cytoplasmic vesicle	Cadps	IDA		Mouse	PMID:15820695
Cellular Component	GO:0031045	dense core granule	Cadps	IDA		Rat	PMID:24356451|RGD:11535098
Cellular Component	GO:0098674	extrinsic component of neuronal dense core vesicle membrane	Cadps	IDA		Rat	PMID:9697858|RGD:13702263
Cellular Component	GO:0098978	glutamatergic synapse	Cadps	IDA		Mouse	PMID:18022372
Cellular Component	GO:0098978	glutamatergic synapse	Cadps	IMP		Mouse	PMID:18022372
Cellular Component	GO:0098978	glutamatergic synapse	Cadps	IDA		Rat	PMID:14530279|RGD:13702394
Cellular Component	GO:0098793	presynapse	Cadps	IDA		Rat	PMID:14530279|RGD:13702394
Biological Process	GO:0050432	catecholamine secretion	Cadps	IMP	MGI:MGI:3583931	Mouse	PMID:15820695
Biological Process	GO:0051649	establishment of localization in cell	Cadps	IMP	MGI:MGI:3583931	Mouse	PMID:15820695
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Cadps	IMP		Rat	PMID:9289490|RGD:1299539
Biological Process	GO:0045921	positive regulation of exocytosis	Cadps	IMP		Rat	PMID:24356451|RGD:11535098
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	Cadps	IGI	UniProtKB:Q8BYR5	Mouse	MGI:MGI:5634021|PMID:25719439
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	Cadps	IDA		Mouse	PMID:25719439
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	Cadps	IMP		Mouse	PMID:25719439
Biological Process	GO:0016082	synaptic vesicle priming	Cadps	IGI	UniProtKB:Q8BYR5	Mouse	MGI:MGI:5617001|PMID:25374362
Biological Process	GO:0016082	synaptic vesicle priming	Cadps	IGI	MGI:MGI:2443963	Mouse	PMID:21040848
Biological Process	GO:0016082	synaptic vesicle priming	Cadps	IMP		Mouse	PMID:18022372
Biological Process	GO:0016082	synaptic vesicle priming	Cadps	IDA		Mouse	PMID:18022372
Biological Process	GO:0016050	vesicle organization	Cadps	IMP	MGI:MGI:3583931	Mouse	PMID:15820695

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern