Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Calcr

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CALCR
- Mouse genes Calcr
- Rat genes Calcr
- Zfish genes calcr
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Calcr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097643	amylin receptor activity	CALCR	IGI	UniProtKB:O60894,UniProtKB:P06881\|UniProtKB:O60894,UniProtKB:P10997:PRO_0000004106\|UniProtKB:O60894,UniProtKB:P12969:PRO_0000004122\|UniProtKB:O60894,UniProtKB:P35318\|UniProtKB:O60895,UniProtKB:P12969:PRO_0000004122\|UniProtKB:O60895,UniProtKB:P35318\|UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Molecular Function	GO:0097643	amylin receptor activity	CALCR	IPI	UniProtKB:O60894	Human	PMID:14722252
Molecular Function	GO:0032841	calcitonin binding	CALCR	IPI	UniProtKB:P01263	Human	PMID:15563840
Molecular Function	GO:0032841	calcitonin binding	CALCR	IDA		Human	PMID:8078488
Molecular Function	GO:0032841	calcitonin binding	Calcr	IDA		Rat	PMID:7723741\|RGD:2303052
Molecular Function	GO:0001635	calcitonin gene-related peptide receptor activity	CALCR	IPI	UniProtKB:O60894	Human	PMID:14722252
Molecular Function	GO:0004948	calcitonin receptor activity	Calcr	IDA		Mouse	PMID:7988453
Molecular Function	GO:0004948	calcitonin receptor activity	Calcr	IDA		Rat	PMID:7723741\|RGD:2303052
Molecular Function	GO:0004948	calcitonin receptor activity	Calcr	IDA		Rat	PMID:8395656\|RGD:727711
Molecular Function	GO:0005515	protein binding	CALCR	IPI	UniProtKB:P06881	Human	PMID:14722252
Molecular Function	GO:0005515	protein binding	CALCR	IPI	UniProtKB:Q91157	Human	PMID:7588285
Cellular Component	GO:0001669	acrosomal vesicle	Calcr	IDA		Mouse	PMID:12704735
Cellular Component	GO:0150056	amylin receptor complex 1	CALCR	IDA		Human	PMID:22500019
Cellular Component	GO:0150057	amylin receptor complex 2	CALCR	IDA		Human	PMID:22500019
Cellular Component	GO:0150058	amylin receptor complex 3	CALCR	IDA		Human	PMID:22500019
Cellular Component	GO:0030424	axon	Calcr	IDA		Rat	PMID:15571671\|RGD:1598634
Cellular Component	GO:0005929	cilium	Calcr	IDA		Mouse	PMID:12704735
Cellular Component	GO:0043005	neuron projection	Calcr	IDA		Rat	PMID:15571671\|RGD:1598634
Cellular Component	GO:0043025	neuronal cell body	Calcr	IDA		Rat	PMID:15571671\|RGD:1598634
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IDA		Human	PMID:14722252
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IDA		Human	PMID:15563840
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	ComplexPortal:CPX-1134,UniProtKB:O60896	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	UniProtKB:O60894,UniProtKB:P06881	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	UniProtKB:O60894,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	UniProtKB:O60894,UniProtKB:P12969:PRO_0000004122	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	UniProtKB:O60894,UniProtKB:P35318	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	UniProtKB:O60895,UniProtKB:P12969:PRO_0000004122	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	UniProtKB:O60895,UniProtKB:P35318	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IGI	UniProtKB:O60896,UniProtKB:P12969:PRO_0000004122	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR	IDA		Human	PMID:7619207
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Calcr	IDA		Mouse	PMID:7988453
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Calcr	IDA		Rat	PMID:7723741\|RGD:2303052
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IDA		Human	PMID:14722252
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	ComplexPortal:CPX-1134,UniProtKB:O60896	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	ComplexPortal:CPX-2173	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	UniProtKB:O60894,UniProtKB:P06881	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	UniProtKB:O60894,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	UniProtKB:O60894,UniProtKB:P12969:PRO_0000004122	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	UniProtKB:O60894,UniProtKB:P35318	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	UniProtKB:O60895,UniProtKB:P12969:PRO_0000004122	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	UniProtKB:O60895,UniProtKB:P35318	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Calcr	IEP		Rat	PMID:23110133\|RGD:151665477
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Calcr	IEP		Rat	PMID:23110133\|RGD:151665477
Biological Process	GO:0038041	cross-receptor inhibition within G protein-coupled receptor heterodimer	CALCR	IPI	UniProtKB:O60896	Human	PMID:14722252
Biological Process	GO:1903131	mononuclear cell differentiation	Calcr	IEP		Rat	PMID:23110133\|RGD:151665477
Biological Process	GO:0030279	negative regulation of ossification	Calcr	IMP	MGI:MGI:3038975	Mouse	PMID:14970190
Biological Process	GO:0001503	ossification	Calcr	IMP	MGI:MGI:3038975	Mouse	PMID:14970190
Biological Process	GO:0030316	osteoclast differentiation	Calcr	IDA		Mouse	PMID:7664679
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	CALCR	IGI	ComplexPortal:CPX-1134,UniProtKB:O60896	Human	PMID:22500019
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0010942	positive regulation of cell death	CALCR	IGI	ComplexPortal:CPX-1134,UniProtKB:O60896	Human	PMID:22500019
Biological Process	GO:0010942	positive regulation of cell death	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Calcr	IDA		Mouse	PMID:9753683
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	CALCR	IGI	UniProtKB:O60896,UniProtKB:P05067:PRO_0000000092	Human	PMID:22500019
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0010628	positive regulation of gene expression	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	CALCR	IGI	ComplexPortal:CPX-1134,UniProtKB:O60896	Human	PMID:22500019
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0010739	positive regulation of protein kinase A signaling	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	CALCR	IGI	ComplexPortal:CPX-1134,UniProtKB:O60896	Human	PMID:22500019
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	CALCR	IGI	UniProtKB:O60896,UniProtKB:P10997:PRO_0000004106	Human	PMID:22500019
Biological Process	GO:0043488	regulation of mRNA stability	Calcr	IDA		Mouse	PMID:9002981
Biological Process	GO:1904645	response to amyloid-beta	CALCR	IGI	UniProtKB:O60896	Human	PMID:22500019
Biological Process	GO:0051384	response to glucocorticoid	CALCR	IDA		Human	PMID:11250927

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.