Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Camk2d

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CAMK2D
- Mouse genes Camk2d
- Rat genes Camk2d
- Zfish genes camk2d1,camk2d2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Camk2d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	CAMK2D	IPI	UniProtKB:P0DP23	Human	PMID:20668654
Molecular Function	GO:0005516	calmodulin binding	CAMK2D	IPI	UniProtKB:P0DP24	Human	PMID:20668654
Molecular Function	GO:0005516	calmodulin binding	CAMK2D	IPI	UniProtKB:P0DP25	Human	PMID:20668654
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	CAMK2D	IDA		Human	PMID:22514276
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	CAMK2D	IDA		Human	PMID:23283722
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Camk2d	IDA		Mouse	MGI:MGI:7327234\|PMID:11972023
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Camk2d	IDA		Rat	PMID:11925434\|RGD:724615
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Camk2d	IDA		Rat	PMID:12676814\|RGD:8656014
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Camk2d	IDA		Rat	PMID:22514276\|RGD:8693364
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Camk2d	IDA		Rat	PMID:23283722\|RGD:8656013
Molecular Function	GO:0042802	identical protein binding	CAMK2D	IPI	UniProtKB:Q13557	Human	PMID:20668654
Molecular Function	GO:0042802	identical protein binding	CAMK2D	IPI	UniProtKB:Q13557	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	CAMK2D	IPI	UniProtKB:Q13557	Human	PMID:31515488
Molecular Function	GO:0050998	nitric-oxide synthase binding	Camk2d	IPI	RGD:3185	Rat	PMID:17293490\|RGD:7240712
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q13554	Human	PMID:20668654
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q13555	Human	PMID:20668654
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q9UQM7	Human	PMID:20668654
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q14524	Human	PMID:22514276
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:O14787	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:O96015	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:P51116	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:P68106	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q53EP0-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q5JZY3-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q8N0Z6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q96BY2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q9Y3B7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q9UQM7	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:P0C6X7:PRO_0000037311	Human	PMID:27519799
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q96PM5	Human	PMID:27519799
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q13554	Human	PMID:29426014
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:O14787	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:O96015	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q8N0Z6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q8N9N5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q9Y3B7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q9UQM7	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q13554	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q13555	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:Q9UQM7	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CAMK2D	IPI	UniProtKB:P61014	Human	PMID:32873725
Molecular Function	GO:0005515	protein binding	Camk2d	IPI	UniProtKB:Q9JJ28	Mouse	MGI:MGI:5512959\|PMID:18588881
Molecular Function	GO:0005515	protein binding	Camk2d	IPI	UniProtKB:E9Q401	Mouse	MGI:MGI:6189492\|PMID:24952909
Molecular Function	GO:0005515	protein binding	Camk2d	IPI	UniProtKB:E9Q401	Mouse	MGI:MGI:6189498\|PMID:20479242
Molecular Function	GO:0005515	protein binding	Camk2d	IPI	UniProtKB:E9PX29	Mouse	PMID:20877009
Molecular Function	GO:0005515	protein binding	Camk2d	IPI	PR:Q8CC27	Mouse	PMID:20877009
Molecular Function	GO:0005515	protein binding	Camk2d	IPI	PR:G5E8K5	Mouse	PMID:20877009
Molecular Function	GO:0005515	protein binding	Camk2d	IPI	RGD:3595	Rat	PMID:12145273\|RGD:1300474
Molecular Function	GO:0042803	protein homodimerization activity	CAMK2D	IPI	UniProtKB:Q13557	Human	PMID:20668654
Molecular Function	GO:0004672	protein kinase activity	Camk2d	IMP		Rat	PMID:22514276\|RGD:8693364
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CAMK2D	IDA		Human	PMID:22514276
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Camk2d	IDA		Mouse	PMID:20877009
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Camk2d	IMP		Mouse	PMID:12660151
Molecular Function	GO:0019871	sodium channel inhibitor activity	CAMK2D	IDA		Human	PMID:22514276
Molecular Function	GO:0031432	titin binding	CAMK2D	IPI	UniProtKB:Q8WZ42	Human	PMID:23283722
Molecular Function	GO:0044325	transmembrane transporter binding	CAMK2D	IPI	UniProtKB:Q14524	Human	PMID:22514276
Molecular Function	GO:0044325	transmembrane transporter binding	Camk2d	IPI	UniProtKB:E9Q401	Mouse	MGI:MGI:3772026\|PMID:12676814
Molecular Function	GO:0044325	transmembrane transporter binding	Camk2d	IPI	UniProtKB:E9Q401	Rat	PMID:12676814\|RGD:8656014
Molecular Function	GO:0044325	transmembrane transporter binding	Camk2d	IDA		Rat	PMID:18205403\|RGD:7175532
Cellular Component	GO:0043194	axon initial segment	Camk2d	IDA		Mouse	PMID:20877009
Cellular Component	GO:0005954	calcium- and calmodulin-dependent protein kinase complex	CAMK2D	IDA		Human	PMID:20668654
Cellular Component	GO:0005737	cytoplasm	Camk2d	IDA		Mouse	PMID:15652482
Cellular Component	GO:0005737	cytoplasm	Camk2d	IDA		Rat	PMID:12676814\|RGD:8656014
Cellular Component	GO:0005829	cytosol	Camk2d	IDA		Rat	PMID:8390994\|RGD:1298725
Cellular Component	GO:0014704	intercalated disc	Camk2d	IDA		Mouse	PMID:20877009
Cellular Component	GO:0016020	membrane	CAMK2D	HDA		Human	PMID:19946888
Cellular Component	GO:0031594	neuromuscular junction	Camk2d	IDA		Mouse	PMID:17873280
Cellular Component	GO:0043025	neuronal cell body	Camk2d	IDA		Mouse	PMID:20877009
Cellular Component	GO:0005634	nucleus	Camk2d	IDA		Mouse	PMID:15652482
Cellular Component	GO:0005634	nucleus	Camk2d	IDA		Rat	PMID:12676814\|RGD:8656014
Cellular Component	GO:0005634	nucleus	Camk2d	IDA		Rat	PMID:9930758\|RGD:2303060
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Camk2d	IDA		Rat	PMID:17293490\|RGD:7240712
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Camk2d	IDA		Rat	PMID:18385282\|RGD:6907067
Cellular Component	GO:0032991	protein-containing complex	Camk2d	IDA		Rat	PMID:22360269\|RGD:7241148
Cellular Component	GO:0030315	T-tubule	Camk2d	IDA		Mouse	PMID:15652482
Biological Process	GO:0006816	calcium ion transport	Camk2d	IDA		Mouse	PMID:15652482
Biological Process	GO:0006816	calcium ion transport	Camk2d	IMP		Mouse	PMID:12660151
Biological Process	GO:0086003	cardiac muscle cell contraction	Camk2d	IDA		Rat	PMID:12676814\|RGD:8656014
Biological Process	GO:0060048	cardiac muscle contraction	Camk2d	IDA		Mouse	PMID:15652482
Biological Process	GO:0061049	cell growth involved in cardiac muscle cell development	Camk2d	IMP		Rat	PMID:21554860\|RGD:6907064
Biological Process	GO:0032469	endoplasmic reticulum calcium ion homeostasis	Camk2d	IDA		Rat	PMID:12676813\|RGD:10047271
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Camk2d	IMP		Mouse	PMID:12660151
Biological Process	GO:0030007	intracellular potassium ion homeostasis	Camk2d	IMP		Rat	PMID:11925434\|RGD:724615
Biological Process	GO:1902306	negative regulation of sodium ion transmembrane transport	CAMK2D	IDA		Human	PMID:22514276
Biological Process	GO:2000650	negative regulation of sodium ion transmembrane transporter activity	CAMK2D	IDA		Human	PMID:22514276
Biological Process	GO:0018105	peptidyl-serine phosphorylation	CAMK2D	IDA		Human	PMID:22514276
Biological Process	GO:0018105	peptidyl-serine phosphorylation	CAMK2D	IDA		Human	PMID:23283722
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Camk2d	IDA		Mouse	PMID:20877009
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Camk2d	IDA		Rat	PMID:12676814\|RGD:8656014
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	CAMK2D	IDA		Human	PMID:22514276
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	CAMK2D	IDA		Human	PMID:23283722
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Camk2d	IDA		Rat	PMID:12676814\|RGD:8656014
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	Camk2d	IMP		Rat	PMID:23702479\|RGD:10047251
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	CAMK2D	IMP		Human	PMID:17179159
Biological Process	GO:2000573	positive regulation of DNA biosynthetic process	Camk2d	IMP		Rat	PMID:17267544\|RGD:2303063
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Camk2d	IMP		Rat	PMID:18385282\|RGD:6907067
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	Camk2d	IMP		Rat	PMID:17267544\|RGD:2303063
Biological Process	GO:0035022	positive regulation of Rac protein signal transduction	Camk2d	IMP		Rat	PMID:18385282\|RGD:6907067
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Camk2d	IMP		Rat	PMID:18385282\|RGD:6907067
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	Camk2d	IMP		Rat	PMID:17267544\|RGD:2303063
Biological Process	GO:0046777	protein autophosphorylation	CAMK2D	IDA		Human	PMID:22514276
Biological Process	GO:0046777	protein autophosphorylation	Camk2d	IMP		Mouse	PMID:12660151
Biological Process	GO:0046777	protein autophosphorylation	Camk2d	IDA		Rat	PMID:11925434\|RGD:724615
Biological Process	GO:0006468	protein phosphorylation	CAMK2D	IDA		Human	PMID:17179159
Biological Process	GO:0006468	protein phosphorylation	CAMK2D	IDA		Human	PMID:23283722
Biological Process	GO:0006468	protein phosphorylation	Camk2d	IDA		Rat	PMID:23283722\|RGD:8656013
Biological Process	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Camk2d	IDA		Rat	PMID:12676813\|RGD:10047271
Biological Process	GO:0098901	regulation of cardiac muscle cell action potential	Camk2d	IDA		Rat	PMID:12676813\|RGD:10047271
Biological Process	GO:0010649	regulation of cell communication by electrical coupling	Camk2d	IDA		Rat	PMID:12676813\|RGD:10047271
Biological Process	GO:0060341	regulation of cellular localization	CAMK2D	IMP		Human	PMID:17179159
Biological Process	GO:0003254	regulation of membrane depolarization	CAMK2D	IDA		Human	PMID:22514276
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	Camk2d	IGI	ComplexPortal:CPX-1134,UniProtKB:P08413,UniProtKB:P11275,UniProtKB:P11730	Rat	PMID:19188609\|RGD:12907552
Biological Process	GO:1901897	regulation of relaxation of cardiac muscle	CAMK2D	IDA		Human	PMID:23283722
Biological Process	GO:1901897	regulation of relaxation of cardiac muscle	Camk2d	IGI	UniProtKB:Q923T9	Mouse	MGI:MGI:5508699\|PMID:23283722
Biological Process	GO:1901897	regulation of relaxation of cardiac muscle	Camk2d	IDA		Rat	PMID:23283722\|RGD:8656013
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Camk2d	IDA		Rat	PMID:12676813\|RGD:10047271
Biological Process	GO:0002028	regulation of sodium ion transport	Camk2d	IDA		Mouse	PMID:20877009
Biological Process	GO:0055119	relaxation of cardiac muscle	Camk2d	IDA		Rat	PMID:12676814\|RGD:8656014
Biological Process	GO:0001666	response to hypoxia	Camk2d	IMP		Rat	PMID:11925434\|RGD:724615

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.