Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CAMKK2
  • Mouse genes Camkk2
  • Rat genes Camkk2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Camkk2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	CAMKK2	IDA		Human	PMID:11395482
Molecular Function	GO:0005516	calmodulin binding	Camkk2	IDA		Rat	PMID:16054095|RGD:2311420
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Camkk2	IDA		Rat	PMID:16054095|RGD:2311420
Molecular Function	GO:0005515	protein binding	Camkk2	IPI	UniProtKB:P49593	Mouse	MGI:MGI:5315357|PMID:15140879
Cellular Component	GO:0005829	cytosol	CAMKK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	CAMKK2	IMP		Human	PMID:26103054
Biological Process	GO:0032147	activation of protein kinase activity	Camkk2	IDA		Rat	PMID:16054095|RGD:2311420
Biological Process	GO:0061762	CAMKK-AMPK signaling cascade	CAMKK2	IMP		Human	PMID:26103054
Biological Process	GO:0001934	positive regulation of protein phosphorylation	CAMKK2	IMP		Human	PMID:26103054
Biological Process	GO:0046777	protein autophosphorylation	CAMKK2	IDA		Human	PMID:11395482
Biological Process	GO:0006468	protein phosphorylation	CAMKK2	IDA		Human	PMID:11395482

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern