Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CAPRIN1
  • Mouse genes Caprin1
  • Rat genes Caprin1
  • Zfish genes caprin1a,caprin1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Caprin1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	CAPRIN1	IDA		Human	PMID:34074792
Molecular Function	GO:0005524	ATP binding	CAPRIN1	IDA		Human	PMID:36040869
Molecular Function	GO:0005509	calcium ion binding	caprin1a	IDA		Zfish	PMID:25331957
Molecular Function	GO:0042802	identical protein binding	caprin1a	IDA		Zfish	PMID:25331957
Molecular Function	GO:0140693	molecular condensate scaffold activity	CAPRIN1	IDA		Human	PMID:31439799
Molecular Function	GO:0140693	molecular condensate scaffold activity	CAPRIN1	IDA		Human	PMID:34074792
Molecular Function	GO:0140693	molecular condensate scaffold activity	CAPRIN1	IDA		Human	PMID:36040869
Molecular Function	GO:0003729	mRNA binding	CAPRIN1	IDA		Human	PMID:17210633
Molecular Function	GO:0003729	mRNA binding	CAPRIN1	IDA		Human	PMID:34074792
Molecular Function	GO:0005515	protein binding	CAPRIN1	IPI	UniProtKB:Q13283	Human	PMID:18005740
Molecular Function	GO:0005515	protein binding	CAPRIN1	IPI	UniProtKB:Q6Y7W6	Human	PMID:20696395
Molecular Function	GO:0005515	protein binding	CAPRIN1	IPI	UniProtKB:Q13283	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CAPRIN1	IPI	UniProtKB:O00571	Human	PMID:28733330
Molecular Function	GO:0005515	protein binding	CAPRIN1	IPI	UniProtKB:Q13283	Human	PMID:34799561
Molecular Function	GO:0005515	protein binding	CAPRIN1	IPI	UniProtKB:Q13283	Human	PMID:34901782
Molecular Function	GO:0003723	RNA binding	CAPRIN1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	CAPRIN1	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Caprin1	IDA		Rat	PMID:20516077|RGD:8554681
Molecular Function	GO:0035591	signaling adaptor activity	CAPRIN1	IDA		Human	PMID:31439799
Molecular Function	GO:0045182	translation regulator activity	CAPRIN1	IDA		Human	PMID:17210633
Molecular Function	GO:0045182	translation regulator activity	CAPRIN1	IDA		Human	PMID:31439799
Molecular Function	GO:0045182	translation regulator activity	CAPRIN1	IDA		Human	PMID:34074792
Cellular Component	GO:0031252	cell leading edge	CAPRIN1	IDA		Human	PMID:28733330
Cellular Component	GO:0005737	cytoplasm	CAPRIN1	IDA		Human	PMID:28733330
Cellular Component	GO:0010494	cytoplasmic stress granule	Caprin1	IDA		Mouse	PMID:21933836
Cellular Component	GO:0010494	cytoplasmic stress granule	Caprin1	IDA		Rat	PMID:20516077|RGD:8554681
Cellular Component	GO:0005829	cytosol	CAPRIN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098978	glutamatergic synapse	Caprin1	IDA		Rat	PMID:15858068|RGD:13702204
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	CAPRIN1	IDA		Human	PMID:31439799
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	CAPRIN1	IDA		Human	PMID:34074792
Cellular Component	GO:0016020	membrane	CAPRIN1	HDA		Human	PMID:19946888
Cellular Component	GO:0000932	P-body	Caprin1	IDA		Rat	PMID:20516077|RGD:8554681
Cellular Component	GO:0098794	postsynapse	Caprin1	IDA		Rat	PMID:15858068|RGD:13702204
Cellular Component	GO:0045202	synapse	Caprin1	IDA		Mouse	PMID:16452087
Cellular Component	GO:0045202	synapse	Caprin1	EXP		Mouse	PMID:16452087
Biological Process	GO:0017148	negative regulation of translation	CAPRIN1	IDA		Human	PMID:31439799
Biological Process	GO:0017148	negative regulation of translation	CAPRIN1	IDA		Human	PMID:34074792
Biological Process	GO:0017148	negative regulation of translation	Caprin1	IDA		Rat	PMID:20516077|RGD:8554681
Biological Process	GO:0140694	non-membrane-bounded organelle assembly	CAPRIN1	IDA		Human	PMID:31439799
Biological Process	GO:0140694	non-membrane-bounded organelle assembly	CAPRIN1	IDA		Human	PMID:34074792
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Caprin1	IMP		Mouse	MGI:MGI:4888105|PMID:20516077
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	Caprin1	IMP		Mouse	MGI:MGI:4888105|PMID:20516077
Biological Process	GO:0106288	regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA	CAPRIN1	IDA		Human	PMID:31439799

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern