Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CAPZB
  • Mouse genes Capzb
  • Rat genes Capzb
  • Zfish genes capzb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Capzb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	CAPZB	IDA		Human	PMID:28493397
Molecular Function	GO:0045296	cadherin binding	CAPZB	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	CAPZB	IPI	UniProtKB:P63261	Human	PMID:28493397
Molecular Function	GO:0005515	protein binding	CAPZB	IPI	UniProtKB:Q6ZU35	Human	PMID:30361697
Molecular Function	GO:0005515	protein binding	Capzb	IPI	UniProtKB:Q9ERD7	Mouse	MGI:MGI:4397629|PMID:19806181
Molecular Function	GO:0005515	protein binding	Capzb	IPI	UniProtKB:Q6JBY9	Mouse	MGI:MGI:5315352|PMID:15850461
Molecular Function	GO:0005515	protein binding	Capzb	IPI	PR:Q9JIY0	Mouse	PMID:22553210
Molecular Function	GO:0005515	protein binding	Capzb	IPI	UniProtKB:P62775	Rat	PMID:15845376|RGD:8554492
Cellular Component	GO:0032279	asymmetric synapse	Capzb	IDA		Mouse	PMID:20545768
Cellular Component	GO:0005903	brush border	Capzb	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0030863	cortical cytoskeleton	Capzb	IDA		Mouse	PMID:18723693
Cellular Component	GO:0043197	dendritic spine	Capzb	IDA		Rat	PMID:20545768|RGD:9685031
Cellular Component	GO:0070062	extracellular exosome	CAPZB	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CAPZB	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	CAPZB	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CAPZB	HDA		Human	PMID:23533145
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Capzb	IDA		Mouse	PMID:20545768
Cellular Component	GO:0030027	lamellipodium	Capzb	IDA		Mouse	PMID:15294161
Cellular Component	GO:0016020	membrane	Capzb	IDA		Mouse	PMID:18723693
Cellular Component	GO:0043025	neuronal cell body	Capzb	IDA		Rat	PMID:15845376|RGD:8554492
Cellular Component	GO:0014069	postsynaptic density	Capzb	IDA		Mouse	PMID:20545768
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Capzb	IDA		Mouse	PMID:20545768
Cellular Component	GO:0097224	sperm connecting piece	Capzb	IDA		Mouse	PMID:30026308
Cellular Component	GO:0071203	WASH complex	CAPZB	IDA		Human	PMID:19922875
Biological Process	GO:0008154	actin polymerization or depolymerization	Capzb	IDA		Mouse	PMID:30026308
Biological Process	GO:0030030	cell projection organization	Capzb	IMP		Mouse	PMID:15294161
Biological Process	GO:0007010	cytoskeleton organization	CAPZB	IMP		Human	PMID:21834987
Biological Process	GO:0030032	lamellipodium assembly	Capzb	IMP		Mouse	PMID:15294161
Biological Process	GO:0055001	muscle cell development	capzb	IMP	ZFIN:ZDB-GENO-180521-1	Zfish	PMID:26758871
Biological Process	GO:0014033	neural crest cell differentiation	capzb	IMP	ZFIN:ZDB-GENO-180521-1	Zfish	PMID:26758871
Biological Process	GO:0001755	neural crest cell migration	capzb	IMP	ZFIN:ZDB-GENO-180521-1	Zfish	PMID:26758871
Biological Process	GO:0022604	regulation of cell morphogenesis	CAPZB	IMP		Human	PMID:21834987

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern