Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CARD11
  • Mouse genes Card11
  • Rat genes
  • Zfish genes card11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Card11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050700	CARD domain binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:11278692
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:12154360
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:16809782
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:P27487	Human	PMID:17287217
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:17948050
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:Q9UDY8	Human	PMID:17948050
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:19118383
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:P48729	Human	PMID:19118383
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:P48729-1	Human	PMID:19118383
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:19444310
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:P70218	Human	PMID:19706536
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:19815501
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:Q13191-1	Human	PMID:19815501
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:21157432
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:22528498
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:Q05655	Human	PMID:22528498
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:Q9UDY8	Human	PMID:22528498
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:Q96EP0	Human	PMID:27777308
Molecular Function	GO:0005515	protein binding	CARD11	IPI	UniProtKB:O95999	Human	PMID:31296852
Molecular Function	GO:0005515	protein binding	Card11	IPI	UniProtKB:O95999	Mouse	PMID:12356734
Molecular Function	GO:0043621	protein self-association	CARD11	IDA		Human	PMID:24074955
Molecular Function	GO:0043621	protein self-association	CARD11	IDA		Human	PMID:31296852
Cellular Component	GO:0032449	CBM complex	CARD11	IDA		Human	PMID:24074955
Cellular Component	GO:0032449	CBM complex	CARD11	IDA		Human	PMID:28628108
Cellular Component	GO:0005737	cytoplasm	CARD11	IDA		Human	PMID:12154360
Cellular Component	GO:0070062	extracellular exosome	CARD11	HDA		Human	PMID:18570454
Cellular Component	GO:0001772	immunological synapse	Card11	IDA		Mouse	PMID:23793062
Cellular Component	GO:0045121	membrane raft	CARD11	IDA		Human	PMID:12154360
Cellular Component	GO:0045121	membrane raft	CARD11	IDA		Human	PMID:17287217
Cellular Component	GO:0005886	plasma membrane	CARD11	IDA		Human	PMID:12154360
Cellular Component	GO:0005886	plasma membrane	Card11	IDA		Mouse	PMID:12867038
Biological Process	GO:0030183	B cell differentiation	Card11	IMP	MGI:MGI:3045950	Mouse	PMID:12818158
Biological Process	GO:0042100	B cell proliferation	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0042100	B cell proliferation	Card11	IMP	MGI:MGI:3045950	Mouse	PMID:12818158
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0048872	homeostasis of number of cells	Card11	IMP	MGI:MGI:3045950	Mouse	PMID:12818158
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	CARD11	IMP		Human	PMID:28628108
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0002377	immunoglobulin production	Card11	IMP	MGI:MGI:3045950	Mouse	PMID:12818158
Biological Process	GO:0032623	interleukin-2 production	Card11	IMP	MGI:MGI:3045950	Mouse	PMID:12818158
Biological Process	GO:0032623	interleukin-2 production	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0046649	lymphocyte activation	Card11	IMP	MGI:MGI:3045950	Mouse	PMID:12818158
Biological Process	GO:0030890	positive regulation of B cell proliferation	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	CARD11	IMP		Human	PMID:12154360
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Card11	IMP		Mouse	MGI:MGI:6695669|PMID:12154356
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0032743	positive regulation of interleukin-2 production	CARD11	IMP		Human	PMID:12154360
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CARD11	IMP		Human	PMID:12154360
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CARD11	IDA		Human	PMID:24074955
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Card11	IMP		Mouse	MGI:MGI:6695669|PMID:12154356
Biological Process	GO:0050870	positive regulation of T cell activation	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	CARD11	IMP		Human	PMID:12154360
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	Card11	IMP		Mouse	MGI:MGI:6695669|PMID:12154356
Biological Process	GO:0051260	protein homooligomerization	CARD11	IDA		Human	PMID:24074955
Biological Process	GO:0051260	protein homooligomerization	CARD11	IDA		Human	PMID:31296852
Biological Process	GO:0045577	regulation of B cell differentiation	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0050776	regulation of immune response	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0045580	regulation of T cell differentiation	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0007165	signal transduction	Card11	IDA		Mouse	PMID:12356734
Biological Process	GO:0042110	T cell activation	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0042110	T cell activation	Card11	IMP	MGI:MGI:3045950	Mouse	PMID:12818158
Biological Process	GO:0031295	T cell costimulation	CARD11	IDA		Human	PMID:17287217
Biological Process	GO:0045061	thymic T cell selection	Card11	IMP	MGI:MGI:3039682	Mouse	PMID:12867038
Biological Process	GO:0038202	TORC1 signaling	CARD11	IMP		Human	PMID:28628108

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern