Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CASC3
  • Mouse genes Casc3
  • Rat genes Casc3
  • Zfish genes casc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Casc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	CASC3	IPI	UniProtKB:O95271	Human	PMID:21478859
Molecular Function	GO:0019899	enzyme binding	CASC3	IPI	UniProtKB:Q9H2K2	Human	PMID:21478859
Molecular Function	GO:0042802	identical protein binding	CASC3	IDA		Human	PMID:12080473
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:14973490
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:14973490
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:16170325
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:16170325
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:16209946
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:16209946
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:16601204
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:16923391
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:16923391
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:16931718
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:16931718
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:18066079
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:18066079
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:19410547
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:19410547
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:19478851
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:19478851
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:20479275
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:20479275
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:22522823
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:22522823
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:23084401
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:23084401
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:Q14147	Human	PMID:25220460
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P61326	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:P38919	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CASC3	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Casc3	IPI	PR:Q9Z108	Mouse	PMID:12843282
Molecular Function	GO:0003723	RNA binding	CASC3	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	CASC3	HDA		Human	PMID:22681889
Molecular Function	GO:0031625	ubiquitin protein ligase binding	CASC3	IPI	UniProtKB:Q9NTX7	Human	PMID:21478859
Cellular Component	GO:0005737	cytoplasm	Casc3	IDA		Mouse	PMID:12843282
Cellular Component	GO:0035145	exon-exon junction complex	CASC3	IPI		Human	PMID:16931718
Cellular Component	GO:0035145	exon-exon junction complex	CASC3	IDA		Human	PMID:16601204
Cellular Component	GO:0031965	nuclear membrane	CASC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CASC3	IDA		Human	PMID:29301961
Cellular Component	GO:0005634	nucleus	Casc3	IDA		Mouse	PMID:12843282
Cellular Component	GO:1990904	ribonucleoprotein complex	Casc3	IDA		Mouse	PMID:12843282
Cellular Component	GO:0071006	U2-type catalytic step 1 spliceosome	CASC3	IDA		Human	PMID:29301961
Biological Process	GO:0008298	intracellular mRNA localization	Casc3	IDA		Mouse	PMID:12843282
Biological Process	GO:0000398	mRNA splicing, via spliceosome	CASC3	IDA		Human	PMID:29301961
Biological Process	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	CASC3	IDA		Human	PMID:19478851

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern