Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CASP7
  • Mouse genes Casp7
  • Rat genes Casp7
  • Zfish genes casp7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Casp7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	Casp7	IDA		Mouse	MGI:MGI:7327228|PMID:35705808
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	Casp7	IDA		Mouse	PMID:15231831
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:17646170
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:19617626
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:21157428
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:22464733
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:23650375
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:23897474
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:24904167
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:27032039
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	CASP7	IDA		Human	PMID:31586028
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	Casp7	IDA		Mouse	MGI:MGI:5306569|PMID:19759058
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	Casp7	IDA		Mouse	PMID:35705808
Molecular Function	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	CASP7	IDA		Human	PMID:11257230
Molecular Function	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	CASP7	IDA		Human	PMID:19581639
Molecular Function	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	Casp7	IDA		Mouse	MGI:MGI:6716960|PMID:25231987
Molecular Function	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	Casp7	IDA		Mouse	PMID:16183742
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:16123041
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:16352606
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:16374543
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:16916640
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:18723680
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:20566630
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:22184066
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IMP		Human	PMID:22253444
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:22451931
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:27889207
Molecular Function	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	CASP7	IDA		Human	PMID:28863261
Molecular Function	GO:0008234	cysteine-type peptidase activity	Casp7	IDA		Rat	PMID:17218406|RGD:1624270
Molecular Function	GO:0008234	cysteine-type peptidase activity	Casp7	IDA		Rat	PMID:18316105|RGD:2311460
Molecular Function	GO:0008233	peptidase activity	CASP7	IDA		Human	PMID:19740745
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:Q13490	Human	PMID:11084335
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P98170	Human	PMID:11257230
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P98170	Human	PMID:11257231
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P10636	Human	PMID:12888622
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P17405	Human	PMID:21157428
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:Q13177	Human	PMID:21555521
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P21673	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P98170	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P83105	Human	PMID:31470122
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P21673	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P43364	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:Q9GZT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:Q86WV1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:Q8N4N3-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CASP7	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	Casp7	IPI	UniProtKB:P11103|UniProtKB:P62270	Mouse	MGI:MGI:5306569|PMID:19759058
Molecular Function	GO:0003723	RNA binding	CASP7	IDA		Human	PMID:31586028
Cellular Component	GO:0005737	cytoplasm	CASP7	IDA		Human	PMID:21555521
Cellular Component	GO:0005829	cytosol	CASP7	IDA		Human	PMID:16352606
Cellular Component	GO:0005829	cytosol	CASP7	IDA		Human	PMID:17167422
Cellular Component	GO:0005829	cytosol	Casp7	IDA		Rat	PMID:18316105|RGD:2311460
Cellular Component	GO:0005615	extracellular space	Casp7	IDA		Mouse	PMID:35705808
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Casp7	IDA		Rat	PMID:18316105|RGD:2311460
Cellular Component	GO:0005634	nucleus	CASP7	IDA		Human	PMID:16374543
Cellular Component	GO:0005634	nucleus	CASP7	IDA		Human	PMID:19617626
Cellular Component	GO:0005634	nucleus	CASP7	IDA		Human	PMID:21555521
Cellular Component	GO:0005634	nucleus	CASP7	IDA		Human	PMID:22464733
Cellular Component	GO:0005634	nucleus	CASP7	IDA		Human	PMID:17167422
Biological Process	GO:0007568	aging	Casp7	IEP		Rat	PMID:16139996|RGD:2311469
Biological Process	GO:0006915	apoptotic process	CASP7	IDA		Human	PMID:17464193
Biological Process	GO:0071222	cellular response to lipopolysaccharide	CASP7	IDA		Human	PMID:22464733
Biological Process	GO:0072734	cellular response to staurosporine	CASP7	IMP		Human	PMID:22253444
Biological Process	GO:0042742	defense response to bacterium	Casp7	IDA		Mouse	MGI:MGI:7327228|PMID:35705808
Biological Process	GO:0097194	execution phase of apoptosis	CASP7	IDA		Human	PMID:16374543
Biological Process	GO:0097194	execution phase of apoptosis	CASP7	IDA		Human	PMID:16916640
Biological Process	GO:0097194	execution phase of apoptosis	CASP7	IDA		Human	PMID:22184066
Biological Process	GO:0097194	execution phase of apoptosis	CASP7	IDA		Human	PMID:31586028
Biological Process	GO:0097194	execution phase of apoptosis	Casp7	IGI	MGI:MGI:107739	Mouse	PMID:16469926
Biological Process	GO:0044346	fibroblast apoptotic process	Casp7	IGI	MGI:MGI:107739	Mouse	PMID:16469926
Biological Process	GO:0007507	heart development	Casp7	IGI	MGI:MGI:107739	Mouse	PMID:16469926
Biological Process	GO:0071887	leukocyte apoptotic process	Casp7	IEP		Rat	PMID:26861981|RGD:13782282
Biological Process	GO:0070227	lymphocyte apoptotic process	Casp7	IMP		Mouse	MGI:MGI:3838704|PMID:19168786
Biological Process	GO:0051402	neuron apoptotic process	Casp7	IDA		Mouse	PMID:15231831
Biological Process	GO:1905686	positive regulation of plasma membrane repair	Casp7	IDA		Mouse	MGI:MGI:7327228|PMID:35705808
Biological Process	GO:0030163	protein catabolic process	CASP7	IDA		Human	PMID:16374543
Biological Process	GO:0030163	protein catabolic process	CASP7	IDA		Human	PMID:22184066
Biological Process	GO:0030163	protein catabolic process	CASP7	IDA		Human	PMID:22464733
Biological Process	GO:0030163	protein catabolic process	Casp7	IDA		Rat	PMID:18316105|RGD:2311460
Biological Process	GO:0051604	protein maturation	CASP7	IDA		Human	PMID:21157428
Biological Process	GO:0051604	protein maturation	Casp7	IDA		Mouse	PMID:35705808
Biological Process	GO:0016485	protein processing	Casp7	IDA		Mouse	PMID:15231831
Biological Process	GO:0006508	proteolysis	CASP7	IDA		Human	PMID:12888622
Biological Process	GO:0009411	response to UV	Casp7	IGI	MGI:MGI:107739	Mouse	PMID:16469926
Biological Process	GO:0051146	striated muscle cell differentiation	Casp7	IEP		Rat	PMID:28899909|RGD:13782277

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern