Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Casr

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CASR
- Mouse genes Casr
- Rat genes Casr
- Zfish genes casr
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Casr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	CASR	IDA		Human	PMID:27434672
Molecular Function	GO:0005509	calcium ion binding	CASR	IDA		Human	PMID:27434672
Molecular Function	GO:0004930	G protein-coupled receptor activity	CASR	IDA		Human	PMID:27434672
Molecular Function	GO:0005178	integrin binding	Casr	IPI	RGD:1310613	Rat	PMID:21969374\|RGD:7205691
Molecular Function	GO:0005178	integrin binding	Casr	IPI	RGD:1311374	Rat	PMID:21969374\|RGD:7205691
Molecular Function	GO:0005178	integrin binding	Casr	IPI	RGD:2923	Rat	PMID:21969374\|RGD:7205691
Molecular Function	GO:0005178	integrin binding	Casr	IPI	RGD:2927	Rat	PMID:21969374\|RGD:7205691
Molecular Function	GO:0005178	integrin binding	Casr	IPI	RGD:628869	Rat	PMID:21969374\|RGD:7205691
Molecular Function	GO:0005515	protein binding	CASR	IPI	UniProtKB:Q15363	Human	PMID:20361938
Molecular Function	GO:0042803	protein homodimerization activity	CASR	IDA		Human	PMID:16740594
Molecular Function	GO:0042803	protein homodimerization activity	CASR	IDA		Human	PMID:27434672
Molecular Function	GO:0019901	protein kinase binding	Casr	IPI	RGD:61925	Rat	PMID:20383739\|RGD:7206836
Molecular Function	GO:0044325	transmembrane transporter binding	Casr	IPI	RGD:61822	Rat	PMID:21084311\|RGD:7206833
Cellular Component	GO:0016324	apical plasma membrane	Casr	IDA		Rat	PMID:22517767\|RGD:7205673
Cellular Component	GO:0030424	axon	Casr	IDA		Rat	PMID:22517767\|RGD:7205673
Cellular Component	GO:0043679	axon terminus	Casr	IDA		Rat	PMID:7724534\|RGD:1298726
Cellular Component	GO:0016323	basolateral plasma membrane	Casr	IDA		Rat	PMID:22517767\|RGD:7205673
Cellular Component	GO:0009986	cell surface	Casr	IDA		Rat	PMID:21969374\|RGD:7205691
Cellular Component	GO:0005737	cytoplasm	Casr	IDA		Rat	PMID:22844268\|RGD:7205442
Cellular Component	GO:0016020	membrane	Casr	IDA		Rat	PMID:22566534\|RGD:7205453
Cellular Component	GO:0043005	neuron projection	Casr	IDA		Rat	PMID:22517767\|RGD:7205673
Cellular Component	GO:0043025	neuronal cell body	Casr	IDA		Rat	PMID:22517767\|RGD:7205673
Cellular Component	GO:0005634	nucleus	Casr	IDA		Rat	PMID:22844268\|RGD:7205442
Cellular Component	GO:0005886	plasma membrane	CASR	IDA		Human	PMID:16740594
Cellular Component	GO:0005886	plasma membrane	CASR	IDA		Human	PMID:17555508
Cellular Component	GO:0005886	plasma membrane	CASR	IDA		Human	PMID:19789209
Cellular Component	GO:0005886	plasma membrane	CASR	IDA		Human	PMID:22789683
Cellular Component	GO:0005886	plasma membrane	CASR	IDA		Human	PMID:25104082
Cellular Component	GO:0005886	plasma membrane	CASR	IDA		Human	PMID:25766501
Cellular Component	GO:0005886	plasma membrane	CASR	IDA		Human	PMID:26386835
Cellular Component	GO:0005886	plasma membrane	CASR	IDA		Human	PMID:8702647
Cellular Component	GO:0005886	plasma membrane	Casr	IDA		Rat	PMID:20117086\|RGD:7206840
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Casr	IDA		Rat	PMID:22192592\|RGD:7207059
Biological Process	GO:0006915	apoptotic process	Casr	IEP		Rat	PMID:20409080\|RGD:7206835
Biological Process	GO:0032782	bile acid secretion	Casr	IDA		Rat	PMID:11071898\|RGD:62420
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	Casr	IMP		Rat	PMID:20117086\|RGD:7206840
Biological Process	GO:0055074	calcium ion homeostasis	casr	IMP	ZFIN:ZDB-MRPHLNO-140401-4	Zfish	PMID:24381181
Biological Process	GO:0055074	calcium ion homeostasis	casr	IMP	ZFIN:ZDB-MRPHLNO-140501-1	Zfish	PMID:24169558
Biological Process	GO:0070509	calcium ion import	CASR	IDA		Human	PMID:20846291
Biological Process	GO:0071333	cellular response to glucose stimulus	Casr	IEP		Rat	PMID:21146545\|RGD:7206831
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	Casr	IEP		Rat	PMID:21088907\|RGD:7206832
Biological Process	GO:0071456	cellular response to hypoxia	Casr	IEP		Rat	PMID:21073657\|RGD:7206834
Biological Process	GO:0071404	cellular response to low-density lipoprotein particle stimulus	Casr	IEP		Rat	PMID:22083546\|RGD:7205681
Biological Process	GO:1901653	cellular response to peptide	Casr	IEP		Rat	PMID:22678567\|RGD:7205670
Biological Process	GO:0071305	cellular response to vitamin D	Casr	IEP		Rat	PMID:21940515\|RGD:7205697
Biological Process	GO:1902476	chloride transmembrane transport	Casr	IDA		Rat	PMID:7816802\|RGD:1298562
Biological Process	GO:0005513	detection of calcium ion	CASR	IDA		Human	PMID:27434672
Biological Process	GO:0005513	detection of calcium ion	Casr	IDA		Rat	PMID:7816802\|RGD:1298562
Biological Process	GO:0060613	fat pad development	Casr	IEP		Rat	PMID:21940515\|RGD:7205697
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:17555508
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:19789209
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:21566075
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:22789683
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:23169696
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:23966241
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:25104082
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:25292184
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:25766501
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:26386835
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IDA		Human	PMID:27434672
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:8636323
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:8702647
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CASR	IMP		Human	PMID:8878438
Biological Process	GO:0006874	intracellular calcium ion homeostasis	CASR	IDA		Human	PMID:27434672
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Casr	IDA		Rat	PMID:12065312\|RGD:628315
Biological Process	GO:0007254	JNK cascade	Casr	IMP		Rat	PMID:15084499\|RGD:1358486
Biological Process	GO:0001503	ossification	Casr	IMP		Rat	PMID:15084499\|RGD:1358486
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Casr	IDA		Rat	PMID:22192592\|RGD:7207059
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	Casr	IMP		Mouse	PMID:17823248
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	Casr	IDA		Mouse	PMID:17823248
Biological Process	GO:0090280	positive regulation of calcium ion import	Casr	IMP		Rat	PMID:22098336\|RGD:7205678
Biological Process	GO:0008284	positive regulation of cell population proliferation	Casr	IMP		Rat	PMID:12700162\|RGD:1298591
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Casr	IDA		Rat	PMID:22192592\|RGD:7207059
Biological Process	GO:0010628	positive regulation of gene expression	Casr	IDA		Mouse	PMID:18794335
Biological Process	GO:0032024	positive regulation of insulin secretion	Casr	IMP		Rat	PMID:22566534\|RGD:7205453
Biological Process	GO:0050927	positive regulation of positive chemotaxis	Casr	IMP		Rat	PMID:20117086\|RGD:7206840
Biological Process	GO:0045907	positive regulation of vasoconstriction	Casr	IMP		Rat	PMID:22098336\|RGD:7205678
Biological Process	GO:0051924	regulation of calcium ion transport	Casr	IDA		Mouse	PMID:17823248
Biological Process	GO:0051592	response to calcium ion	Casr	IEP		Rat	PMID:20431039\|RGD:7205500
Biological Process	GO:0071774	response to fibroblast growth factor	Casr	IEP		Rat	PMID:20431039\|RGD:7205500
Biological Process	GO:0002931	response to ischemia	Casr	IEP		Rat	PMID:21488219\|RGD:7205700
Biological Process	GO:0010038	response to metal ion	Casr	IEP		Rat	PMID:22312704\|RGD:7205674
Biological Process	GO:0014070	response to organic cyclic compound	Casr	IEP		Rat	PMID:19092814\|RGD:7205667
Biological Process	GO:0001501	skeletal system development	casr	IMP	ZFIN:ZDB-MRPHLNO-131120-29	Zfish	PMID:23911792
Biological Process	GO:0042311	vasodilation	Casr	IMP		Rat	PMID:15084499\|RGD:1358486

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.