Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cat

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CAT
- Mouse genes Cat
- Rat genes Cat
- Zfish genes cat
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cat

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004046	aminoacylase activity	Cat	IMP	MGI:MGI:3051232	Mouse	PMID:15178682
Molecular Function	GO:0016209	antioxidant activity	CAT	IDA		Human	PMID:10514471
Molecular Function	GO:0004096	catalase activity	CAT	IDA		Human	PMID:16644728
Molecular Function	GO:0004096	catalase activity	CAT	IDA		Human	PMID:18312938
Molecular Function	GO:0004096	catalase activity	CAT	IDA		Human	PMID:18379038
Molecular Function	GO:0004096	catalase activity	CAT	IDA		Human	PMID:7882369
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Mouse	PMID:12521604
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Mouse	PMID:9600348
Molecular Function	GO:0004096	catalase activity	Cat	IMP	MGI:MGI:3053604	Mouse	PMID:4975476
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Mouse	PMID:17275685
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Mouse	PMID:10617683
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Mouse	PMID:15317809
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Mouse	PMID:12646716
Molecular Function	GO:0004096	catalase activity	Cat	IMP	MGI:MGI:3053604	Mouse	PMID:642030
Molecular Function	GO:0004096	catalase activity	Cat	IMP	MGI:MGI:3053604	Mouse	PMID:5929246
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Rat	PMID:15773229\|RGD:1582149
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Rat	PMID:15777843\|RGD:1582148
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Rat	PMID:15869839\|RGD:1582147
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Molecular Function	GO:0004096	catalase activity	Cat	IDA		Rat	PMID:3455767\|RGD:1299853
Molecular Function	GO:0019899	enzyme binding	CAT	IPI	UniProtKB:Q08426	Human	PMID:16781659
Molecular Function	GO:0020037	heme binding	CAT	IDA		Human	PMID:10656833
Molecular Function	GO:0020037	heme binding	CAT	IDA		Human	PMID:11134921
Molecular Function	GO:0042802	identical protein binding	CAT	IPI	UniProtKB:P04040	Human	PMID:21976670
Molecular Function	GO:0042802	identical protein binding	CAT	IPI	UniProtKB:P04040	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	CAT	IPI	UniProtKB:P04040	Human	PMID:29568061
Molecular Function	GO:0050661	NADP binding	CAT	IDA		Human	PMID:10656833
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	Cat	IDA		Mouse	PMID:11792727
Molecular Function	GO:0042803	protein homodimerization activity	CAT	IDA		Human	PMID:10656833
Cellular Component	GO:0062151	catalase complex	CAT	IPI		Human	PMID:10656833
Cellular Component	GO:0005829	cytosol	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Cellular Component	GO:0005783	endoplasmic reticulum	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Cellular Component	GO:0070062	extracellular exosome	CAT	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Cat	IDA		Rat	PMID:9250541\|RGD:9068473
Cellular Component	GO:0005925	focal adhesion	CAT	HDA		Human	PMID:21423176
Cellular Component	GO:0005794	Golgi apparatus	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CAT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Cellular Component	GO:0016020	membrane	CAT	HDA		Human	PMID:16210410
Cellular Component	GO:0016020	membrane	CAT	HDA		Human	PMID:19946888
Cellular Component	GO:0005758	mitochondrial intermembrane space	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Cellular Component	GO:0005739	mitochondrion	Cat	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005778	peroxisomal membrane	Cat	IDA		Mouse	PMID:12915479
Cellular Component	GO:0005777	peroxisome	CAT	IDA		Human	PMID:8769411
Cellular Component	GO:0005777	peroxisome	CAT	IDA		Human	PMID:18379038
Cellular Component	GO:0005777	peroxisome	CAT	IDA		Human	PMID:19479899
Cellular Component	GO:0005777	peroxisome	CAT	IDA		Human	PMID:2895531
Cellular Component	GO:0005777	peroxisome	CAT	IDA		Human	PMID:9053548
Cellular Component	GO:0005777	peroxisome	Cat	IDA		Mouse	MGI:MGI:5319609\|PMID:17881773
Cellular Component	GO:0005777	peroxisome	Cat	IDA		Mouse	PMID:11156684
Cellular Component	GO:0005777	peroxisome	Cat	IDA		Mouse	PMID:21460186
Cellular Component	GO:0005777	peroxisome	Cat	IDA		Mouse	PMID:17275685
Cellular Component	GO:0005777	peroxisome	Cat	IDA		Mouse	PMID:11829486
Cellular Component	GO:0005777	peroxisome	Cat	IDA		Rat	PMID:14561759\|RGD:1580664
Cellular Component	GO:0005886	plasma membrane	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Cellular Component	GO:0032991	protein-containing complex	CAT	IPI	UniProtKB:P04040	Human	PMID:21976670
Biological Process	GO:0009060	aerobic respiration	Cat	IMP	MGI:MGI:3051232	Mouse	PMID:15178682
Biological Process	GO:0007568	aging	Cat	IEP		Rat	PMID:19966046\|RGD:5130205
Biological Process	GO:0061692	cellular detoxification of hydrogen peroxide	CAT	IDA		Human	PMID:18379038
Biological Process	GO:0098869	cellular oxidant detoxification	Cat	IDA		Mouse	MGI:MGI:3522379\|PMID:15317809
Biological Process	GO:0071363	cellular response to growth factor stimulus	Cat	IEP		Rat	PMID:21276205\|RGD:5130881
Biological Process	GO:0008203	cholesterol metabolic process	Cat	IMP	MGI:MGI:3053604	Mouse	PMID:5087482
Biological Process	GO:0020027	hemoglobin metabolic process	Cat	IMP	MGI:MGI:3053604	Mouse	PMID:8153151
Biological Process	GO:0042744	hydrogen peroxide catabolic process	CAT	IDA		Human	PMID:18379038
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Cat	IDA		Mouse	PMID:9600348
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Cat	IMP	MGI:MGI:3051232	Mouse	PMID:15178682
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Cat	IMP	MGI:MGI:3053604	Mouse	PMID:642030
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Cat	IDA		Mouse	PMID:10617683
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Cat	IDA		Mouse	PMID:17275685
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Cat	IMP		Rat	PMID:14713308\|RGD:1358492
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Biological Process	GO:0001822	kidney development	Cat	IMP		Rat	PMID:22733796\|RGD:7206853
Biological Process	GO:0043066	negative regulation of apoptotic process	CAT	IMP		Human	PMID:16644728
Biological Process	GO:0043066	negative regulation of apoptotic process	Cat	IMP		Rat	PMID:10569634\|RGD:5130878
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	Cat	IDA		Mouse	PMID:9600348
Biological Process	GO:0001649	osteoblast differentiation	CAT	HDA		Human	PMID:16210410
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Cat	IDA		Mouse	PMID:15020231
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Cat	IDA		Mouse	PMID:15020231
Biological Process	GO:0014823	response to activity	Cat	IEP		Rat	PMID:9250541\|RGD:9068473
Biological Process	GO:0046686	response to cadmium ion	Cat	IEP		Rat	PMID:18655190\|RGD:9068930
Biological Process	GO:0046688	response to copper ion	cat	IDA		Zfish	PMID:17855494
Biological Process	GO:0032355	response to estradiol	Cat	IEP		Rat	PMID:25038876\|RGD:9127722
Biological Process	GO:0045471	response to ethanol	Cat	IEP		Rat	PMID:9250541\|RGD:9068473
Biological Process	GO:0070542	response to fatty acid	Cat	IEP		Rat	PMID:23232760\|RGD:9068874
Biological Process	GO:0055093	response to hyperoxia	Cat	IEP		Rat	PMID:19895324\|RGD:5130747
Biological Process	GO:0001666	response to hypoxia	Cat	IMP		Rat	PMID:18270324\|RGD:5130774
Biological Process	GO:0014854	response to inactivity	Cat	IEP		Rat	PMID:15638087\|RGD:9068870
Biological Process	GO:0032868	response to insulin	Cat	IEP		Rat	PMID:20465785\|RGD:9213009
Biological Process	GO:0033591	response to L-ascorbic acid	Cat	IEP		Rat	PMID:20698742\|RGD:9068891
Biological Process	GO:0010288	response to lead ion	Cat	IEP		Rat	PMID:15721881\|RGD:9068900
Biological Process	GO:0009642	response to light intensity	Cat	IEP		Rat	PMID:17514533\|RGD:9107626
Biological Process	GO:0006979	response to oxidative stress	Cat	IMP	MGI:MGI:3051232	Mouse	PMID:15178682
Biological Process	GO:0006979	response to oxidative stress	Cat	IDA		Mouse	PMID:17275685
Biological Process	GO:0006979	response to oxidative stress	Cat	IDA		Rat	PMID:17576767\|RGD:2292202
Biological Process	GO:0010193	response to ozone	Cat	IEP		Rat	PMID:20465785\|RGD:9213009
Biological Process	GO:0080184	response to phenylpropanoid	Cat	IEP		Rat	PMID:18547798\|RGD:9068896
Biological Process	GO:0009314	response to radiation	Cat	IEP		Rat	PMID:20698742\|RGD:9068891
Biological Process	GO:0009314	response to radiation	Cat	IEP		Rat	PMID:22237725\|RGD:9479171
Biological Process	GO:0000302	response to reactive oxygen species	CAT	IMP		Human	PMID:16644728
Biological Process	GO:0000302	response to reactive oxygen species	Cat	IMP		Rat	PMID:14713308\|RGD:1358492
Biological Process	GO:0009636	response to toxic substance	Cat	IEP		Rat	PMID:12225545\|RGD:9068902
Biological Process	GO:0009411	response to UV	Cat	IEP		Rat	PMID:12592055\|RGD:9179775
Biological Process	GO:0033189	response to vitamin A	Cat	IEP		Rat	PMID:23485553\|RGD:9068476
Biological Process	GO:0033197	response to vitamin E	Cat	IEP		Rat	PMID:19641679\|RGD:5130868
Biological Process	GO:0033197	response to vitamin E	Cat	IEP		Rat	PMID:19914224\|RGD:9068475
Biological Process	GO:0009410	response to xenobiotic stimulus	Cat	IEP		Rat	PMID:16131024\|RGD:9068916
Biological Process	GO:0006641	triglyceride metabolic process	Cat	IMP	MGI:MGI:3053604	Mouse	PMID:5087482
Biological Process	GO:0001657	ureteric bud development	Cat	IMP		Rat	PMID:22733796\|RGD:7206853
Biological Process	GO:0009650	UV protection	CAT	IMP		Human	PMID:16644728
Biological Process	GO:0009650	UV protection	CAT	IMP		Human	PMID:17053817

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.