Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cav2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CAV2
- Mouse genes Cav2
- Rat genes Cav2
- Zfish genes cav2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cav2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	Cav2	IPI	UniProtKB:P21708	Rat	PMID:20455999\|RGD:10047313
Molecular Function	GO:0060090	molecular adaptor activity	Cav2	IDA		Mouse	MGI:MGI:5613482\|PMID:12091389
Molecular Function	GO:0051219	phosphoprotein binding	Cav2	IPI	RGD:3046	Rat	PMID:15781236\|RGD:2300104
Molecular Function	GO:0051219	phosphoprotein binding	Cav2	IPI	RGD:70500	Rat	PMID:15781236\|RGD:2300104
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:Q03135	Human	PMID:10212252
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:Q13021	Human	PMID:11294831
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:Q12791	Human	PMID:15703204
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:P00533	Human	PMID:16799092
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:Q15049	Human	PMID:19931615
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:Q03135	Human	PMID:24013648
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:P0DOE7	Human	PMID:25556234
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:Q03135	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	CAV2	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cav2	IPI	UniProtKB:P51906	Mouse	PMID:17715130
Molecular Function	GO:0005515	protein binding	Cav2	IPI	RGD:2281	Rat	PMID:12649076\|RGD:1299267
Molecular Function	GO:0005515	protein binding	Cav2	IPI	RGD:69338	Rat	PMID:16000875\|RGD:2300100
Molecular Function	GO:0005515	protein binding	Cav2	IPI	UniProtKB:P41350	Rat	PMID:18162583\|RGD:8553801
Molecular Function	GO:0046982	protein heterodimerization activity	Cav2	IPI	UniProtKB:P49817	Mouse	MGI:MGI:5613486\|PMID:9361015
Molecular Function	GO:0042803	protein homodimerization activity	CAV2	IDA		Human	PMID:8552590
Molecular Function	GO:0019901	protein kinase binding	Cav2	IDA		Mouse	MGI:MGI:5613482\|PMID:12091389
Molecular Function	GO:0019901	protein kinase binding	Cav2	IPI	UniProtKB:P05480	Mouse	MGI:MGI:5613482\|PMID:12091389
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	Cav2	IDA		Mouse	MGI:MGI:5613482\|PMID:12091389
Molecular Function	GO:0097110	scaffold protein binding	Cav2	IPI	UniProtKB:O55033	Mouse	MGI:MGI:5613482\|PMID:12091389
Molecular Function	GO:0000149	SNARE binding	Cav2	IDA		Rat	PMID:11883949\|RGD:632372
Molecular Function	GO:0019905	syntaxin binding	Cav2	IDA		Rat	PMID:11883949\|RGD:632372
Cellular Component	GO:0002080	acrosomal membrane	Cav2	IDA		Mouse	PMID:19144954
Cellular Component	GO:0005901	caveola	CAV2	IDA		Human	PMID:15703204
Cellular Component	GO:0005901	caveola	CAV2	IDA		Human	PMID:18081315
Cellular Component	GO:0005901	caveola	CAV2	IDA		Human	PMID:24013648
Cellular Component	GO:0005901	caveola	CAV2	IDA		Human	PMID:25556234
Cellular Component	GO:0005901	caveola	CAV2	IDA		Human	PMID:8552590
Cellular Component	GO:0005901	caveola	CAV2	IDA		Human	PMID:9361015
Cellular Component	GO:0005901	caveola	Cav2	IDA		Mouse	PMID:11884617
Cellular Component	GO:0005901	caveola	Cav2	IDA		Rat	PMID:16000875\|RGD:2300100
Cellular Component	GO:0005901	caveola	Cav2	IDA		Rat	PMID:16624992\|RGD:2302992
Cellular Component	GO:0002095	caveolar macromolecular signaling complex	Cav2	IDA		Mouse	PMID:11884617
Cellular Component	GO:0009986	cell surface	Cav2	IDA		Rat	PMID:12649076\|RGD:1299267
Cellular Component	GO:0005737	cytoplasm	Cav2	IDA		Rat	PMID:10887965\|RGD:2300101
Cellular Component	GO:0031410	cytoplasmic vesicle	CAV2	IDA		Human	PMID:22792322
Cellular Component	GO:0005829	cytosol	Cav2	IDA		Rat	PMID:12649076\|RGD:1299267
Cellular Component	GO:0005783	endoplasmic reticulum	Cav2	IDA		Rat	PMID:22607032\|RGD:8661790
Cellular Component	GO:0005925	focal adhesion	CAV2	IDA		Human	PMID:12091389
Cellular Component	GO:0005925	focal adhesion	Cav2	IDA		Mouse	MGI:MGI:5613482\|PMID:12091389
Cellular Component	GO:0005794	Golgi apparatus	Cav2	IDA		Rat	PMID:14528016\|RGD:2300102
Cellular Component	GO:0005794	Golgi apparatus	Cav2	IDA		Rat	PMID:18162583\|RGD:8553801
Cellular Component	GO:0005811	lipid droplet	Cav2	IDA		Rat	PMID:14528016\|RGD:2300102
Cellular Component	GO:0016020	membrane	Cav2	IDA		Mouse	PMID:11316799
Cellular Component	GO:0045121	membrane raft	CAV2	IDA		Human	PMID:11294831
Cellular Component	GO:0045121	membrane raft	Cav2	IDA		Rat	PMID:18162583\|RGD:8553801
Cellular Component	GO:0005635	nuclear envelope	Cav2	IDA		Rat	PMID:20455999\|RGD:10047313
Cellular Component	GO:0005637	nuclear inner membrane	Cav2	IDA		Rat	PMID:20455999\|RGD:10047313
Cellular Component	GO:0005637	nuclear inner membrane	Cav2	IDA		Rat	PMID:22607032\|RGD:8661790
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CAV2	IDA		Human	PMID:18081315
Cellular Component	GO:0005886	plasma membrane	CAV2	IDA		Human	PMID:12743374
Cellular Component	GO:0005886	plasma membrane	CAV2	IDA		Human	PMID:15569306
Cellular Component	GO:0005886	plasma membrane	CAV2	IDA		Human	PMID:15788404
Cellular Component	GO:0005886	plasma membrane	CAV2	IDA		Human	PMID:8552590
Cellular Component	GO:0005886	plasma membrane	Cav2	IDA		Mouse	PMID:12138167
Cellular Component	GO:0005886	plasma membrane	Cav2	IDA		Mouse	PMID:11884617
Cellular Component	GO:0005886	plasma membrane	Cav2	IDA		Rat	PMID:16000875\|RGD:2300100
Cellular Component	GO:0005886	plasma membrane	Cav2	IDA		Rat	PMID:18162583\|RGD:8553801
Cellular Component	GO:0044853	plasma membrane raft	CAV2	IDA		Human	PMID:15569306
Cellular Component	GO:0032991	protein-containing complex	CAV2	IDA		Human	PMID:24013648
Cellular Component	GO:0032991	protein-containing complex	Cav2	IDA		Mouse	MGI:MGI:5613482\|PMID:12091389
Cellular Component	GO:0032991	protein-containing complex	Cav2	IDA		Rat	PMID:12649076\|RGD:1299267
Cellular Component	GO:0032991	protein-containing complex	Cav2	IDA		Rat	PMID:15781236\|RGD:2300104
Cellular Component	GO:0032991	protein-containing complex	Cav2	IDA		Rat	PMID:16000875\|RGD:2300100
Cellular Component	GO:0030133	transport vesicle	CAV2	IDA		Human	GO_REF:0000054
Biological Process	GO:0071711	basement membrane organization	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:11884617
Biological Process	GO:0070836	caveola assembly	CAV2	IMP		Human	PMID:12633858
Biological Process	GO:0070836	caveola assembly	CAV2	IDA		Human	PMID:12743374
Biological Process	GO:0008283	cell population proliferation	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:17200204
Biological Process	GO:0007268	chemical synaptic transmission	Cav2	IDA		Rat	PMID:11883949\|RGD:632372
Biological Process	GO:0007029	endoplasmic reticulum organization	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:17200204
Biological Process	GO:0001935	endothelial cell proliferation	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:11884617
Biological Process	GO:0001935	endothelial cell proliferation	Cav2	IGI	MGI:MGI:98728	Mouse	PMID:21832243
Biological Process	GO:0008286	insulin receptor signaling pathway	CAV2	IDA		Human	PMID:20455999
Biological Process	GO:0008286	insulin receptor signaling pathway	Cav2	IDA		Rat	PMID:20455999\|RGD:10047313
Biological Process	GO:0007005	mitochondrion organization	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:17200204
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:11884617
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	Cav2	IMP		Rat	PMID:21807947\|RGD:6784524
Biological Process	GO:0014859	negative regulation of skeletal muscle cell proliferation	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:17200204
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Cav2	IGI	MGI:MGI:98728	Mouse	PMID:21832243
Biological Process	GO:0044794	positive regulation by host of viral process	CAV2	IMP		Human	PMID:25556234
Biological Process	GO:0060161	positive regulation of dopamine receptor signaling pathway	CAV2	IMP		Human	PMID:15569306
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	Cav2	IGI	MGI:MGI:98728	Mouse	PMID:21832243
Biological Process	GO:0043547	positive regulation of GTPase activity	CAV2	IDA		Human	PMID:8552590
Biological Process	GO:0043410	positive regulation of MAPK cascade	CAV2	IDA		Human	PMID:20455999
Biological Process	GO:0043410	positive regulation of MAPK cascade	Cav2	IDA		Rat	PMID:20455999\|RGD:10047313
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Cav2	IDA		Rat	PMID:20455999\|RGD:10047313
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	Cav2	IDA		Rat	PMID:20455999\|RGD:10047313
Biological Process	GO:0019065	receptor-mediated endocytosis of virus by host cell	CAV2	IGI	UniProtKB:O60840	Human	PMID:21047970
Biological Process	GO:0007088	regulation of mitotic nuclear division	CAV2	IEP		Human	PMID:18081315
Biological Process	GO:0014856	skeletal muscle cell proliferation	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:17200204
Biological Process	GO:0048741	skeletal muscle fiber development	Cav2	IMP	MGI:MGI:2180372	Mouse	PMID:17200204
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Cav2	IGI	MGI:MGI:98728	Mouse	PMID:21832243
Biological Process	GO:0048278	vesicle docking	CAV2	IDA		Human	PMID:12743374
Biological Process	GO:0006906	vesicle fusion	CAV2	IDA		Human	PMID:12743374
Biological Process	GO:0016050	vesicle organization	CAV2	IDA		Human	PMID:12743374
Biological Process	GO:0019076	viral release from host cell	CAV2	IMP		Human	PMID:25556234

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.