Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBFA2T2
  • Mouse genes Cbfa2t2
  • Rat genes Cbfa2t2
  • Zfish genes cbfa2t2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbfa2t2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CBFA2T2	IPI	UniProtKB:Q99750	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CBFA2T2	IPI	UniProtKB:Q99750	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	CBFA2T2	IPI	UniProtKB:Q9GZV8	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	CBFA2T2	IPI	UniProtKB:Q99750	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CBFA2T2	IPI	UniProtKB:P17987	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBFA2T2	IPI	UniProtKB:Q9GZV8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBFA2T2	IPI	UniProtKB:Q9P0J1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBFA2T2	IPI	UniProtKB:Q9GZV8	Human	PMID:27281218
Molecular Function	GO:0005515	protein binding	Cbfa2t2	IPI	UniProtKB:P22091	Mouse	MGI:MGI:5508258|PMID:16407974
Molecular Function	GO:0005515	protein binding	Cbfa2t2	IPI	PR:Q60974	Mouse	PMID:16227606
Molecular Function	GO:0005515	protein binding	Cbfa2t2	IPI	PR:P15806	Mouse	PMID:19799863
Molecular Function	GO:0005515	protein binding	Cbfa2t2	IPI	PR:Q60520	Mouse	PMID:16227606
Molecular Function	GO:0005515	protein binding	Cbfa2t2	IPI	PR:O88895	Mouse	PMID:16227606
Molecular Function	GO:0005515	protein binding	Cbfa2t2	IPI	PR:P22091	Mouse	PMID:19799863
Molecular Function	GO:0005515	protein binding	Cbfa2t2	IPI	PR:O54972	Mouse	PMID:19799863
Molecular Function	GO:0003714	transcription corepressor activity	CBFA2T2	IDA		Human	PMID:19026687
Molecular Function	GO:0003714	transcription corepressor activity	Cbfa2t2	IDA		Mouse	PMID:16227606
Cellular Component	GO:0005634	nucleus	CBFA2T2	IDA		Human	PMID:19026687
Biological Process	GO:0030855	epithelial cell differentiation	Cbfa2t2	IMP	MGI:MGI:3607923	Mouse	PMID:16227606
Biological Process	GO:0060575	intestinal epithelial cell differentiation	Cbfa2t2	IMP		Mouse	MGI:MGI:5629454|PMID:25398765
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CBFA2T2	IDA		Human	PMID:23251453
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cbfa2t2	IDA		Mouse	PMID:16227606
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	Cbfa2t2	IMP		Mouse	MGI:MGI:5629454|PMID:25398765
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbfa2t2	IGI	MGI:MGI:98510	Mouse	PMID:19799863
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbfa2t2	IGI	MGI:MGI:1338013	Mouse	PMID:19799863
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbfa2t2	IGI	MGI:MGI:98480	Mouse	PMID:19799863
Biological Process	GO:0010976	positive regulation of neuron projection development	CBFA2T2	IDA		Human	PMID:19026687

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern