Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBLB
  • Mouse genes Cblb
  • Rat genes Cblb
  • Zfish genes cblb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cblb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P46109	Human	PMID:10022120
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q96B97	Human	PMID:12177062
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:12577067
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:O43639	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9H8Y8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9Y5K6	Human	PMID:17020880
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9ULH1	Human	PMID:17255943
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q96B97	Human	PMID:18680311
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q96B97	Human	PMID:19268472
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P46108	Human	PMID:19380743
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q8IZP0	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:21706016
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q96B97	Human	PMID:23663663
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9Y5K6	Human	PMID:23663663
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P16333	Human	PMID:25218436
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:O43639	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:O76003	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q8TF42	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9H8Y8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P06241-3	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P46108	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P46109	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:O43639	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P55345	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:O43639	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P22681	Human	PMID:29237719
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q8IY31	Human	PMID:29237719
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q5S007	Human	PMID:29513927
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9H8Y8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:O14972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:O94875-10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P06241-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P07947	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P57075-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q13882	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q8TF42	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q96B97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9UKW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:O75190	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P00441	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P35240-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P35637	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:P62993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q00403	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q01658	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q5S007	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q6NUL7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBLB	IPI	UniProtKB:Q9Y5Q9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cblb	IPI	UniProtKB:P13379	Mouse	MGI:MGI:5825410|PMID:27474268
Molecular Function	GO:0005515	protein binding	Cblb	IPI	UniProtKB:P22366|UniProtKB:Q80UF7	Mouse	MGI:MGI:4819286|PMID:20639876
Molecular Function	GO:0005515	protein binding	Cblb	IPI	UniProtKB:Q60631	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Cblb	IPI	PR:P47941	Mouse	PMID:12697763
Molecular Function	GO:0019901	protein kinase binding	Cblb	IPI	RGD:621017	Rat	PMID:14531861|RGD:2306284
Cellular Component	GO:0005829	cytosol	CBLB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045121	membrane raft	Cblb	IDA		Rat	PMID:14604964|RGD:2306287
Cellular Component	GO:0005654	nucleoplasm	CBLB	IDA		Human	GO_REF:0000052
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	Cblb	IMP	MGI:MGI:2180572	Mouse	PMID:14973438
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Cblb	IEP		Rat	PMID:14715702|RGD:2306285
Biological Process	GO:0006955	immune response	Cblb	IMP	MGI:MGI:2180570	Mouse	PMID:11070165
Biological Process	GO:0035556	intracellular signal transduction	Cblb	IMP	MGI:MGI:2180570	Mouse	PMID:11070165
Biological Process	GO:0043066	negative regulation of apoptotic process	Cblb	IMP		Rat	PMID:19546888|RGD:11038823
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	Cblb	IMP	MGI:MGI:2180572	Mouse	PMID:14973438
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	Cblb	IMP	MGI:MGI:2180572	Mouse	PMID:14738763
Biological Process	GO:0018193	peptidyl-amino acid modification	Cblb	IDA		Mouse	PMID:12697763
Biological Process	GO:0045732	positive regulation of protein catabolic process	Cblb	IMP	MGI:MGI:2180572	Mouse	PMID:14973438
Biological Process	GO:0031398	positive regulation of protein ubiquitination	Cblb	IDA		Mouse	PMID:12697763
Biological Process	GO:0002669	positive regulation of T cell anergy	Cblb	IMP	MGI:MGI:2180572	Mouse	PMID:14973438
Biological Process	GO:0030163	protein catabolic process	Cblb	IMP	MGI:MGI:2180572	Mouse	PMID:14973438
Biological Process	GO:0030155	regulation of cell adhesion	Cblb	IMP		Mouse	PMID:12697763
Biological Process	GO:0043087	regulation of GTPase activity	Cblb	IMP		Mouse	PMID:12697763
Biological Process	GO:2000583	regulation of platelet-derived growth factor receptor-alpha signaling pathway	Cblb	IMP		Mouse	MGI:MGI:6108066|PMID:29237719
Biological Process	GO:0043393	regulation of protein binding	Cblb	IMP		Mouse	PMID:12697763
Biological Process	GO:0009629	response to gravity	Cblb	IEP		Rat	PMID:14715702|RGD:2306285
Biological Process	GO:0009725	response to hormone	Cblb	IEP		Rat	PMID:16984225|RGD:2306289
Biological Process	GO:0007165	signal transduction	Cblb	IDA		Rat	PMID:12118252|RGD:625457
Biological Process	GO:0042110	T cell activation	Cblb	IMP	MGI:MGI:2180570	Mouse	PMID:11070165
Biological Process	GO:0002870	T cell anergy	Cblb	IMP	MGI:MGI:2180572	Mouse	PMID:14973438
Biological Process	GO:0050852	T cell receptor signaling pathway	Cblb	IMP		Mouse	PMID:12697763

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern