Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBLIF
  • Mouse genes Cblif
  • Rat genes Cblif
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cblif

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140355	cargo receptor ligand activity	Cblif	IDA		Mouse	PMID:14321840
Molecular Function	GO:0031419	cobalamin binding	CBLIF	IDA		Human	PMID:14695536
Molecular Function	GO:0031419	cobalamin binding	Cblif	IDA		Mouse	PMID:14321840
Molecular Function	GO:0031419	cobalamin binding	Cblif	IDA		Rat	PMID:7150665|RGD:1624372
Molecular Function	GO:0140104	molecular carrier activity	Cblif	IDA		Mouse	PMID:14321840
Molecular Function	GO:0005515	protein binding	CBLIF	IPI	UniProtKB:O60494	Human	PMID:20237569
Molecular Function	GO:0005515	protein binding	CBLIF	IPI	UniProtKB:A1A5C7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLIF	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLIF	IPI	UniProtKB:P30825	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLIF	IPI	UniProtKB:Q8TBB6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLIF	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBLIF	IPI	UniProtKB:Q9UKG4	Human	PMID:32296183
Cellular Component	GO:0016324	apical plasma membrane	CBLIF	IDA		Human	PMID:8886952
Cellular Component	GO:0005768	endosome	CBLIF	IDA		Human	PMID:8886952
Cellular Component	GO:0005615	extracellular space	CBLIF	IDA		Human	PMID:14695536
Cellular Component	GO:0005615	extracellular space	Cblif	IDA		Mouse	PMID:14321840
Cellular Component	GO:0005902	microvillus	CBLIF	IDA		Human	PMID:8886952
Biological Process	GO:0009235	cobalamin metabolic process	Cblif	IDA		Rat	PMID:14166172|RGD:1624368
Biological Process	GO:0015889	cobalamin transport	CBLIF	IMP		Human	PMID:15738392
Biological Process	GO:0015889	cobalamin transport	Cblif	IMP	MGI:MGI:4363945	Mouse	PMID:24911144

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern