Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBX2
  • Mouse genes Cbx2
  • Rat genes Cbx2
  • Zfish genes cbx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Cbx2	IDA		Mouse	PMID:16687444
Molecular Function	GO:0035064	methylated histone binding	Cbx2	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Molecular Function	GO:0005515	protein binding	CBX2	IPI	UniProtKB:Q99750	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CBX2	IPI	UniProtKB:Q99750	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	CBX2	IPI	UniProtKB:P0C7H8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX2	IPI	UniProtKB:P0DJD3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX2	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX2	IPI	UniProtKB:P60411	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX2	IPI	UniProtKB:Q15415	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX2	IPI	UniProtKB:Q6P158	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Cbx2	IPI	UniProtKB:Q8CCI5	Mouse	MGI:MGI:1927299|PMID:10369680
Molecular Function	GO:0005515	protein binding	Cbx2	IPI	UniProtKB:Q60848	Mouse	MGI:MGI:6092708|PMID:17726103
Molecular Function	GO:0005515	protein binding	Cbx2	IPI	PR:P25916	Mouse	PMID:9367786
Cellular Component	GO:0000791	euchromatin	Cbx2	IDA		Mouse	PMID:18311137
Cellular Component	GO:0000792	heterochromatin	Cbx2	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Cellular Component	GO:0000792	heterochromatin	Cbx2	IDA		Mouse	PMID:18311137
Cellular Component	GO:0005654	nucleoplasm	CBX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CBX2	IDA		Human	PMID:21282530
Cellular Component	GO:0005634	nucleus	Cbx2	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Cellular Component	GO:0031519	PcG protein complex	CBX2	IDA		Human	PMID:21282530
Cellular Component	GO:0031519	PcG protein complex	Cbx2	IDA		Mouse	PMID:9312051
Cellular Component	GO:0031519	PcG protein complex	Cbx2	IDA		Mouse	PMID:17001316
Cellular Component	GO:0035102	PRC1 complex	CBX2	IDA		Human	PMID:12167701
Cellular Component	GO:0035102	PRC1 complex	CBX2	IDA		Human	PMID:19636380
Biological Process	GO:0045137	development of primary sexual characteristics	CBX2	IMP		Human	PMID:19361780
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CBX2	IMP		Human	PMID:21282530
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbx2	IDA		Mouse	PMID:9367786
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbx2	IDA		Mouse	PMID:9312051

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern