Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBX3
  • Mouse genes Cbx3
  • Rat genes Cbx3,LOC688980
  • Zfish genes cbx3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Cbx3	IPI	UniProtKB:Q60707	Mouse	MGI:MGI:6710296|PMID:33795231
Molecular Function	GO:0019899	enzyme binding	CBX3	IPI	UniProtKB:Q86Y97	Human	PMID:19486527
Molecular Function	GO:1990226	histone methyltransferase binding	CBX3	IPI	UniProtKB:Q86Y97	Human	PMID:19486527
Molecular Function	GO:0042802	identical protein binding	CBX3	IPI	UniProtKB:Q13185	Human	PMID:19486527
Molecular Function	GO:0042802	identical protein binding	CBX3	IPI	UniProtKB:Q13185	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q13263	Human	PMID:10330177
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9H081	Human	PMID:15502821
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P68431	Human	PMID:16415788
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q969R5	Human	PMID:17540172
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9Y468	Human	PMID:17540172
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q86Y97	Human	PMID:19486527
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q7Z3K3	Human	PMID:20850016
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q96JM3	Human	PMID:20850016
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P68431	Human	PMID:20871592
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q13263	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q8IWI9	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9H4L7	Human	PMID:21549307
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q13263	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q5T3J3	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q6IQ32	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9H2P0	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q14166	Human	PMID:23251473
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q5T3J3	Human	PMID:23542155
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q5ZUS4	Human	PMID:23797873
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:O43463	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P68431	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q5T3J3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q86Y97	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q8IWI9	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9H2P0	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9H967	Human	PMID:27248496
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:O43463	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q13263	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q5T3J3	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q6IQ32	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q8IWI9	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q8ND82	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9BWN1	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9H2P0	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:O14978	Human	PMID:32051553
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:O43463	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P23497-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P28838	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P52815	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q5T3J3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q6IQ32	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q6N043-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q8ND82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q99988	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9BWN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q9Y4B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:Q14739	Human	PMID:8663349
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P23497-1	Human	PMID:9636146
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P23497-2	Human	PMID:9636146
Molecular Function	GO:0005515	protein binding	CBX3	IPI	UniProtKB:P23497-3	Human	PMID:9636147
Molecular Function	GO:0005515	protein binding	Cbx3	IPI	UniProtKB:O54943	Mouse	MGI:MGI:5569417|PMID:24413057
Molecular Function	GO:0005515	protein binding	Cbx3	IPI	UniProtKB:Q13263	Mouse	MGI:MGI:3687661|PMID:10330177
Molecular Function	GO:0005515	protein binding	Cbx3	IPI	PR:Q6P926	Mouse	PMID:18418073
Molecular Function	GO:0005515	protein binding	Cbx3	IPI	PR:Q5SEK5	Mouse	PMID:15322135
Molecular Function	GO:0019904	protein domain specific binding	CBX3	IPI	UniProtKB:Q14739	Human	PMID:8663349
Molecular Function	GO:0019904	protein domain specific binding	CBX3	IPI	UniProtKB:P23497	Human	PMID:9636147
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Cbx3	IDA		Mouse	MGI:MGI:5569417|PMID:24413057
Molecular Function	GO:0001221	transcription coregulator binding	CBX3	IPI	UniProtKB:Q9H2P0	Human	PMID:29795351
Cellular Component	GO:0000785	chromatin	CBX3	IDA		Human	PMID:11101528
Cellular Component	GO:0000785	chromatin	Cbx3	IDA		Mouse	PMID:16880268
Cellular Component	GO:0061793	chromatin lock complex	CBX3	IPI		Human	PMID:17540172
Cellular Component	GO:0010369	chromocenter	Cbx3	IDA		Mouse	PMID:15322135
Cellular Component	GO:0000775	chromosome, centromeric region	CBX3	IDA		Human	PMID:10504293
Cellular Component	GO:0000781	chromosome, telomeric region	CBX3	HDA		Human	PMID:19135898
Cellular Component	GO:0000779	condensed chromosome, centromeric region	Cbx3	IDA		Mouse	MGI:MGI:3777546|PMID:11124534
Cellular Component	GO:0000791	euchromatin	CBX3	IDA		Human	PMID:11124534
Cellular Component	GO:0000792	heterochromatin	CBX3	IDA		Human	PMID:11124534
Cellular Component	GO:0000792	heterochromatin	Cbx3	IDA		Mouse	PMID:10562550
Cellular Component	GO:0005635	nuclear envelope	Cbx3	IDA		Mouse	MGI:MGI:3777526|PMID:11101528
Cellular Component	GO:0005634	nucleus	CBX3	IDA		Human	PMID:17540172
Cellular Component	GO:0005634	nucleus	Cbx3	IDA		Mouse	PMID:20219459
Cellular Component	GO:0005634	nucleus	Cbx3	IDA		Mouse	PMID:15469996
Cellular Component	GO:0005634	nucleus	Cbx3	IDA		Rat	PMID:21368868|RGD:5507827
Cellular Component	GO:0005721	pericentric heterochromatin	Cbx3	IDA		Mouse	MGI:MGI:3777545|PMID:16287503
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	CBX3	IDA		Human	PMID:29795351
Cellular Component	GO:0035985	senescence-associated heterochromatin focus	Cbx3	IDA		Rat	PMID:21368868|RGD:5507827
Cellular Component	GO:0090734	site of DNA damage	CBX3	IMP		Human	PMID:27248496
Cellular Component	GO:0005819	spindle	CBX3	IDA		Human	PMID:11101528
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Cbx3	IEP		Rat	PMID:21368868|RGD:5507827
Biological Process	GO:0006974	DNA damage response	CBX3	IMP		Human	PMID:27248496
Biological Process	GO:0031507	heterochromatin formation	CBX3	IDA		Human	PMID:17540172
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CBX3	IMP		Human	PMID:17540172
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CBX3	IDA		Human	PMID:9636147
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CBX3	IMP		Human	PMID:9636147
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cbx3	IDA		Mouse	PMID:10562550

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern