Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBX4
  • Mouse genes Cbx4
  • Rat genes Cbx4
  • Zfish genes cbx4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbx4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Cbx4	IDA		Mouse	PMID:17392792
Molecular Function	GO:0019899	enzyme binding	CBX4	IPI	UniProtKB:P35520	Human	PMID:17087506
Molecular Function	GO:0035064	methylated histone binding	Cbx4	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Molecular Function	GO:0051219	phosphoprotein binding	Cbx4	IPI	PR:P25916	Mouse	PMID:9367786
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q99496	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P35226	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q9HC52	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:O88509	Human	PMID:18567530
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P35226	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P63165	Human	PMID:20098713
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q13363	Human	PMID:20098713
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P35226	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P31946	Human	PMID:22078878
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P35226	Human	PMID:22078878
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q16665	Human	PMID:24434214
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q9HC52	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P35226	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q99496	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q9HC52	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:G2XKQ0	Human	PMID:27211601
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P35226	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q99496	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:Q13363	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:O75626	Human	PMID:28842558
Molecular Function	GO:0005515	protein binding	CBX4	IPI	UniProtKB:P35226	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	Cbx4	IPI	PR:P25916	Mouse	PMID:9367786
Molecular Function	GO:0003727	single-stranded RNA binding	Cbx4	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Molecular Function	GO:0032183	SUMO binding	CBX4	IDA		Human	PMID:20176810
Molecular Function	GO:0032183	SUMO binding	Cbx4	IDA		Mouse	PMID:20176810
Molecular Function	GO:0061665	SUMO ligase activity	CBX4	IDA		Human	PMID:27068747
Molecular Function	GO:0019789	SUMO transferase activity	CBX4	EXP		Human	PMID:12679040
Molecular Function	GO:0019789	SUMO transferase activity	CBX4	EXP		Human	PMID:20098713
Molecular Function	GO:0019789	SUMO transferase activity	CBX4	EXP		Human	PMID:20176810
Molecular Function	GO:0019789	SUMO transferase activity	CBX4	EXP		Human	PMID:22467880
Molecular Function	GO:0019789	SUMO transferase activity	CBX4	EXP		Human	PMID:23404503
Molecular Function	GO:0019789	SUMO transferase activity	Cbx4	EXP		Mouse	MGI:MGI:3759163|PMID:17439403
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Cbx4	IDA		Mouse	PMID:20417598
Cellular Component	GO:0016604	nuclear body	CBX4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	Cbx4	IDA		Mouse	PMID:20417598
Cellular Component	GO:0005654	nucleoplasm	CBX4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CBX4	IDA		Human	PMID:21282530
Cellular Component	GO:0005634	nucleus	CBX4	IDA		Human	PMID:27068747
Cellular Component	GO:0005634	nucleus	CBX4	IDA		Human	PMID:9367786
Cellular Component	GO:0005634	nucleus	Cbx4	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Cellular Component	GO:0031519	PcG protein complex	CBX4	IDA		Human	PMID:21282530
Cellular Component	GO:0035102	PRC1 complex	CBX4	IDA		Human	PMID:12167701
Cellular Component	GO:0035102	PRC1 complex	CBX4	IDA		Human	PMID:19636380
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CBX4	IDA		Human	PMID:18567530
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CBX4	IMP		Human	PMID:21282530
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbx4	IGI	MGI:MGI:1923076	Mouse	PMID:20417598
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbx4	IDA		Mouse	PMID:9367786
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cbx4	IMP		Mouse	PMID:17392792
Biological Process	GO:0016925	protein sumoylation	Cbx4	IMP		Mouse	PMID:20176810

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern