Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBX5
  • Mouse genes Cbx5
  • Rat genes Cbx5
  • Zfish genes cbx5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbx5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Cbx5	IDA		Mouse	PMID:10318760
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Cbx5	IPI	UniProtKB:Q99N13	Mouse	MGI:MGI:4359370|PMID:12242305
Molecular Function	GO:0042826	histone deacetylase binding	Cbx5	IPI	UniProtKB:Q9UQL6	Mouse	MGI:MGI:4359370|PMID:12242305
Molecular Function	GO:0042802	identical protein binding	CBX5	IPI	UniProtKB:P45973	Human	PMID:18716626
Molecular Function	GO:0042802	identical protein binding	CBX5	IPI	UniProtKB:P45973	Human	PMID:21888893
Molecular Function	GO:0042802	identical protein binding	Cbx5	IPI	PR:Q61686	Mouse	PMID:8978696
Molecular Function	GO:0035064	methylated histone binding	CBX5	IDA		Human	PMID:19783980
Molecular Function	GO:0035064	methylated histone binding	CBX5	IDA		Human	PMID:21029866
Molecular Function	GO:0035064	methylated histone binding	Cbx5	IPI	PR:000045397	Mouse	PMID:16127177
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13263	Human	PMID:10330177
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P46100	Human	PMID:10699177
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:12711603
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9UIS9	Human	PMID:12711603
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9H081	Human	PMID:15502821
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P23497	Human	PMID:15882967
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P46100	Human	PMID:15882967
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13111	Human	PMID:15882967
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13263	Human	PMID:15882967
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q14739	Human	PMID:15882967
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q6KC79	Human	PMID:15882967
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BWN1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P68431	Human	PMID:16415788
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5FBB7	Human	PMID:18716626
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P68431	Human	PMID:19498464
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13111	Human	PMID:19498464
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13263	Human	PMID:19498464
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q7Z3K3	Human	PMID:19498464
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9UIS9	Human	PMID:19498464
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q00839	Human	PMID:19617346
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q8TBE0	Human	PMID:19666599
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P84243	Human	PMID:19834512
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5SSJ5	Human	PMID:20042602
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13111	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13263	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5FBB7	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5T3J3	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q7Z3K3	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q96IY1	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BQF6	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BWN1	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9H2P0	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9NQS7	Human	PMID:20562864
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q7Z3K3	Human	PMID:20850016
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q96JM3	Human	PMID:20850016
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P68431	Human	PMID:20871592
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5FBB7	Human	PMID:21346195
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9NQS7	Human	PMID:21346195
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BZ95	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P62805	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13263	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q16695	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9H2P0	Human	PMID:21888893
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5T3J3	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5T3J3	Human	PMID:23542155
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5ZUS4	Human	PMID:23797873
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BQF6	Human	PMID:24018422
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P62805	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13111	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13263	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5FBB7	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q7Z3K3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q96IY1	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P68431	Human	PMID:25281560
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:25931448
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q14191	Human	PMID:25931448
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P23497-2	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9H967	Human	PMID:27248496
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13111	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q13263	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5T3J3	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q7Z3K3	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q96IY1	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BQF6	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BWN1	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9H2P0	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O15273	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P68431	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BWN1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P62805	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q16695	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BWN1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O14978	Human	PMID:32051553
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O15273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P23497-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P28838	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q5T3J3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q6N043-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q8ND82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BWN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O43463	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O75143-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P01106	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P09471	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P25490	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q07869	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q14728	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q16560-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q8N448	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q8NCS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q8TBE0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q96IY1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BZ95	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9BZ95-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9NP61	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9NUD9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9UMR2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9Y228	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q14739	Human	PMID:8663349
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:O35892	Human	PMID:9636146
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P23497-1	Human	PMID:9636146
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P23497-2	Human	PMID:9636146
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P23497	Human	PMID:9636147
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:P23497-3	Human	PMID:9636147
Molecular Function	GO:0005515	protein binding	CBX5	IPI	UniProtKB:Q9NQS7	Human	PMID:9864353
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	UniProtKB:Q6PR54	Mouse	MGI:MGI:5584328|PMID:24735877
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	UniProtKB:Q8BUH8	Mouse	MGI:MGI:5918100|PMID:22388734
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	UniProtKB:Q3TYX3	Mouse	MGI:MGI:6709288|PMID:28250819
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q3TKT4	Mouse	PMID:8978696
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q64127	Mouse	PMID:8978696
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q5SEK5	Mouse	PMID:15322135
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q6P926	Mouse	PMID:18418073
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q64127	Mouse	PMID:10562550
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q61687	Mouse	PMID:8978696
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q62318	Mouse	PMID:8978696
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q62318	Mouse	PMID:10562550
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	PR:Q9Z103	Mouse	PMID:17222401
Molecular Function	GO:0005515	protein binding	Cbx5	IPI	MGI:MGI:105369	Mouse	PMID:8978696
Molecular Function	GO:0044877	protein-containing complex binding	CBX5	IDA		Human	PMID:19617346
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	Cbx5	IPI	UniProtKB:Q99N13	Mouse	MGI:MGI:4359370|PMID:12242305
Molecular Function	GO:0043021	ribonucleoprotein complex binding	CBX5	IDA		Human	PMID:19617346
Cellular Component	GO:0010369	chromocenter	Cbx5	IDA		Mouse	PMID:22101327
Cellular Component	GO:0010369	chromocenter	Cbx5	IDA		Mouse	PMID:17284516
Cellular Component	GO:0010369	chromocenter	Cbx5	IDA		Mouse	PMID:20219459
Cellular Component	GO:0000781	chromosome, telomeric region	CBX5	HDA		Human	PMID:19135898
Cellular Component	GO:0000781	chromosome, telomeric region	Cbx5	IDA		Mouse	MGI:MGI:4454526|PMID:20110566
Cellular Component	GO:0000792	heterochromatin	Cbx5	IDA		Mouse	PMID:10318760
Cellular Component	GO:0000792	heterochromatin	Cbx5	IDA		Mouse	PMID:14730304
Cellular Component	GO:0000792	heterochromatin	Cbx5	IDA		Mouse	PMID:15070898
Cellular Component	GO:0000792	heterochromatin	Cbx5	IDA		Mouse	PMID:15998811
Cellular Component	GO:0000118	histone deacetylase complex	Cbx5	IDA		Mouse	MGI:MGI:4359370|PMID:12242305
Cellular Component	GO:0035097	histone methyltransferase complex	Cbx5	IDA		Mouse	MGI:MGI:4359370|PMID:12242305
Cellular Component	GO:0000776	kinetochore	Cbx5	IDA		Mouse	PMID:14519686
Cellular Component	GO:0005730	nucleolus	CBX5	IDA		Human	PMID:9636146
Cellular Component	GO:0005730	nucleolus	Cbx5	IDA		Mouse	PMID:10318760
Cellular Component	GO:0005654	nucleoplasm	CBX5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CBX5	IDA		Human	PMID:19617346
Cellular Component	GO:0005634	nucleus	CBX5	IDA		Human	PMID:19783980
Cellular Component	GO:0005634	nucleus	CBX5	IDA		Human	PMID:28977666
Cellular Component	GO:0005634	nucleus	CBX5	IDA		Human	PMID:9636146
Cellular Component	GO:0005634	nucleus	Cbx5	IDA		Mouse	PMID:17284516
Cellular Component	GO:0005634	nucleus	Cbx5	IDA		Mouse	PMID:10318760
Cellular Component	GO:0005721	pericentric heterochromatin	Cbx5	IDA		Mouse	MGI:MGI:4454526|PMID:20110566
Cellular Component	GO:0016605	PML body	CBX5	IMP		Human	PMID:9636146
Cellular Component	GO:0032991	protein-containing complex	CBX5	IDA		Human	PMID:19617346
Cellular Component	GO:1990904	ribonucleoprotein complex	CBX5	IDA		Human	PMID:19617346
Cellular Component	GO:0090734	site of DNA damage	CBX5	IMP		Human	PMID:27248496
Cellular Component	GO:0017053	transcription repressor complex	Cbx5	IDA		Mouse	MGI:MGI:4359370|PMID:12242305
Biological Process	GO:0006974	DNA damage response	CBX5	IMP		Human	PMID:27248496
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CBX5	IMP		Human	PMID:9636146
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CBX5	IDA		Human	PMID:9636147
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CBX5	IMP		Human	PMID:9636147
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cbx5	IDA		Mouse	PMID:10562550
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CBX5	IMP		Human	PMID:19617346

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern