Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CBX8
  • Mouse genes Cbx8
  • Rat genes Cbx8
  • Zfish genes cbx8a,cbx8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cbx8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035064	methylated histone binding	CBX8	IDA		Human	PMID:21029866
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q92993	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O00257	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8IXK0	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q99496	Human	PMID:17332741
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q99496	Human	PMID:18927235
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35227	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8IXK0	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q99496	Human	PMID:19636380
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9HCE1	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35227	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P51784	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q93009	Human	PMID:20601937
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35227	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q06587	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q3KNV8	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q86SE9	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q99496	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BSM1	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BYE7	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9HCE1	Human	PMID:21282530
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q92993	Human	PMID:22094252
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P42568	Human	PMID:23260655
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O00257	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35227	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q06587	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8IXK0	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q99496	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:A1L4K1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O43829	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35711	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q06587	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q12800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q13422	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q2TAC2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q6NT76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q7L273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8IXK0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96D09	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96JN2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96KN7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BZW7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9UJV3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9UL42	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O00257	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P16401	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q06587	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q86SE9	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q99496	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q6W2J9	Human	PMID:27505670
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BSM1	Human	PMID:27505670
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35227	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q06587	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q3KNV8	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q6W2J9	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q86SE9	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8IXK0	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q99496	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BSM1	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BYE7	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35227	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BYE7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P16401	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:A0A0C4DFT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:A1L4K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O15160	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O15231	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O43829	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O75420	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:O94929-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P08670	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P23508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P51114-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q06587	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q12800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q13137	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q13422-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q13643	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q15742	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q495M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q4V328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q6NT76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q7L273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q86VP1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q86VW0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q86WH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8IYB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8ND90	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q8WWB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96BR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96C00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96D09	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96ED9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96N16	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96N21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q96RU7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BRK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BWT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9BYV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9C0D0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9NQX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9UBB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9UL42	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9Y333	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:Q9Y3Q8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CBX8	IPI	UniProtKB:P35226	Human	PMID:34316702
Molecular Function	GO:0005515	protein binding	Cbx8	IPI	UniProtKB:Q9CQJ4	Mouse	MGI:MGI:3715707|PMID:17296600
Molecular Function	GO:0005515	protein binding	Cbx8	IPI	PR:P25916	Mouse	PMID:16359901
Molecular Function	GO:0005515	protein binding	Cbx8	IPI	PR:Q9CQJ4	Mouse	PMID:16359901
Molecular Function	GO:0005515	protein binding	Cbx8	IPI	PR:O35730	Mouse	PMID:16359901
Molecular Function	GO:0003727	single-stranded RNA binding	Cbx8	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Molecular Function	GO:0097027	ubiquitin-protein transferase activator activity	Cbx8	IDA		Mouse	PMID:16359901
Cellular Component	GO:0000785	chromatin	CBX8	IDA		Human	PMID:19636380
Cellular Component	GO:0000792	heterochromatin	Cbx8	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Cellular Component	GO:0005654	nucleoplasm	CBX8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CBX8	IDA		Human	PMID:21282530
Cellular Component	GO:0005634	nucleus	Cbx8	IDA		Mouse	MGI:MGI:3619779|PMID:16537902
Cellular Component	GO:0005634	nucleus	Cbx8	IDA		Mouse	PMID:19796622
Cellular Component	GO:0031519	PcG protein complex	CBX8	IDA		Human	PMID:21282530
Cellular Component	GO:0035102	PRC1 complex	CBX8	IDA		Human	PMID:12167701
Cellular Component	GO:0035102	PRC1 complex	CBX8	IDA		Human	PMID:19636380
Cellular Component	GO:0035102	PRC1 complex	Cbx8	IDA		Mouse	PMID:16359901
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Cbx8	IEP		Rat	PMID:23572236|RGD:9586727
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	cbx8b	IMP		Zfish	PMID:24240475
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CBX8	IMP		Human	PMID:19636380
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CBX8	IMP		Human	PMID:21282530
Biological Process	GO:0008284	positive regulation of cell population proliferation	Cbx8	IMP		Rat	PMID:23572236|RGD:9586727
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	Cbx8	IMP		Rat	PMID:23572236|RGD:9586727
Biological Process	GO:0045739	positive regulation of DNA repair	Cbx8	IMP		Rat	PMID:23572236|RGD:9586727

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern