Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCAR2
  • Mouse genes Ccar2
  • Rat genes Ccar2
  • Zfish genes ccar2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccar2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	CCAR2	IPI	UniProtKB:Q96EB6	Human	PMID:18235501
Molecular Function	GO:0019899	enzyme binding	CCAR2	IPI	UniProtKB:O43463	Human	PMID:19218236
Molecular Function	GO:0019899	enzyme binding	CCAR2	IPI	UniProtKB:Q96EB6	Human	PMID:23382074
Molecular Function	GO:0004857	enzyme inhibitor activity	CCAR2	IDA		Human	PMID:18235501
Molecular Function	GO:0004857	enzyme inhibitor activity	CCAR2	IDA		Human	PMID:18235502
Molecular Function	GO:0004857	enzyme inhibitor activity	CCAR2	IMP	UniProtKB:O43463	Human	PMID:19218236
Molecular Function	GO:0004857	enzyme inhibitor activity	Ccar2	IDA		Mouse	MGI:MGI:3848112|PMID:19218236
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:P01106	Human	PMID:17314511
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q96EB6	Human	PMID:18235501
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q96EB6	Human	PMID:18235502
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q9H4Z2	Human	PMID:19131338
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:P03372	Human	PMID:20074560
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q92731	Human	PMID:20074560
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:P38398	Human	PMID:20160719
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:O15379	Human	PMID:21030595
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q13547	Human	PMID:21030595
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q14814	Human	PMID:21030595
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q96EB6	Human	PMID:21030595
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q5BKZ1	Human	PMID:22446626
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:P20393	Human	PMID:23398316
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:P23508	Human	PMID:24824780
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:P55055	Human	PMID:25661920
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:Q13133	Human	PMID:25661920
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCAR2	IPI	UniProtKB:P02766	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ccar2	IPI	UniProtKB:Q3UV55	Mouse	MGI:MGI:5495335|PMID:23398316
Molecular Function	GO:0003723	RNA binding	CCAR2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	CCAR2	HDA		Human	PMID:22681889
Molecular Function	GO:0000993	RNA polymerase II complex binding	CCAR2	IDA		Human	PMID:22446626
Cellular Component	GO:0000785	chromatin	CCAR2	IDA		Human	PMID:23352644
Cellular Component	GO:0005737	cytoplasm	CCAR2	IDA		Human	PMID:15824730
Cellular Component	GO:0005737	cytoplasm	CCAR2	IDA		Human	PMID:20160719
Cellular Component	GO:0005737	cytoplasm	CCAR2	IDA		Human	PMID:24824780
Cellular Component	GO:0044609	DBIRD complex	CCAR2	IDA		Human	PMID:22446626
Cellular Component	GO:0005759	mitochondrial matrix	CCAR2	IDA		Human	PMID:15824730
Cellular Component	GO:0005654	nucleoplasm	CCAR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CCAR2	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005634	nucleus	CCAR2	IDA		Human	PMID:15824730
Cellular Component	GO:0005634	nucleus	CCAR2	IDA		Human	PMID:18445686
Cellular Component	GO:0005634	nucleus	CCAR2	IDA		Human	PMID:20074560
Cellular Component	GO:0005634	nucleus	CCAR2	IDA		Human	PMID:20160719
Cellular Component	GO:0005634	nucleus	CCAR2	IDA		Human	PMID:24824780
Cellular Component	GO:0005634	nucleus	CCAR2	IDA		Human	PMID:25661920
Cellular Component	GO:0005819	spindle	CCAR2	IDA		Human	PMID:18445686
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	CCAR2	IDA		Human	PMID:15824730
Biological Process	GO:0043086	negative regulation of catalytic activity	CCAR2	IMP		Human	PMID:21030595
Biological Process	GO:0043086	negative regulation of catalytic activity	Ccar2	IMP		Mouse	MGI:MGI:5640947|PMID:21030595
Biological Process	GO:0030308	negative regulation of cell growth	CCAR2	IMP		Human	PMID:25661920
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CCAR2	IMP		Human	PMID:20074560
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CCAR2	IDA		Human	PMID:20160719
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CCAR2	IMP		Human	PMID:25661920
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	CCAR2	IMP		Human	PMID:23352644
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	CCAR2	IDA		Human	PMID:23398316
Biological Process	GO:0043065	positive regulation of apoptotic process	CCAR2	IMP		Human	PMID:18235501
Biological Process	GO:0043065	positive regulation of apoptotic process	CCAR2	IMP		Human	PMID:18235502
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	CCAR2	IMP		Human	PMID:24824780
Biological Process	GO:2000003	positive regulation of DNA damage checkpoint	CCAR2	IMP		Human	PMID:23352644
Biological Process	GO:0042752	regulation of circadian rhythm	Ccar2	IMP		Mouse	MGI:MGI:5495335|PMID:23398316
Biological Process	GO:0032784	regulation of DNA-templated transcription elongation	CCAR2	IMP		Human	PMID:22446626
Biological Process	GO:0090311	regulation of protein deacetylation	CCAR2	IDA		Human	PMID:21030595
Biological Process	GO:0031647	regulation of protein stability	CCAR2	IDA		Human	PMID:23398316
Biological Process	GO:0009411	response to UV	CCAR2	IMP		Human	PMID:23352644
Biological Process	GO:0008380	RNA splicing	CCAR2	IMP		Human	PMID:22446626

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern