Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCDC22
  • Mouse genes Ccdc22
  • Rat genes Ccdc22
  • Zfish genes ccdc22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccdc22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097602	cullin family protein binding	CCDC22	IDA		Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q13616	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q13618	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q7Z4G1	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q86VX2	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q86X83	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q8N668	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9GZQ3	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9H0A8	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9NX08	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9P000	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9UBI1	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9Y6G5	Human	PMID:23563313
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:A8K0Z3	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q567U6	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q641Q2	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q7Z3J2	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q8N668	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9Y4E1	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:P63261	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q567U6	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q7Z4G1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q86X83	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q8N668	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9GZQ3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9H0A8	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9NX08	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9P000	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9UBI1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9Y6G5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q567U6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q86X83	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q8N668	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9GZQ3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9H0A8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9NX08	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9P000	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9UBI1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9Y6G5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q15036	Human	PMID:28892079
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q7Z3J2|UniProtKB:Q86X83|UniProtKB:Q8N668|UniProtKB:Q9NX08|UniProtKB:Q9P000	Human	PMID:28892079
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q8N9S9	Human	PMID:28892079
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q567U6	Human	PMID:29778605
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q8N668	Human	PMID:29778605
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q9UBI1	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:P15289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:P0DTD1:PRO_0000449633	Human	PMID:32838362
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:P0DTD1:PRO_0000449633	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	CCDC22	IPI	UniProtKB:P0DTD1:PRO_0000449633	Human	PMID:34232536
Molecular Function	GO:0005515	protein binding	Ccdc22	IPI	UniProtKB:Q96A23	Mouse	MGI:MGI:5294308|PMID:12522145
Molecular Function	GO:0005515	protein binding	Ccdc22	IPI	UniProtKB:Q8BLR2|UniProtKB:Q8C166	Mouse	MGI:MGI:5294308|PMID:12522145
Cellular Component	GO:0005813	centrosome	CCDC22	IDA		Human	PMID:26638075
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB	CCDC22	IMP		Human	PMID:23563313
Biological Process	GO:0032456	endocytic recycling	CCDC22	IMP		Human	PMID:28892079
Biological Process	GO:0006893	Golgi to plasma membrane transport	CCDC22	IMP		Human	PMID:25355947
Biological Process	GO:0006878	intracellular copper ion homeostasis	CCDC22	IMP		Human	PMID:25355947
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	CCDC22	IMP		Human	PMID:23563313
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	CCDC22	IMP		Human	PMID:23563313
Biological Process	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	CCDC22	IMP		Human	PMID:23563313

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern