Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCDC3
  • Mouse genes Ccdc3
  • Rat genes Ccdc3
  • Zfish genes ccdc3a,ccdc3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccdc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005783	endoplasmic reticulum	CCDC3	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005576	extracellular region	CCDC3	IDA		Human	PMID:28827783
Cellular Component	GO:0005576	extracellular region	Ccdc3	IDA		Mouse	PMID:25605713
Biological Process	GO:0008610	lipid biosynthetic process	Ccdc3	IDA		Mouse	PMID:25605713
Biological Process	GO:0010629	negative regulation of gene expression	CCDC3	IDA		Human	PMID:28827783
Biological Process	GO:0010629	negative regulation of gene expression	Ccdc3	IMP		Mouse	PMID:28827783
Biological Process	GO:0051055	negative regulation of lipid biosynthetic process	Ccdc3	IMP		Mouse	PMID:28827783
Biological Process	GO:0045833	negative regulation of lipid metabolic process	CCDC3	IDA		Human	PMID:28827783
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	CCDC3	IMP		Human	PMID:25193116
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Ccdc3	IDA		Mouse	PMID:25605713
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	Ccdc3	IDA		Mouse	PMID:25605713

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern