Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCL11
  • Mouse genes Ccl11
  • Rat genes Ccl11
  • Zfish genes ccl35.1,ccl38.1,ccl38.6,ccl38a.3,ccl38a.4,ccl38a.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccl11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031728	CCR3 chemokine receptor binding	CCL11	IDA		Human	PMID:11425309
Molecular Function	GO:0008009	chemokine activity	CCL11	IDA		Human	PMID:10072545
Molecular Function	GO:0008009	chemokine activity	Ccl11	IDA		Rat	PMID:9458816|RGD:69985
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:P27487	Human	PMID:18275857
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:P27487	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:P51677	Human	PMID:23597562
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:P02776	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:P02778	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:P13501	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:P48061	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:Q9NRJ3	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL11	IPI	UniProtKB:Q9Y4X3	Human	PMID:28381538
Molecular Function	GO:0046983	protein dimerization activity	CCL11	IDA		Human	PMID:9712872
Molecular Function	GO:0048018	receptor ligand activity	CCL11	IDA		Human	PMID:11425309
Cellular Component	GO:0005576	extracellular region	CCL11	IDA		Human	PMID:20041150
Cellular Component	GO:0005615	extracellular space	Ccl11	IDA		Rat	PMID:9458816|RGD:69985
Biological Process	GO:0007015	actin filament organization	Ccl11	IDA		Rat	PMID:12413953|RGD:4145648
Biological Process	GO:0060444	branching involved in mammary gland duct morphogenesis	Ccl11	IMP	MGI:MGI:2384435	Mouse	PMID:10804170
Biological Process	GO:0002544	chronic inflammatory response	Ccl11	IEP		Rat	PMID:10861753|RGD:4145481
Biological Process	GO:0007010	cytoskeleton organization	CCL11	IDA		Human	PMID:10072545
Biological Process	GO:0048245	eosinophil chemotaxis	CCL11	IDA		Human	PMID:10072545
Biological Process	GO:0048245	eosinophil chemotaxis	Ccl11	IDA		Rat	PMID:9458816|RGD:69985
Biological Process	GO:0048245	eosinophil chemotaxis	Ccl11	IMP		Rat	PMID:9531320|RGD:4145483
Biological Process	GO:0070371	ERK1 and ERK2 cascade	Ccl11	IGI	RGD:619755	Rat	PMID:12413953|RGD:4145648
Biological Process	GO:0007611	learning or memory	Ccl11	IDA		Mouse	MGI:MGI:6211487|PMID:21886162
Biological Process	GO:0060763	mammary duct terminal end bud growth	Ccl11	IMP	MGI:MGI:2384435	Mouse	PMID:10804170
Biological Process	GO:0002551	mast cell chemotaxis	Ccl11	IDA		Rat	PMID:12413953|RGD:4145648
Biological Process	GO:0050768	negative regulation of neurogenesis	Ccl11	IDA		Mouse	MGI:MGI:6211487|PMID:21886162
Biological Process	GO:0030838	positive regulation of actin filament polymerization	CCL11	IDA		Human	PMID:19525930
Biological Process	GO:0045766	positive regulation of angiogenesis	Ccl11	IMP		Mouse	MGI:MGI:3850576|PMID:19525930
Biological Process	GO:0030335	positive regulation of cell migration	CCL11	IDA		Human	PMID:19525930
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	CCL11	IDA		Human	PMID:19525930
Biological Process	GO:0043547	positive regulation of GTPase activity	CCL11	IDA		Human	PMID:19525930
Biological Process	GO:0008360	regulation of cell shape	CCL11	IDA		Human	PMID:10072545
Biological Process	GO:0035962	response to interleukin-13	Ccl11	IEP		Rat	PMID:15953562|RGD:8693662
Biological Process	GO:0070670	response to interleukin-4	Ccl11	IEP		Rat	PMID:11071660|RGD:4145480

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern