Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCL19
  • Mouse genes Ccl19
  • Rat genes Ccl19
  • Zfish genes ccl19a.1,ccl19a.2,ccl19b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccl19

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048020	CCR chemokine receptor binding	CCL19	IPI	UniProtKB:O00421	Human	PMID:20002784
Molecular Function	GO:0031735	CCR10 chemokine receptor binding	CCL19	IDA		Human	PMID:10706668
Molecular Function	GO:0031732	CCR7 chemokine receptor binding	Ccl19	IPI	UniProtKB:P32248	Mouse	MGI:MGI:5788401|PMID:9507024
Molecular Function	GO:0008009	chemokine activity	CCL19	IDA		Human	PMID:15778365
Molecular Function	GO:0008009	chemokine activity	Ccl19	IDA		Mouse	MGI:MGI:5284817|PMID:12200351
Molecular Function	GO:0042379	chemokine receptor binding	CCL19	IDA		Human	PMID:23341447
Molecular Function	GO:0005515	protein binding	CCL19	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Cellular Component	GO:0009897	external side of plasma membrane	Ccl19	IDA		Mouse	PMID:19008373
Biological Process	GO:0048469	cell maturation	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0098586	cellular response to virus	CCL19	IMP		Human	PMID:25754930
Biological Process	GO:0002407	dendritic cell chemotaxis	CCL19	IDA		Human	PMID:15778365
Biological Process	GO:0002407	dendritic cell chemotaxis	Ccl19	IDA		Mouse	MGI:MGI:5284790|PMID:16027136
Biological Process	GO:0002407	dendritic cell chemotaxis	Ccl19	IDA		Mouse	MGI:MGI:5284817|PMID:12200351
Biological Process	GO:0009953	dorsal/ventral pattern formation	ccl19a.1	IGI	ZFIN:ZDB-MRPHLNO-121213-1,ZFIN:ZDB-MRPHLNO-121213-2	Zfish	PMID:23055828
Biological Process	GO:0009953	dorsal/ventral pattern formation	ccl19a.1	IMP	ZFIN:ZDB-MRPHLNO-121213-2	Zfish	PMID:23055828
Biological Process	GO:0001768	establishment of T cell polarity	CCL19	IDA		Human	PMID:12729902
Biological Process	GO:0001771	immunological synapse formation	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0097029	mature conventional dendritic cell differentiation	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0002408	myeloid dendritic cell chemotaxis	CCL19	IDA		Human	PMID:14592837
Biological Process	GO:2000669	negative regulation of dendritic cell apoptotic process	CCL19	IDA		Human	PMID:15059845
Biological Process	GO:2000147	positive regulation of cell motility	CCL19	IDA		Human	PMID:15778365
Biological Process	GO:0050921	positive regulation of chemotaxis	Ccl19	IDA		Mouse	MGI:MGI:5788401|PMID:9507024
Biological Process	GO:0002606	positive regulation of dendritic cell antigen processing and presentation	Ccl19	IMP		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:2000549	positive regulation of dendritic cell dendrite assembly	Ccl19	IDA		Mouse	MGI:MGI:5284817|PMID:12200351
Biological Process	GO:0045807	positive regulation of endocytosis	Ccl19	IDA		Mouse	MGI:MGI:5284790|PMID:16027136
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	CCL19	IDA		Human	PMID:15778365
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	CCL19	IMP	UniProtKB:O00182	Human	PMID:25754930
Biological Process	GO:0010560	positive regulation of glycoprotein biosynthetic process	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0043547	positive regulation of GTPase activity	Ccl19	IDA		Mouse	MGI:MGI:2667257|PMID:12609829
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	CCL19	IDA		Human	PMID:15059845
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0032735	positive regulation of interleukin-12 production	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0046330	positive regulation of JNK cascade	CCL19	IDA		Human	PMID:15778365
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Ccl19	IDA		Mouse	MGI:MGI:5284790|PMID:16027136
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	CCL19	IDA		Human	PMID:21051556
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	CCL19	IDA		Human	PMID:15059845
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	CCL19	IDA		Human	PMID:15059845
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	CCL19	IDA		Human	PMID:15778365
Biological Process	GO:0045860	positive regulation of protein kinase activity	CCL19	IDA		Human	PMID:14592837
Biological Process	GO:0045860	positive regulation of protein kinase activity	CCL19	IDA		Human	PMID:15059845
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	CCL19	IDA		Human	PMID:15059845
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	CCL19	IDA		Human	PMID:15778365
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	Ccl19	IDA		Mouse	MGI:MGI:2667257|PMID:12609829
Biological Process	GO:0042102	positive regulation of T cell proliferation	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0045627	positive regulation of T-helper 1 cell differentiation	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453
Biological Process	GO:0060491	regulation of cell projection assembly	Ccl19	IDA		Mouse	MGI:MGI:5284817|PMID:12200351
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	CCL19	IDA		Human	PMID:14592837
Biological Process	GO:0071731	response to nitric oxide	CCL19	IDA		Human	PMID:16249377
Biological Process	GO:0034695	response to prostaglandin E	CCL19	IDA		Human	PMID:14592837
Biological Process	GO:0031295	T cell costimulation	Ccl19	IDA		Mouse	MGI:MGI:3576832|PMID:15845453

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern