Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCL20
  • Mouse genes Ccl20
  • Rat genes Ccl20
  • Zfish genes ccl20a.3,ccl20b,ccl20l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccl20

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031731	CCR6 chemokine receptor binding	CCL20	IDA		Human	PMID:12081481
Molecular Function	GO:0031731	CCR6 chemokine receptor binding	CCL20	IDA		Human	PMID:20068036
Molecular Function	GO:0031731	CCR6 chemokine receptor binding	Ccl20	IDA		Mouse	MGI:MGI:5784982|PMID:20068036
Molecular Function	GO:0008009	chemokine activity	Ccl20	IDA		Rat	PMID:9916893|RGD:69987
Molecular Function	GO:0005125	cytokine activity	Ccl20	IDA		Mouse	PMID:9862452
Molecular Function	GO:0005515	protein binding	CCL20	IPI	UniProtKB:Q15311	Human	PMID:17703191
Molecular Function	GO:0005515	protein binding	CCL20	IPI	UniProtKB:Q15311	Human	PMID:18239685
Molecular Function	GO:0005515	protein binding	CCL20	IPI	UniProtKB:P02776	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL20	IPI	UniProtKB:P13501	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL20	IPI	UniProtKB:P48061	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	Ccl20	IPI	PR:O54689	Mouse	PMID:9862452
Cellular Component	GO:0005615	extracellular space	Ccl20	IDA		Rat	PMID:19428685|RGD:7488896
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	CCL20	IDA		Human	PMID:25122636
Biological Process	GO:0060326	cell chemotaxis	CCL20	IDA		Human	PMID:23765988
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Ccl20	IEP		Rat	PMID:15618187|RGD:7483631
Biological Process	GO:0071223	cellular response to lipoteichoic acid	Ccl20	IEP		Rat	PMID:15618187|RGD:7483631
Biological Process	GO:0071310	cellular response to organic substance	Ccl20	IEP		Rat	PMID:15618187|RGD:7483631
Biological Process	GO:0006935	chemotaxis	CCL20	IDA		Human	PMID:20068036
Biological Process	GO:0006935	chemotaxis	Ccl20	IDA		Mouse	MGI:MGI:5784982|PMID:20068036
Biological Process	GO:0006935	chemotaxis	Ccl20	IDA		Rat	PMID:9916893|RGD:69987
Biological Process	GO:0042742	defense response to bacterium	ccl20a.3	IDA		Zfish	PMID:29572872
Biological Process	GO:0006955	immune response	ccl20a.3	IDA		Zfish	PMID:29572872
Biological Process	GO:0032730	positive regulation of interleukin-1 alpha production	Ccl20	IDA		Rat	PMID:19428685|RGD:7488896
Biological Process	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	Ccl20	IDA		Rat	PMID:19428685|RGD:7488896
Biological Process	GO:2000406	positive regulation of T cell migration	CCL20	IDA		Human	PMID:23620790
Biological Process	GO:0072678	T cell migration	Ccl20	IDA		Mouse	MGI:MGI:5784970|PMID:24638065
Biological Process	GO:0072678	T cell migration	Ccl20	IDA		Mouse	MGI:MGI:3820359|PMID:19050256
Biological Process	GO:0072679	thymocyte migration	Ccl20	IDA		Mouse	MGI:MGI:5784970|PMID:24638065
Biological Process	GO:0042060	wound healing	Ccl20	IEP		Rat	PMID:21881592|RGD:7483606

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern