Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCL25
  • Mouse genes Ccl25
  • Rat genes Ccl25
  • Zfish genes ccl25a,ccl25b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccl25

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031735	CCR10 chemokine receptor binding	CCL25	IDA		Human	PMID:10706668
Molecular Function	GO:0008009	chemokine activity	CCL25	IDA		Human	PMID:18308860
Molecular Function	GO:0008009	chemokine activity	Ccl25	IDA		Mouse	PMID:10623805
Molecular Function	GO:0008009	chemokine activity	ccl25b	IDA		Zfish	PMID:18482437
Molecular Function	GO:0042379	chemokine receptor binding	CCL25	IDA		Human	PMID:23341447
Molecular Function	GO:0005515	protein binding	CCL25	IPI	UniProtKB:P02776	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL25	IPI	UniProtKB:P10720	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL25	IPI	UniProtKB:P13501	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL25	IPI	UniProtKB:P48061	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCL25	IPI	UniProtKB:Q92583	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	Ccl25	IPI	PR:Q9WUT7	Mouse	PMID:10623805
Biological Process	GO:0060326	cell chemotaxis	CCL25	IDA		Human	PMID:18308860
Biological Process	GO:0060326	cell chemotaxis	Ccl25	IDA		Mouse	MGI:MGI:1351362|PMID:10623805
Biological Process	GO:0006935	chemotaxis	Ccl25	IDA		Mouse	PMID:10623805
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CCL25	IDA		Human	PMID:18308860
Biological Process	GO:0050900	leukocyte migration	Ccl25	IDA		Mouse	PMID:15358618
Biological Process	GO:0097534	lymphoid lineage cell migration	Ccl25	IDA		Mouse	PMID:15358618
Biological Process	GO:0097535	lymphoid lineage cell migration into thymus	ccl25a	IGI	ZFIN:ZDB-MRPHLNO-071113-1,ZFIN:ZDB-MRPHLNO-121001-4	Zfish	PMID:22342843
Biological Process	GO:0097535	lymphoid lineage cell migration into thymus	ccl25a	IMP	ZFIN:ZDB-MRPHLNO-121001-4	Zfish	PMID:22342843
Biological Process	GO:0097535	lymphoid lineage cell migration into thymus	ccl25b	IGI	ZFIN:ZDB-MRPHLNO-071113-1,ZFIN:ZDB-MRPHLNO-121001-6	Zfish	PMID:22342843
Biological Process	GO:1903237	negative regulation of leukocyte tethering or rolling	CCL25	IDA		Human	PMID:18308860
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	CCL25	IDA		Human	PMID:18308860
Biological Process	GO:2000471	regulation of hematopoietic stem cell migration	ccl25b	IMP	ZFIN:ZDB-MRPHLNO-171018-1	Zfish	PMID:28803829
Biological Process	GO:1902033	regulation of hematopoietic stem cell proliferation	ccl25b	IMP	ZFIN:ZDB-MRPHLNO-171018-1	Zfish	PMID:28803829
Biological Process	GO:0007165	signal transduction	Ccl25	IDA		Mouse	MGI:MGI:1351362|PMID:10623805
Biological Process	GO:0072679	thymocyte migration	ccl25a	IMP	ZFIN:ZDB-MRPHLNO-121010-3	Zfish	PMID:22842207
Biological Process	GO:0072679	thymocyte migration	ccl25a	IMP	ZFIN:ZDB-MRPHLNO-121010-4	Zfish	PMID:22842207
Biological Process	GO:0048538	thymus development	ccl25a	IMP		Zfish	PMID:19559469

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern